Respiratory acidosis and acute respiratory distress syndrome: Time to trade in a bull market?

Critical Care Medicine

Volumn 34, Issue 1, 2006, Pages 229-231

  Broccard, Alain F ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Acute respiratory distress syndrome; Carbon dioxide; Hypercapnia; Lung injury; Mechanical ventilation; Respiratory acidosis

Indexed keywords

NITRIC OXIDE;

ADULT RESPIRATORY DISTRESS SYNDROME; ARTIFICIAL VENTILATION; CARBON DIOXIDE BREATHING; EDITORIAL; HUMAN; HYPERCAPNIA; LUNG INJURY; PRIORITY JOURNAL; RESPIRATORY ACIDOSIS; TIDAL VOLUME; VENTILATOR;

EID: 29744452641     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.CCM.0000190902.96831.93     Document Type: Editorial

References (25)

1. Dreyfuss D, Saumon G: Ventilator-induced lung injury: Lessons from experimental studies. Am J Respir Crit Care Med 1998; 157:294-323
2. Amato MB, Barbas CS, Medeiros DM, et al: Effect of a protective- ventilation strategy on mortality in the acute respiratory distress syndrome. N Engl J Med 1998; 338:347-354
3. Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. The Acute Respiratory Distress Syndrome Network. N Engl J Med 2000; 342:1301-1308
4. Corbridge TC, Wood LD, Crawford GP, et al: Adverse effects of large tidal volume and low PEEP in canine acid aspiration. Am Rev Respir Dis 1990; 142:311-315
5. Muscedere JG, Mullen JB, Gan K, et al: Tidal ventilation at low airway pressures can augment lung injury. Am J Respir Crit Care Med 1994; 149:1327-1334
6. Nuckton TJ, Alonso JA, Kallet RH, et al: Pulmonary dead-space fraction as a risk factor for death in the acute respiratory distress syndrome. N Engl J Med 2002; 346:1281-1286
7. Broccard AF, Hotchkiss JR, Vannay C, et al: Protective effects of hypercapnic acidosis on ventilator-induced lung injury. Am J Respir Crit Care Med 2001; 164:802-806
8. Sinclair SE, Kregenow DA, Lamm WJ, et al: Hypercapnic acidosis is protective in an in vivo model of ventilator-induced lung injury. Am J Respir Crit Care Med 2002; 166:403-408
9. Dreyfuss D, Soler P, Saumon G: Mechanical ventilation-induced pulmonary edema. Interaction with previous lung alterations. Am J Respir Crit Care Med 1995; 151:1568-1575
10. Kavanagh BP: Therapeutic hypercapnia: Careful science, better trials. Am J Respir Crit Care Med 2005; 171:96-97
11. Doerr CH, Gajic O, Berrios JC, et al: Hypercapnic acidosis impairs plasma membrane wound resealing in ventilator-injured lungs. Am J Respir Crit Care Med 2005; 171:1371-1377
12. Takeshita K, Suzuki Y, Nishio K, et al: Hypercapnic acidosis attenuates endotoxin-induced nuclear factor-[kappa]B activation. Am J Respir Cell Mol Biol 2003; 29:124-132
13. Laffey JG, Tanaka M, Engelberts D, et al: Therapeutic hypercapnia reduces pulmonary and systemic injury following In vivo lung reperfusion. Am J Respir Crit Care Med 2000; 162:2287-2294
14. Beachy JC, Weisman LE: Acute asphyxia affects neutrophil number and function in the rat. Crit Care Med 1993; 21:1929-1934
15. Rai S, Engelberts D, Laffey JG, et al: Therapeutic hypercapnia is not protective in the in vivo surfactant-depleted rabbit lung. Pediatr Res 2004; 55:42-49
16. Doerr CH, Gajic O, Berrios JC, et al: Hypercapnic acidosis impairs plasma membrane wound resealing in ventilator-injured lungs. Am J Respir Crit Care Med 2005; 171:1371-1377
17. Lang JD, Figueroa M, Sanders KD, et al: Hypercapnia via reduced rate and tidal volume contributes to lipopolysaccharide-induced lung injury. Am J Respir Crit Care Med 2005; 171:147-157
18. Kavanagh BP: Therapeutic hypercapnia: careful science, better trials. Am J Respir Crit Care Med 2005; 171:96-97
19. Broccard AF, Feihl F, Vannay C, et al: Effects of L-NAME and inhaled nitric oxide on ventilator-induced lung injury in isolated, perfused rabbit lungs. Crit Care Med 2004; 32:1872-1878
20. Lang JD, Figueroa M, Sanders KD, et al: Hypercapnia via reduced rate and tidal volume contributes to lipopolysaccharide-induced lung injury. Am J Respir Crit Care Med 2005; 171:147-157
21. Feihl F, Perret C: Permissive hypercapnia. How permissive should we be? Am J Respir Crit Care Med 1994; 150:1722-1737
22. Darioli R, Perret C: Mechanical controlled hypoventilation in status asthmaticus. Am Rev Respir Dis 1984; 129:385-387
23. Hickling KG, Walsh J, Henderson S, et al: Low mortality rate in adult respiratory distress syndrome using low-volume, pressure-limited ventilation with permissive hypercapnia: A prospective study. Crit Care Med 1994; 22:1568-1578
24. Kregenow DA, Rubenfeld GD, Hudson LD, et al: Hypercapnic acidosis and mortality in acute lung injury. Crit Care Med 2006; 34:1-7
25. Rai S, Engelberts D, Laffey JG, et al: Therapeutic hypercapnia is not protective in the in vivo surfactant-depleted rabbit lung. Pediatr Res 2004; 55:42-49