Quantification of faropenem in human plasma by high-performance liquid chromatography

Arzneimittel-Forschung/Drug Research

Volumn 55, Issue 12, 2005, Pages 762-766

  Nirogi, Ramakrishna V S ^a   Kandikere, Vishwottam N ^a   Shrivastava, Wishu ^a   Mudigonda, Koteshwara ^a  

^a SUVEN LIFE SCIENCES LTD   (India)

Author keywords

Antimicrobial drugs, lactam; CAS 106560 14 9; Faropenem, HPLC quantification in human plasma

Indexed keywords

ACETIC ACID; BETA LACTAM ANTIBIOTIC; BUFFER; FROPENEM; HYDROCHLOROTHIAZIDE; METHANOL; TRIETHYLAMINE;

ARTICLE; DEVICE; DRUG BLOOD LEVEL; DRUG DEGRADATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; METHODOLOGY; NORMAL HUMAN; PH; SOLID PHASE EXTRACTION; VALIDATION PROCESS;

EID: 29744462648     PISSN: 00044172     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0031-1296927     Document Type: Article

References (6)

1. Milazzo, I., Blandino, G., Caccamo, F. et al., Faropenem, a new oral penem: antibacterial activity against selected anaerobic and fastidious periodontal isolates. J. Antimicrob. Chemother. 51, 721 (2003)
2. Woodcock, J. M., Andrews, J. M., Brenwald, N. P. et al., The in vitro activity of faropenem, a novel oral penem. J. Antimicrob. Chemother. 39, 35 (1997)
3. Boswell, F. J., Andrews, J. M., Wise, R., Pharmacodynamic properties of faropenem demonstrated by studies of time-kill kinetic and post-antibiotic effect. J. Antimicrob. Chemother. 39, 415 (1997)
4. Goldstein E. J., Citron D. M., Merriam C. V. et al., Comparative in vitro activity of faropenem and 11 other antimicrobial agents against 405 aerobic and anaerobic pathogens isolated from skin and soft tissue infections from animal and human bites. J. Antimicrob. Chemother. 50, 411 (2002).
5. Hamilton-Miller, J. M., Chemical and microbiologic aspects of penems, a distinct class of β-lactams: Focus on faropenem. Pharmacotherapy 23, 1497 (2003)
6. Guidance for Industry: Bioanalytical Method Validation, US Department of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research, Rockville, MD, USA (2001)