Three new lignans, longipedunins A-C, from Kadsura longipedunculata and their inhibitory activity against HIV-1 protease

Chemical and Pharmaceutical Bulletin

Volumn 54, Issue 1, 2006, Pages 129-132

  Sun, Quan Zhong ^a   Chen, Dao Feng ^a   Ding, Pei Lan ^a   Ma, Chao Mei ^b   Kakuda, Hiroko ^c   Nakamura, Norio ^c   Hattori, Masao ^c  

^a FUDAN UNIVERSITY   (China)

^b PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^c UNIVERSITY OF TOYAMA   (Japan)

Author keywords

HIV 1 protease; Kadsura longipedunculata; Lignan; Longipedunin; X ray crystal structure

Indexed keywords

ACETYL BINANKADSURIN A; BENZOYL BINANKADSURIN A; LIGNAN DERIVATIVE; LONGIPEDUNIN A; LONGIPEDUNIN B; LONGIPEDUNIN C; PROTEINASE INHIBITOR; SCHISANLACTONE A; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; DRUG ACTIVITY; DRUG INHIBITION; DRUG ISOLATION; DRUG STRUCTURE; DRUG SYNTHESIS; IC 50; KADSURA LONGIPEDUNCULATA; MEDICINAL PLANT; NONHUMAN; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION; X RAY ANALYSIS;

CHROMATOGRAPHY, THIN LAYER; HIV PROTEASE INHIBITORS; HIV-1; HUMANS; KADSURA; LIGNANS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR CONFORMATION; SPECTROPHOTOMETRY, ULTRAVIOLET; X-RAY DIFFRACTION;

EID: 29844433855     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.54.129     Document Type: Article

References (12)

1. Ma C.-M., Nakamura N., Miyashiro H., Hattori M., Shimotohno K., Chem. Pharm. Bull., 47, 141-145 (1999).
2. Min B.-S., Nakamura N., Miyashiro H., Bae K.-W., Hattori M., Chem. Pharm. Bull., 46, 1607-1612 (1998).
3. Ma C.-M., Nakamura N., Hattori M., Kakuda H., Qiao J.-C., Yu H.-L., J. Nat. Prod., 63, 238-242 (2000).
4. Yang X.-W., Zhao J., Cui Y.-X., Liu X.-H., Ma C.-M., Hattori M., Zhang L.-H., J. Nat. Prod., 62, 1510-1513 (1999).
5. Ma C.-M., Nakamura N., Hattori M., Chem. Pharm. Bull., 49, 915-917 (2001).
6. Chen D.-F., Peng H.-Li., Jiang M.-H., Shi D.-W., Acta Academiae Medicinae Shanghai, 23 (Suppl.), 52-54 (1996).
7. Li L.-N., Xue H., Li X., Planta Med., 57, 169-171 (1991).
8. Ookawa N., Ikeya Y., Taguchi H., Yosioka I., Chem. Pharm. Bull., 29, 123-127 (1981).
9. Liu J.-S., Huang M.-F., Arnold G. F., Arnold E., Clardy J., Ayer W. A., Tetrahedron Lett., 24, 2351-2354 (1983).
10. Chen Y.-G., Wang P., Lin Z.-W., Sun H.-D., Qin K.-W., Xie Y., Phytochemistry, 48, 1059-1062 (1998).
11. Ikeya Y., Taguchi H., Yosioka I., Kobayashi H., Chem. Pharm. Bull., 27, 1383-1394 (1979).
12. Liu J.-S., Li L., Phytochemistry, 32, 1293-1296 (1993).