Activation of NF-κB and apoptosis of intestinal epithelial cells induced by hydrogen peroxide

Chinese Journal of Traumatology - English Edition

Volumn 5, Issue 4, 2002, Pages 209-213

  Li, Jianming ^a   Zhou, Hong ^a   Cai, Qian ^a   Xiao, Guangxia ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Intestinal epithelial cells; NF kappa B; Reactive oxygen species

Indexed keywords

HYDROGEN PEROXIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; POLYCLONAL ANTIBODY; REACTIVE OXYGEN METABOLITE;

APOPTOSIS; ARTICLE; FLOW CYTOMETRY; GEL MOBILITY SHIFT ASSAY; HUMAN; HUMAN CELL; IN VITRO STUDY; INTESTINE EPITHELIUM CELL; PATHOGENESIS; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ULTRASTRUCTURE; CELL CULTURE; CONFOCAL MICROSCOPY; INTESTINE MUCOSA; METABOLISM;

APOPTOSIS; HUMANS; HYDROGEN PEROXIDE; INTESTINAL MUCOSA; MICROSCOPY, CONFOCAL; NF-KAPPA B; REACTIVE OXYGEN SPECIES; TUMOR CELLS, CULTURED;

EID: 29744450912     PISSN: 10081275     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

1. MA L, LI A, Xiao GX. Experimental studies on gut origin infection. Acta Acad Medi Mili Tert 1990;12:1-68.
2. Liang GD. The latest experimental protocol of molecular biology. Beijing: Science Publishing House, 2001:1-5.
3. Li J. Study of intestinal barrier function disorders. Chin Med J 1999;79:581-582.
4. Zhao F, Shi TC, Shen TY, et al. Inhibitive effects of anti-oxidants on activation of NF-κB in bovine aorta endothelial cells. Acta Biochemica et Biophysica Sinica, 2000;32:342-346.
5. Zhong L, You JL, Xiao XZ et al. Role of NF-κB in protection of heat shock pretreatment against TNF-α induced endothelial cell apoptosis. Chin J Pathophysiol, 1999;15:436-440.
6. Jansen-Heininger YM, Poynter ME, Beauerle PA. Recent advances towards understanding redox mechanisms in the activation of nuclear factor kappaB. Free Radi Biol Med 2000;28:1317-1327.
7. Ding GJ, Fischer PA, Boltz RC, et al. Characterization and quantitation of NF-kappaB nuclear translocation induced by interleukin-1 and tumor necrosis factor-alpha. Development and use of a high capacity fluorescence cytometric system. J Biol Chem 1998;273:28897-28905.
8. Jones BE, Lo CR, Liu H, et al. Role of caspases and NF-kappaB signaling in hydrogen peroxide- and superoxide-induced hepatocyte apoptosis. Am J Physiol Gastrointest Live Physiol 2000;278:G693-699.
9. Kaltschmidt B, Kaltschmidt C, Hofmann TG, et al. The pro- or anti-apoptotic function of NF-kappaB is determined by the nature of the apoptotic stimulus. Eur J Biochem 2000;267:3828-2835.
10. 2+ reperfusion injury of cultured astrocytes: roles of reactive oxygen species and NF-kappaB activation. Eur J Neurosci 1999;11:4204-4212.
11. Dumont A, Hehner SP, Hofmann TG, et al. Hydrogen peroxide-induced apoptosis is CD95-independent, requires the release of mitochondria-derived reactive oxygen species and the activation of NF-kappaB. Oncogene 1999;18:747-757.
12. Frantz S, Kelly RA, Bourcier T. Role of TLR-2 in the activation of nuclear factor κB by oxidative stress in cardiac myocytes. J Biol Chem 2001;276:5197-5203.