Synthesis and biological characterization of human monocyte chemoattractant protein 1 (MCP-1) and its analogs

Journal of Peptide Science

Volumn 12, Issue 1, 2006, Pages 25-32

  Kruszynski, Marian ^a   Stowell, Nicole ^a   Das, Anuk ^a   Seideman, Jonathan ^a   Tsui, Ping ^a   Brigham Burke, Michael ^a   Nemeth, Jennifer F ^a   Sweet, Raymond ^a   Heavner, George A ^a  

^a CENTOCOR INC   (United States)

Author keywords

Analogs; BIAcore; Calcium mobilization; Chemotaxis; MCP 1; Monoclonal antibodies (mAbs); Peptide synthesis; Solid phase synthesis

Indexed keywords

CHEMOKINE RECEPTOR CCR2; MONOCLONAL ANTIBODY; MONOCYTE CHEMOTACTIC PROTEIN; MONOCYTE CHEMOTACTIC PROTEIN 1;

AFFINITY CHROMATOGRAPHY; AMINO ACID SEQUENCE; ANTIBODY PRODUCTION; ANTIGEN BINDING; ARTICLE; BINDING AFFINITY; BINDING COMPETITION; CALCIUM MOBILIZATION; CAPILLARY ELECTROPHORESIS; CELL CULTURE; CHEMOTAXIS; DISULFIDE BOND; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; LIGAND BINDING; MASS SPECTROMETRY; MOLECULAR WEIGHT; OXIDATION; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN DETERMINATION; PROTEIN PURIFICATION; SEQUENCE ANALYSIS; SOLID PHASE SYNTHESIS; SURFACE PLASMON RESONANCE;

AMINO ACID SEQUENCE; ANTIBODIES, MONOCLONAL; BINDING, COMPETITIVE; CALCIUM; CELL LINE; CHEMOKINE CCL2; CHEMOTAXIS; HUMANS; LIGANDS; MOLECULAR SEQUENCE DATA; MOLECULAR WEIGHT; PROTEIN BINDING; RECEPTORS, CHEMOKINE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 29844447643     PISSN: 10752617     EISSN: None     Source Type: Journal    
DOI: 10.1002/psc.680     Document Type: Article

References (23)

1. Furutani Y, Nomura H, Notake M, Oyamada Y, Fukui T, Yamada Mi, Larsen CG, Oppenheim JJ, Matsushima K. Cloning and sequencing of the CDNA for human monocyte chemotactic and activating factor (MCAF). Biochem. Biophys. Res. Commun. 1989; 159: 249-255.
2. Robinson EA, Yoshimura T, Leonard EJ, Tanaka S, Griffin PaR, Shabanowitz: J, Hunt DF, Appella E. Complete amino acid sequence of a human monocyte chemoattractant, a putative mediator of cellular immune reactions. Proc. Natl Acad. Sci. USA 1989; 86: 1850-1854.
3. Lubkowski J, Bujacz G, Boque L, Domaille PJ, Handel TM, Wlodawer A. The structure of MCP-1 in two crystal forms provides a rare example of variable quaternary interactions. Nat. Struct. Biol. 1997; 4: 64-69.
4. Clark-Lewis I, Hood LE, Kent SBH. Role of disulfide bridges in determining the biological activity of interleukin 3. Proc. Natl Acad. Sci. USA 1988; 85: 7897-7901.
5. Clark-Lewis I, Aebersold R, Ziltener H, Schrader JW, Hood LE, Kent SBH. Automated chemical synthesis of a protein growth factor for hemopoietic cells, interleukin-3. Science 1986; 231: 134-139.
6. Clark-Lewis I, Moser B, Walz A, Baggiolini M, Scott GJ, Aebersold R. Chemical synthesis, purification, and characterization of two inflammatory proteins, neutrophil activating peptide 1 (interleukinin-8) and neutrophil activating peptide 2. Biochemistry 1991; 30: 3128-3135.
7. Clark-Dewis I, Schumacher C, Baggiolini M, Moser B. Structure-activity relationships of interleukin-8 determined using chemically synthesized analogs. J. Biol. Chem. 1991; 266: 23128-23134.
8. Clark-Lewis I, Dewald B, Geiser T, Moser B, Baggiolini M. Platelet factor 4 binds to interleukin 8 receptors and activates neutrophils when its N terminus is modified with Glu-Leu-Arg. Proc. Natl Acad. Sci. USA 1993; 90: 3574-3577.
9. Geiser T, Dewald B, Ehrengruber MU, Clark-Dewis I, Baggiolini M. The interleukin-8-related chemotactic cytokines GROα, GROβ, and GROγ activate human neutrophil and basophil leukocytes. J. Biol. Chem. 1993; 268: 15419-15424.
10. Moser B, Dewald B, Barella L, Schumacher C, Baggiolini M, Clark-Dawis I. Interleukin-8 antagonists generated by N-terminal modification. J. Biol. Chem. 1993; 268: 7125-7128.
11. Clark-Lewis I, Dewald B, Loetscher M, Moser B, Baggiolini M. Structural requirements for interleukinin-8 function identified by design of analogs and CXC chemokine hybrids. J. Biol. Chem. 1994; 269: 16075-16081.
12. Gong J-H, Uguccioni M, Dewald B. Baggiolini M, Clark-Lewis I, RANTES and MCP-3 antagonists bind multiple chemokine receptors. J. Biol. Chem. 1996; 271: 10521-10527.
13. White P, Keyte JW, Bailey K, Bloomberg G. Expediting the Fmoc solid phase synthesis of long peptides through the application of dimethyloxazolidine dipeptides. J. Peptide Sci. 2004; 10: 18-26.
14. Escher SE, Kluver E, Adermann K. Fmoc-based synthesis of the human CC chemokine CCL14/HCC-1 by SPPS and native chemical ligation. Lett. Pcptide Sci. 2002; 8: 349-357.
15. Robertson N, Ramage R. Total chemical synthesis of deglycosylated human erythropoietin. J. Chem. Soc., Perkin Trans. 1 1999; 1015-1021.
16. Brown AR., Covington M, Newton RC, Ramage R, Welch P. The total chemical synthesis of monocyte chemotactic protein-1 (MCP-1). J. Peptide Sci. 1996; 2: 40-46.
17. Proost P, Van Leuven P, Wuyts A, Ebberink R, Opdenakker G, Van Damme J. Chemical synthesis, purification and folding of the human monocyte chemotactic proteins MCP-2 and MCP-3 into biologically active chemokines. Cytokine 1995; 7: 97-104.
18. Van Damme J, Proost P, Put W, Arens S, Lenaerts J-P, Conings R, Opdenakker G, Heremans H, Billiau A. Induction of monocyte chemotactic proteins MCP-1 and MCP-2 in human fibroblasts and leukocytes by cytokines and cytokine inducers. Chemical synthesis of MCP-2 and development ofa specific RIA. J. Immunol. 1994; 152: 5495-5502.
19. Tsuchiya S, Yamabe M, Yamaguchi Y, Kobayashi Y, Konno T, Tada K. Establishment and characterization of human acute monocytic leukemia cell line (THP-1). Int. J. Cancer 1980; 26: 171-176.
20. Funakoshi S, Fukuda H, Fujii N. Affinity purification method using a reversible biotinylating reagent for peptides synthesized by the solid-phase technique. J. Chromatogr. 1993; 638: 21-27.
21. Merrifield RB. Solid phase peptide synthesis. I. The synthesis of a tetrapeptide. J. Am. Chem. Soc. 1963; 85: 2140-2154.
22. Ball HL, Mascagni P. N-(2-chlorobenzyloxycarbonyloxy)-succinimide as a terminating agent for solid-phase peptide synthesis: application to a one-step purification procedure. Lett. Peptide Sci. 1995; 2: 49-57.
23. Jaenicke R, Rudolph R. In Protein Structure - A Practical Approach, Creighton TE (ed.). IRL Press: Oxford, 1990; 191-223.