Effects of ambient ELF magnetic fields: Variations in electrolyte levels in the brain and blood plasma

Gazi Medical Journal

Volumn 16, Issue 3, 2005, Pages 121-127

  Canseven, Ayşe G ^a   Seyhan, Nesrin ^a   Aydin, Ahmet ^b   Çevik, Cemal ^a   Işimer, Aşkin ^b  

^a GAZI UNIVERSITY   (Turkey)

^b GULHANE SCHOOL OF MEDICINE   (Turkey)

Author keywords

Brain Electrolytes; ELF Magnetic Fields; Guinea Pigs; Plasma Electrolytes

Indexed keywords

CALCIUM ION; COPPER ION; MAGNESIUM ION; POTASSIUM ION; SODIUM ION; ZINC ION;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ATOMIC ABSORPTION SPECTROMETRY; BLOOD ANALYSIS; BRAIN; BRAIN TISSUE; CELL MEMBRANE; CONTROLLED STUDY; ELECTROLYTE BLOOD LEVEL; FLAME PHOTOMETRY; GUINEA PIG; HEMOLYSIS; MAGNETIC FIELD; MALE; NONHUMAN; PLASMA;

EID: 29744450319     PISSN: 1300056X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (70)

1. Anderson LE, Kaune WT. Electric and Magnetic Fields at Extremely Low Frequency. In WHO Regional Publications: Nonionizing Radiation Protection: World Health Organization Regional Office for Europe. European Series, Second Ed., Copenhagen: 1989. No.25, p. 175-243.
2. Grandolfo M, Vecchia P. Natural and Man-Made Environmental Exposures to Static and ELF Electromagnetic Fields. In Grandolfo M, Michaelson SM, Rindi A. (eds): Biological Effects and Dosimetry of Static and ELF Electromagnetic Fields. New York: Plenum Press; 1985. p. 49-71.
3. WHO Fact Sheet 205. Electromagnetic Fields and Public Health: Extremely Low Frequency (ELF): 1998. (http://www.who.int/pehemf/publications/facts_press)
4. WHO Fact Sheet No 263. Electromagnetic Fields and Public Health-Extremely Low Frequency Fields and Cancer: 2001. (http://www. who.int/docstore/pehemf/ publications/facts_press/efact/efs263. htm)
5. Report of an Advisory Group on Non-Ionizing Radiation: ELF Electromagnetic Fields and the Risk of Cancer Doc. NRPB 2001, 12. No. 1, 3-179.
6. Matthes R, Vecchia P, McKinlay AF, Veyret B, Bernhardt JH. Exposure to Static and Low Frequency Electromagnetic Fields, Biological Effects and Health Consequences (0-100 kHz). International Commission on Non-Ionizing Radiation Protection (ICNIRP): 13/2003, Märkl-Druck, München, 2003.
7. IARC Non-Ionizing Radiation. Static and Extremely Low Frequency (ELF) Electric and Magnetic Fields. Part 1, Vol. 80, Lyon; 2002.
8. Häuf R. Hematological and Biochemical Effects of ELF Fields in Man - Laboratory Experiments. In Grandolfo M, Michaelson SM, Rindi A. (eds): Biological Effects and Dosimetry of Static and ELF Electromagnetic Fields. New York: Plenum Press; 1985. p. 525-538.
9. Phillips A. Power Politics: Playing with Children's Lives? Electronics World+Wireless World, Non-Ionizing Radiation 1992; February: 277-280.
10. Checcucci A. An Epidemiological Investigation of HV Substation Workers: Study Design and Preliminary Results. In Grandolfo M, Michaelson SM, Rindi A. (eds): Biological Effects and Dosimetry of Static and ELF Electromagnetic Fields. New York: Plenum Press; 1985. p. 557-570.
11. Cabanes J. Medical Control of Employees in the Electrical Industry Exposed to Low Frequency Electric Fields. In Grandolfo M, Michaelson SM, Rindi A. (eds): Biological Effects and Dosimetry of Static and ELF Electromagnetic Fields. New York: Plenum Press; 1985. p. 539-556.
12. Savitz DA, Howard W, Barnes FA, John EM, Tvrdik JG. Case-Control Study of Childhood Cancer and Exposure to 60 Hz Magnetic Fields. Am. J Epidem 1988; 128: 21-38.
13. Wertheimer N, Leeper E. Electrical Wiring Configurations and Childhood Cancer. Am J Epidem 1979; 109: 273-284.
14. Best S. Killing Fields: The Epidemiological Evidence, Electronics World + Wireless World. Non-Ionizing Radiation 1990; February: 98-106
15. Sheppard A, Eisenbud M. Biological Effects of Electric and Magnetic Fields of Extremely Low Frequency, New York University Press, 1977.
16. Frey AH. An Integration of the Data on Mechanisms with Particular Reference to Cancer. In Frey AH. (ed): Medical Intelligence Unit: On the Nature of Electromagnetic Field Interactions with Biological Systems. Austin USA: R.G. Landes Company; 1994. p.9.
17. Kheifets L. Childhood Leukemia and EMF. WHO-International Electromagnetic Field (EMF) Project, Workshop: Sensitivity of Children to EMF Exposure. Proceedings, 9-10 June 2004, Istanbul. Turkey.
18. Repacholi M. EMF: A Potential Environmental Risk for Children? WHO-International Electromagnetic Field (EMF) Project, Workshop: Sensitivity of Children to EMF Exposure. Proceedings, 9-10 June 2004, Istanbul, Turkey.
19. Markov M. Physics and Engineering Approaches Toward Environmental Importance of Electromagnetic Fields. World Congress on Medical Physics and Biomedical Engineering, Physics in Medicine & Biology 1994, 39a, 46, Rio de Janeiro, Brazil.
20. Milham SJ. Mortality from Leukemia in Workers Exposed to Electrical and Magnetic Fields, The New England J. Medicine 1982; 307: 949.
21. Tenford TS. Interaction of ELF Magnetic Fields with Living Matter. In Polk C, Postow E (eds): CRC Handbook of Biological Effects of Electromagnetic Fields. Boston: CRC Press; 1986. p. 197-228.
22. Dacha M, Accorsi A, Pierotti C, Vetrano F, Mantovani R. Guidi G, Conti R, Nicolini P. Studies on the Possible Biological Effects of 50 Hz Electric and/or Magnetic Fields: Evaluation of Some Glycolytic Enzymes, Glycolytic Flux, Energy, and Oxido-Reductive Potentials in Human Erytrocytes Exposed in Vitro to Power Frequency Fields. Bioelectromagnetics 1993; 14: 383-391.
23. Stuchly MA, Lecuyer DW, McLean J. Cancer Promotion in a Mouse-Skin Model by a 60 Hz Magnetic Field: I. Experimental Design and Exposure System. Bioelectromagnetics 1991; 12: 261-271.
24. Lyle DB, Wang X, Ayotte RD, Sheppard AR, Adey WR. Calcium Uptake by Leukemic and Normal T-Lymphocytes Exposed to Low Frequency Magnetic Fields. Bioelectromagnetics 1991; 12: 145-156.
25. Liburdy RP, Yost MG. Time Varying and Static Magnetic Fields Act in Combination to Alter Calcium Signal Transduction in the Lymphocyte. In Blank M. Ed.: Electricity and Magnetism in Biology and Medicine. USA: San Francisco Press, Inc; 1993. p. 331-334.
26. Adey WR. Biological Effects of Electromagnetic Fields. J Cellular Biochem 1992; 51: 410-416.
27. Blumenthal NC, Ricci J, Breger L, Zychlinsky A, Solomon H, Chen GG, Kuznetsov D, Dorfman R. Effects of Low Intensity AC and/ or DC Electromagnetic Fields on Cell Attachment and Induction of Apoptosis. Bioelectromagnetics, 1997; 18: 264-272.
28. Garcia-Sancho J, Montero M, Alvarez J, Fonteriz RI, Sanchez A. Effects of Extremely Low Frequency Electromagnetic Fields on Ion Transport in Several Mammalian Cells. Bioelectromagnetics, 1994; 15: 579-588.
29. Azanza MJ, Del Moral A. Cell Membrane Biochemistry and Neurobiological Approach to Biomagnetism. Progress in Neurobiology, 1994; 44: 518-601.
30. Canseven AG, Seyhan N, Mirshahidi S, Imir T. Immune Response of Guinea Pigs to AC Magnetic Fields. 2nd EMF Seminar in China: Electromagnetic Fields and Biological Effects, 2000, Xi'an, China, Proceedings pp: 229-235.
31. Walleczek J. Electromagnetic field effects on cell of the immune system: the role of calcium signalling. FASEB J. 1992; 6: 3177-3185.
32. Shau H, Kim AT, Hedríck CC, Lusis AJ, Tompkins C, Finney R, Leung DW, Paglia DE. Endogenous Natural Killer Enhancing Factor-B Increases Cellular Resistance to Oxidative Stresses. Free Radical Biology & Medicine, 1997; 22: 497-507.
33. de Seze R, Bouthet C, Tuffet S, Deschaux P, Caristan A, Moreau JM, Veyret B. Effects of Time-Varying Uniform Magnetic Fields on Natural Killer Cell Activity and Antibody Response in Mice. Bioelectromagnetics, 1993; 14: 405-412.
34. Canseven AG, Seyhan N, Cevik C. Does ELF Magnetic Field Alter Plasma Na+ and K+ Concentrations? The First International Biosciences Days, 1999 Antalya, Turkey, Abstract Book, P-104.
35. Canseven AG. Seyhan N. Changes in Skin Hydroxyproline Levels Under the Effect of Magnetic Fields. World Congress on Medical Physics and Biomedical Engineering, 2000 Navy Pier, Chicago (from CD/TU-B205-04).
36. Canseven AG, Özel Ü, Bilgihan A, Seyhan N. The Effect of ELF Magnetic Field Exposure on Kidney Myeloperoxidase (MPO) Activity. 13th Balkan Biochemical Biophysical Days & Meeting on Metabolic Disorders. 2003, Kuşadasi, Turkey, P96.
37. Canseven AG, Özel Ü, Bílgihan A, Seyhan N. Does ELF Magnetic Field Affect the Myeloperoxidase (MPO) Activity in the Lung. 11 th International Congress of the International Radiation Protection Association 2004 Madrid, Spain, ID 591.
38. Canseven AG, Seyhan N. Is There Any Relation Between Collagen Synthesis - 50 Hz Magnetic Fields - LIDC? International Electromagnetic Field (EMF) Project, Workshop: Sensitivity of Children to Electromagnetic Fields. 2004, Istanbul, Turkey, P6.
39. Seyhan N, Canseven AG, Güler G. Animal Studies on the Effects of ELF and Static EMF. Unesco-WHO International Seminar on Molecular and Cellular Mechanisms of Biological Effects of EMF. 2005, Yerevan Armenia (Noto Book in press)
40. Güler G, Atalay Seyhan N, Özoǧul C, Erdoǧan D. Biochemical and Structural Approach to Collagen Synthesis Under Electric Fields. Gen Physiol Biophys 1996; 15: 429-440.
41. Güler G, Atalay Seyhan N. Changes in Hydroxyproline Levels in Electric Field Tissue Interaction. Indian Journal of Biochemistry and Biophysics 1996; 33: 531-533.
42. Güler G, Atalay Seyhan N. The Interaction of Electric Field with Biological Systems I: Liver Hydroxyproline. Gazi Medical Journal 1995; 6: 125-129.
43. Atalay Seyhan N, Güler G, Koz M, Gönül B. Elektrik Alanin Böbreküstü Bezi MDA Seviyesine Etkisi. Türkiye Tip Dergisi 1994; 1: 161-167.
44. Güler G, Hardalaç F, Aricioǧlu A. Examination of Electric Field Effects on Lipid Peroxidation and Antioxidant Enzymes by Using Multilayer Perceptron Neural Network. G.U. Journal Science 2005; 18: 27-37.
45. Güler G, Seyhan N, Aricioǧlu A. Effects of Electric Fields on Radical and Antioxidant Enzymes Levels in Spleen and Testis of Guinea Pigs. Gazi Medical Journal 2004; 2: 99-104.
46. Keskil İS, Keskil ZA, Canseven AG, Seyhan N. No effect of 50 Hz Magnetic Field Observed in a Pilot Study on Pentylenetetrazol - Induced Seizures and Mortality in Mice. Epilepsy Research 2001, 44: 27-32.
47. Canseven AG, Keskil ZA, Keskil İS, Seyhan N. Magnetic Field Alters the Pentylenetetrazol-Induced Seizures on Neither pre-Drug nor Post-Drug Exposure. International Electromagnetic Field (EMF) Project, Workshop: Sensitivity of Children to Electromagnetic Fields. 2004, İstanbul, Turkey, P5.
48. Graham C, Cook MR, Riffle DW. Human Melatonin during Continuous Magnetic Field Exposure. Bioelectromagnetics, 1996; 18: 166-171.
49. Ueno S, Iwasaka M. Magnetic Nerve Stimulation and Effects of Magnetic Fields on Biological, Physical and Chemical Processes. In Ueno S (ed): Biological Effects of Magnetic and Electromagnetic Fields. New York: Plenum Press; 1996. p. 1-22.
50. Canseven AG, Seyhan N, Aydin A, Işimer A. Extremely Low Frequency Electromagnetic Field Effect on Brain Tissue and Blood Plasma Electrolytes. Med & Biol Eng & Comput 1999, 37, Suppl. 2: 1336-1337.
51. Canseven AG, Özel Ü, Bilgihan A, Seyhan N. Myeloperoxidase (MPO) Activities in Brain, Lung and Renal Tissues After Exposure to Magnetic Fields of 50 Hz. 13th Balkan Biochemical Biophysical Days & Meeting on Metabolic Disorders. 2003, Kuşadasi, Turkey, P94.
52. Barnes F. Some Engineering Models for Interactions of Electric and Magnetic Fields with Biological Systems. Bioelectromagnetics 1992, Suppl. 1:67-85.
53. Adey WR, Sheppard AR. Cell Surface Ionic Phenomena in Transmembrane Signalling to Intracellular Enzyme Systems. In Blank M, Findl E (eds): Mechanistic Approaches to Interactions of Electric and Electromagnetic Fields with Living Systems. New York: Plenum Press; 1987. p. 365-388.
54. Polk C. Modification of Charge Distribution at Boundaries between Electrically Dissimilar Media. In Blank M, Findl E (eds): Mechanistic Approaches to Interactions of Electric and Electromagnetic Fields with Living Systems. New York: Plenum Press; 1987. p. 63-78.
55. Adey WR. Collective Properties of Cell Membranes. In Norden B, Ramel C (eds): Interaction Mechanisms of Low-Level Electromagnetic Fields in Living Systems. Great Britain: Oxford Science Publications; 1992. p. 47-77.
56. Blank M. Ionic Processes at Membrane Surfaces: Double Layers in Electrically Stimulated Ion Transport. In Blank M, Findl E (eds): Mechanistic Approaches to Interactions of Electric and Electromagnetic Fields with Living Systems. New York: Plenum Press; 1987. p. 1-14.
57. Pilla A, Kaufman JJ, Ryaby JT. Electrochemical Kinetics at the Cell Membrane: A Physicochemical Link for Electromagnetic Bioeffects. In Blank M, Findl E (eds): Mechanistic Approaches to Interactions of Electric and Electromagnetic Fields with Living Systems. New York: Plenum Press; 1987. p. 39-62.
58. Grattarola M, Caratozzolo F, Chiabrera A. Interaction of ELF Electromagnetic Fields with Cell Membrane Receptors. In Grandolfo M, Michaelson SM, Rindi A. (eds): Biological Effects and Dosimetry of Static and ELF Electromagnetic Fields. New York: Plenum Press; 1985. p. 273-294.
59. Findl E. Membrane Transduction of Low Energy Level Fields and the Ca++ Hypothesis. In Blank M, Findl E (eds): Mechanistic Approaches to Interactions of Electric and Electromagnetic Fields with Living Systems. New York: Plenum Press; 1987. p. 15-38.
60. Blackman CF, Benane SG, House DE. The Influence of Temperature During Electric and Magnetic Field Induced Alteration of Calcium-Ion Releasing from in Vitro Brain Tissue. Bioelectromagnetics 1991; 12: 173-182.
61. Adey WR. ELF Magnetic Fields and Promotion of Cancer: Experimental Studies. In Norden B, Ramel C (eds): Interaction Mechanisms of Low-Level Electromagnetic Fields in Living Systems. Great Britain: Oxford Science Publications; 1992. p. 23-46.
62. Garcia-Sancho J, Montero M, Alvarez J, Fonteriz RI, Sanchez A. Effects of Extremely Low Frequency Electromagnetic Fields on Ion Transport in Several Mammalian Cells, Bioelectromagnetics 1994; 15: 579-588.
63. Polk C, Postow E. Handbook of Biological Effects of Electromagnetic Field, 2nd Ed. USA: CRC Press; 1996.
64. Voth LM. Determination of Lithium, Zinc and Copper in Blood Serum by Flame Microsampling. Varian Instruments at Work, AA-16, 1981.
65. Voth LM. Determination of Calcium and Magnesium in Blood Serum by Automated Flame Microsampling. Varian Instruments at Work, AA-15, 1981.
66. Gmitrova A, Ivanco I, Gmitrov J, Murin M. Biological Effects of Magnetic Field on Laboratory Animals. J. Bioelectricity 1988, 7: 123-124.
67. Eraslan G, Akdoǧan M, Bilgili A, Kanbur M, Şahindokuyucu F. The Effects of an Electromagnetic Field (60-90 Hz and 5 mT) on Blood Electrolyte Levels in Diurnal Rhythm. Turk J Vet Anim Sci 2002; 26: 1243-1247.
68. Eraslan G, Bilgili A, Eşsiz D, Saltaş H. The Effects of an Electromagnetic Field (90 Hz and 5 mT) on Some Blood Electrolyte (Ca, P, Na, K, Cl) Levels in Male Mice. Turk J Vet Anim Sci 2002; 26: 1233-1236.
69. Cserr H. Biology of the Blood-Brain Barrier. Grass Calendar for 1989, Grass Instrument Co., 1988.
70. Öztürk G, Erbaş D, İmir T, Bor N. Decreased Natural Killer (NK) Cell Activity in Zinc-Deficient Rats. General Pharmacology 1994; 25: 1499-1503.