The nitric oxide donor DETA-NONOate decreases matrix metalloproteinase-9 expression and activity in rat aortic smooth muscle and abdominal aortic explants

Annals of Vascular Surgery

Volumn 20, Issue 1, 2006, Pages 92-98

  Sinha, Indranil ^a   Hannawa, Kevin K ^a   Ailawadi, Gorav ^a   Woodrum, Derek T ^a   Ford, John W ^a   Henke, Peter K ^a   Stanley, James C ^a   Eagleton, Matthew J ^a   Upchurch Jr , Gilbert R ^a,b  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MICHIGAN HOSPITALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

(2,2 HYDROXYNITROSOHYDRAZINO)BIS ETHANAMININE; GELATINASE A; GELATINASE B; INTERLEUKIN 1BETA; MESSENGER RNA; NITRIC OXIDE DONOR; TISSUE INHIBITOR OF METALLOPROTEINASE 1; UNCLASSIFIED DRUG;

ABDOMINAL AORTA; ANALYSIS OF VARIANCE; ANIMAL CELL; ANIMAL TISSUE; AORTA; ARTICLE; CONCENTRATION (PARAMETERS); CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVITY; EXPLANT; IN VITRO STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; SMOOTH MUSCLE; SMOOTH MUSCLE FIBER; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; ZYMOGRAPHY;

EID: 29744449513     PISSN: 08905096     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10016-005-9429-1     Document Type: Article

References (32)

1. Eagleton MJ, Peterson DA, Sullivan MD, et al. Nitric oxide inhibition increases aortic wall matrix metalloproteinase-9 expression. J Surg Res 2002;104:15.
2. Numagachi K, Egashira K, Takemoto M, et al. Chronic inhibition of nitric oxide synthesis causes coronary microvascular remodeling in rats. Hypertension 1995;26:957.
3. Langille BL, O'Donnell F. Reductions in arterial diameter produced by chronic decreases in blood flow are endothelium dependant. Science 1986;231:405.
4. Rudic RD, Shesely EG, Maeda N, Smithies O, Segal SS, Sessa NC. Direct evidence for the importance of endothelium derived nitric oxide in vascular remodeling. J Clin Invest 1998;101:731.
5. Tronc F, Wassef M, Esposito B, Henrion D, Glagsov S, Tedqui A. Role of NO in flow-induced remodeling of the rabbit common carotid artery. Arterioscler Thromb Vasc Biol 1996;16:1256.
6. Upchurch GR, Ford JW, Weiss SJ, et al. Nitric oxide inhibition increases metalloprotienase-9 expression by rat aortic smooth muscle cells in vitro. J Vasc Surg 2001;34:76.
7. Curci JA, Liao S, Huffman MD, Shapiro SD, Thompson RW. Expression and localization of macrophage elastase (matrix metalloproteinase-12) in abdominal aortic aneurysms. J Clin Invest 1998;102:1900.
8. Sinha I, Hannawa KK, Eliason JL, et al. Early MT-1 MMP expression following elastase exposure is associated with increased cleaved MMP-2 activity in experimental rodent aortic aneurysms. Surgery 2004;136:176-182.
9. Freestone T, Turner RJ, Coady A, Higman DJ, Greenhalgh RM, Powell JT. Inflammation and matrix metalloproteinases in the enlarging abdominal aortic aneurysm. Arterioscler Thromb Vasc Biol 1995;15:1145.
10. Herron GS, Unemori E, Wong M, Rapp JH, Hibbs SM, Stony RJ. Connective tissue proteinases and inhibitors in abdominal aortic aneurysms: involvement of the vaso vasorum in the pathogenesis of aortic aneurysms. Arterioscler Thromb Vasc Biol 1991;11:1667.
11. McMillan WD, Patterson BK, Keen RR, Pearce WH. In situ localization and quantification of 72 kD type IV collagenase in aneurysmal, occlusive, and normal aorta. J Vasc Surg 1995;22:295.
12. McMillan WD, Patterson BK, Keen RR, Shively VP, Cipollone M, Pearce WH. In situ localization and quantification of mRNA for 92 kD type IV collagenase and its inhibitor in aneurysmal, occlusive, and normal aorta. Arterioscler Thromb Vasc Biol 1995;15:1139.
13. Newman KM, Ogata Y, Malon AM, et al. Identification of metalloproteinase-3 (stromelysin-1) and -9 (gelatinase B) in abdominal aortic aneurysm. Arterioscler Thromb Vasc Biol 1994;14:1315.
14. Pyo R, Lee JK, Shipley M, et al. Targeted gene disruption of matrix metalloprotienase-9 (gelatinase B) suppresses development of experimental abdominal aortic aneurysms. J Clin Invest 2000;105:1641.
15. Tamarina NA, McMillan WD, Shively VP, Pearce WH. Expression of matrix metalloproteinases and their inhibitors in aneurysms and normal aorta. Surgery 1997;122. 264.
16. Thompson RW, Holmes DR, Mertens RA, et al. Production and localization of 92 kD gelatinase in abdominal aortic aneurysms: an elastolytic metalloproteinase expressed by aneurysm infiltrating macrophages. J Clin Invest 1995;96. 318.
17. Yamashita A, Noma T, Nakazawa A, et al. Enhanced expression of metalloproteinase-9 in abdominal aortic aneurysms. World J Surg 2001;25:259.
18. Longo MG, Xiong W, Greiner TC, Zhao Y, Fiotti N, Baxter TB. Matrix metalloproteinases 2 and 9 work in concert to produce aortic aneurysms. J Clin Invest 2002;110:625.
19. Bendeck MP. Matrix metalloproteinases: are they antiatherogenic but proaneurysmal? Circ Res 2002;90:836.
20. Lee JK, Borhani M, Ennis TL, Upchurch GR, Thompson RW. Experimental abdominal aortic aneurysms in mice lacking expression of inducible nitric oxide synthase. Arterioscler Thromb Vasc Biol 2001;21:1393.
21. Davis VA, Persidskaia RN, Baca-Regen LM, Fiotti N, Halloran BG, Baxter BT. Cytokine pattern in aneurysmal and occlusive disease of the aorta. J Surg Res 2001;101:152.
22. Gurjar MV, Sharma RV, Bhalla RC. eNOS gene transfer inhibits smooth muscle cell migration and MMP-2 and MMP-9 activity. Arterioscler Thromb Vasc Biol 1999;19:2871.
23. Knipp BS, Ailawadi G, Ford JW, et al. Increased MMP-9 expression and activity by aortic smooth muscle cells after nitric oxide synthase inhibition is associated with increased nuclear factor-kappaB and activator protein-1 activity. J Surg Res 2004;116:70.
24. Paik D, Tilson MD. Neovascularization in the abdominal aortic aneurysm. Endothelial nitric oxide synthase, nitric oxide and elastolysis. Ann N Y Acad Sci 1996;800:277.
25. Knipp B, Peterson DA, Rajagopalan S, et al. Impaired vasoreactivity despite an increase in plasma nitrite in patients with abdominal aortic aneurysms. J Vasc Surg 2002;35:363.
26. Troxler M, Naseem KM, Homer-Vanniasinkam S. Increased nitrotyrosine production in patients undergoing abdominal aortic aneurysm repair. Br J Surg 2004;91:1146.
27. Khurana VG, Sohni YR, Mangrum WI, et al. Endothelial nitric oxide synthase gene polymorphisms predict susceptibility to aneurismal subarachnoid hemorrhage and cerebral vasospasm. J Cereb Blood Flow Metab 2004;24:291.
28. Khurana VG, Sohni YR, Mangrum WI, et al. Endothelial nitric oxide synthase T-786C single nucleotide polymorphism. Stroke 2003;34:2555.
29. Yajima N, Masuda M, Miyazaki M, Nakajima N, Chien S, Shyy J. Oxidative stress is involved in the development of experimental abdominal aortic aneurysm: a study of the transcription profile with complementary DNA microarray. J Vasc Surg 2002;36:279.
30. Johanning JM, Armstrong PJ, Franklin DP, Han DC, Carey DJ, Elmore JR. Nitric oxide in experimental aneurysm formation: early events and consequences of nitric oxide inhibition. Ann Vasc Surg 2002;26:65.
31. Johanning JM, Franklin DP, Han DC, Carey DJ, Elmore JR. Inhibition of inducible nitric oxide synthesis limits nitric oxide production and experimental aneurysm formation. J Vasc Surg 2001;24:579.
32. Gurjar MV, DeLeon J, Sharma RV, Bhalla RC. Mechanism of inhibition of matrix metalloproteinase-9 induction by NO in vascular smooth muscle cells. J Appl Physiol 2001;91:1380-1386.