Early life trauma decreases glucocorticoid receptors in rat dentate gyrus upon adult re-stress: Reversal by escitalopram

Neuroscience

Volumn 137, Issue 2, 2006, Pages 619-625

  Uys, J D K ^a   Muller, C J F ^a   Marais, L ^a   Harvey, B H ^b   Stein, D J ^c   Daniels, W M U ^a  

^a STELLENBOSCH UNIVERSITY   (South Africa)

^b NORTH WEST UNIVERSITY   (South Africa)

^c UNIVERSITY OF CAPE TOWN   (South Africa)

Author keywords

Corticosterone; Hippocampus; Immunohistochemistry; SSRI; Trauma

Indexed keywords

CORTICOSTERONE; ESCITALOPRAM; GLUCOCORTICOID RECEPTOR; SEROTONIN UPTAKE INHIBITOR;

ANIMAL TISSUE; ARTICLE; BLOOD SAMPLING; BRAIN REGION; CONTROLLED STUDY; CORTICOSTERONE BLOOD LEVEL; DENTATE GYRUS; GRANULE CELL; HYPOPHYSIS ADRENAL SYSTEM; HYPOTHALAMUS; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MALE; NONHUMAN; OSMOTIC MINIPUMP; PERINATAL PERIOD; PRIORITY JOURNAL; RAT; SWIMMING;

AGING; ANIMALS; CITALOPRAM; DENTATE GYRUS; DISEASE MODELS, ANIMAL; DOWN-REGULATION; GLUCOCORTICOIDS; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; MALE; NEURONS; PITUITARY-ADRENAL SYSTEM; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GLUCOCORTICOID; SEROTONIN; SEROTONIN UPTAKE INHIBITORS; STRESS DISORDERS, POST-TRAUMATIC; STRESS, PSYCHOLOGICAL;

EID: 29744443778     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2005.08.089     Document Type: Article

References (38)

1. L. Bjartmar, I.M. Johansson, J. Marcusson, S.B. Ross, J.R. Seckl, T. Olsson Selective effects on NGFI-A, MR, GR and NGFI-B hippocampal mRNA expression after chronic treatment with different subclasses of antidepressants in the rat Psychopharmacology 151 1 2000 7 12
2. O. Bonne, Y. Krausz, Y. Aharon, Y. Gelfin, R. Chisin, B. Lerer Clinical doses of fluoxetine and cerebral blood flow in healthy volunteers Psychopharmacology 143 1 1999 24 28
3. L.S. Brady, P.W. Gold, M. Herkenham, A.B. Lynn, H.J. Whitfield Jr The antidepressants fluoxetine, idazoxan and phenelzine alter corticotropin- releasing hormone and tyrosine hydroxylase mRNA levels in rat brain therapeutic implications Brain Res 572 1-2 1992 117 125
4. B. Budziszewska, J. Siwanowicz, E. Przegalinski The effect of chronic treatment with antidepressant drugs on the corticosteroid receptor levels in the rat hippocampus Pol J Pharmacol 46 3 1994 147 152
5. W.J. Cassano Jr, A.P. D'mello Acute stress-induced facilitation of the hypothalamic-pituitary-adrenal axis evidence for the roles of stressor duration and serotonin Neuroendocrinology 74 2001 167 177
6. B. Czeh, T. Michaelis, T. Watanabe, J. Frahm, G. de Buirrun, M. van Kampen, A. Bartolomucci, E. Fuchs Stress-induced changes in cerebral metabolites, hippocampal volume, and cell proliferation are prevented by the antidepressant treatment with tianeptine Proc Natl Acad Sci USA 98 2001 12796 12801
7. B. Czeh, T. Welt, A.K. Fischer, A. Erhardt, W. Schmitt, M.B. Muller, N. Toschi, E. Fuchs, M.E. Keck Chronic psychosocial stress and concomitant repetitive transcranial magnetic stimulation effects on stress hormone levels and adult hippocampal neurogenesis Biol Psychiatry 52 2002 1057 1065
8. W.C. Drevets Neuroimaging abnormalities in the amygdala in mood disorders Ann N Y Acad Sci 985 2003 420 444
9. R.S. Duman, G.R. Heninger, E.J. Nestler A molecular and cellular theory of depression Arch Gen Psychiatry 54 1997 597 606
10. R.S. Duman, J. Malberg, J. Thome Neural plasticity to stress and anti-depressant treatment Biol Psychiatry 44 1999 324 335
11. E.W. Fish, S. Faccidomo, S. Gupta, K.A. Miczek Anxiolytic-like effects of escitalopram, citalopram, and R-citalopram in maternally separated mouse pups J Pharmacol Exp Ther 308 2 2004 474 480
12. Y. Gelfin, M. Gorfine, B. Lerer Effect of clinical doses of fluoxetine on psychological variables in healthy volunteers Am J Psychiatry 155 2 1998 290 292
13. R. Grossman, M.S. Buchsbuam, R. Yehuda Neuroimaging studies in post-traumatic stress disorder Psychiatr Clin North Am 25 2002 317 340
14. 1A/2A receptor changes evoked by a time-dependent sensitisation (TDS) stress model in rats Brain Res 938 2003 97 107
15. B.H. Harvey, C. Naciti, L. Brand, D.J. Stein Serotonin and stress protective or malevolent actions in the biobehavioral response to repeated trauma? Ann N Y Acad Sci 1032 2004 267 272
16. C. Heim, C.B. Nemeroff The role of childhood trauma in the neurobiology of mood and anxiety disorders preclinical and clinical studies Biol Psychiatry 49 2001 1023 1039
17. M. Hery, A. Semont, M.P. Fache, M. Faudon, F. Hery The effects of serotonin on glucocorticoid receptor binding in rat raphe nuclei and hippocampal cells in culture J Neurochem 74 1 2000 406 413
18. A.M. Hull Neuroimaging findings in post-traumatic stress disorder systematic review Br J Psychiatry 181 2002 102 110
19. Y.J. Karten, S.M. Nair, L. van Essen, R. Sibug, M. Joels Long-term exposure to high corticosterone levels attenuates serotonin responses in rat hippocampal CA1 neurons Proc Natl Acad Sci USA 96 1999 13456 13461
20. J. Kaufman, P.M. Plotsky, C.B. Nemeroff, D.S. Charney Effects of early adverse experiences on brain structure and function clinical implications Biol Psychiatry 48 2000 778 790
21. K.S. Kendler, M.C. Neale, R.C. Kessler, A.C. Heath, L.J. Eaves Childhood parental loss and adult psychopathology in women. A twin study perspective Arch Gen Psychiatry 49 2 1992 109 116
22. D.G. Kim, S. Lee, J.S. Lim Neonatal footshock stress alters adult behavior and hippocampal corticosteroid receptors Neuroreport 10 12 1999 2551 2556
23. C.O. Ladd, R.L. Huot, K.V. Thrivikraman, C.B. Nemeroff, P.M. Plotsky Long-term adaptations in glucocorticoid receptor and mineralocorticoid receptor mRNA and negative feedback on the hypothalamo-pituitary-adrenal axis following neonatal maternal separation Biol Psychiatry 55 4 2004 367 375
24. V. Lemaire, M. Koehl, M. Le Moal, D.N. Abrous Prenatal stress produced learning deficits associated with an inhibition of neurogenesis in the hippocampus Proc Natl Acad Sci USA 97 2000 11032 11037
25. I. Liberzon, M. Krstov, E.A. Young Stress-restress effects on ACTH and fast feedback Psychoneuroendocrinology 26 1997 443 453
26. J.E. Malberg, A.J. Eisch, E.J. Nestler, R.S. Duman Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus J Neurosci 20 24 2000 9104 9110
27. B.S. McEwen Stress and hippocampal plasticity Annu Rev Neurosci 22 1999 105 122
28. B.S. McEwen Effects of adverse experiences for brain structure and function Biol Psychiatry 48 8 2000 721 731
29. H.S. Nadeem, M.J. Attenburrow, P.J. Cowen Comparison of the effects of citalopram and escitalopram on 5-Ht-mediated neuroendocrine responses Neuropsychopharmacology 29 9 2004 1699 1703
30. G. Paxinos, C. Watson The rat brain on stereotaxic co-ordinates 2nd ed. 1986 Academic Press San Diego, USA
31. C. Sanchez, P.B. Bergqvist, L.T. Brennum, S. Gupta, S. Hogg, A. Larsen, O. Wiborg Escitalopram, the S-(+)-enantiomer of citalopram, is a selective serotonin reuptake inhibitor with potent effects in animal models predictive of antidepressant and anxiolytic activities Psychopharmacology 167 2003 353 362
32. C. Sanchez, M. Kreilgaard R-citalopram inhibits functional and 5-HTP-evoked behavioural responses to the SSRI, escitalopram Pharmacol Biochem Behav 77 2 2004 391 398
33. J.R. Seckl, G. Fink Antidepressants increase glucocorticoid and mineralocorticoid receptor mRNA expression in rat hippocampus in vivo Neuroendocrinology 55 6 1992 621 626
34. D.M. Vazquez, H. Van Oers, S. Levine, H. Akil Regulation of glucocorticoid and mineralocorticoid receptor mRNAs in the hippocampus of the maternally deprived infant rat Brain Res 731 1-2 1996 79 90
35. J.O. Workel, M.S. Oitzl, M. Fluttert, H. Lesscher, A. Karssen, E.R. de Kloet Differential and age-dependent effects of maternal deprivation on the hypothalamic-pituitary-adrenal axis of brown Norway rats from youth to senescence J Neuroendocrinol 13 7 2001 569 580
36. J.L. Yau, C. Hibberd, J. Noble, J.R. Seckl The effect of chronic fluoxetine treatment on brain corticosteroid receptor mRNA expression and spatial memory in young and aged rats Brain Res Mol Brain Res 106 1-2 2002 117 123
37. R.Y. Yehuda, S.M. Antelman Criteria for rationally evaluating animal models of posttraumatic stress disorder Biol Psychiatry 33 1993 479 486
38. R. Yehuda Biology of posttraumatic stress disorder J Clin Psychiatry 62 Suppl 17 2001 41 46