CD4+ T lymphocytes expressing CD40 ligand help the IgM antibody response to soluble pneumococcal polysaccharides via an intermediate cell type

Journal of Immunology

Volumn 176, Issue 1, 2006, Pages 529-536

  Jeurissen, Axel ^a   Billiau, An D ^b   Moens, Leen ^a   Shengqiao, Li ^b   Landuyt, Willy ^c   Wuyts, Greet ^a   Boon, Louis ^d   Waer, Mark ^b   Ceuppens, Jan L ^c   Bossuyt, Xavier ^a,c  

^a Laboratory of Experimental Laboratory Medicine   (Belgium)

^b UNIVERSITY OF LEUVEN   (Belgium)

^c UNIVERSITY HOSPITALS LEUVEN   (Belgium)

^d BIOCEROS   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CD40 ANTIGEN; CD40 LIGAND; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN M ANTIBODY; PNEUMOCOCCUS POLYSACCHARIDE; PNEUMOCOCCUS VACCINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY RESPONSE; ANTIGEN PRESENTING CELL; ARTICLE; B LYMPHOCYTE; BONE MARROW TRANSPLANTATION; CD4+ T LYMPHOCYTE; CELL TYPE; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; HEMATOPOIETIC CELL; KNOCKOUT MOUSE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SCID MOUSE; SPLEEN CELL; STREPTOCOCCUS PNEUMONIAE;

EID: 29644448059     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.176.1.529     Document Type: Article

References (29)

1. Musher, D. M. 1992. Infection caused by Streptococcus pneumoniae: clinical spectrum, pathogenesis, immunity, and treatment. Clin. Inf. Dis. 14: 801-809.
2. Bruyn, G. A., B. J. Zegers, and R. Van Furth. 1992. Mechanisms of host defense against infection with Streptococcus pneumoniae. Clin. Inf. Dis. 14: 251-262.
3. Mond, J. J., A. Lees, and C. M. Snapper. 1995. T cell-independent antigens type 2. Anna. Rev. Immunol. 13: 655-692.
4. Jeurissen, A., and X. Bossuyt. 2004. T cell-dependent and -independent responses. J. Immunol. 172: 2728-2729.
5. Foy, T. M., D. M. Shepherd, F. H. Durie, A. Aruffo, J. A. Ledbetter, and R. J. Noelle. 1993. In vivo CD40-gp39 interactions are essential for thymus-dependent humoral immunity. II. Prolonged suppression of the humoral immune response by an antibody to the ligand for CD40, gp39. J. Exp. Med. 178: 1567-1575.
6. Renshaw, B. R., W. C. Fanslow, R. J. Armitage, K. A. Campbell, D. Liggitt, B. Wright, B. L. Davison, and R. Maliszewski. 1994. Humoral immune responses in CD40 ligand-deficient mice. J. Exp. Med. 180: 1889-1900.
7. Kawabe, T., T. Naka, K. Yoshida, T. Tanaka, H. Fujiwara, S. Suematsu, N. Yoshida, T. Kishimoto, and H. Kikutani. 1994. The immune responses in CD40-deficient mice: impaired immunoglobulin class switching and germinal center formation. Immunity 1: 167-178.
8. Hwang, Y., M. H. Nahm, D. E. Briles, D. Thomas, and J. M. Purkerson. 2000. Acquired, but not innate, immune responses to Streptococcus pneumoniae are compromised by neutralization of CD40L. Infect. Immun. 68: 511-517.
9. Jeurissen, A., M. Wuyts, A. Kasran, S. Murli-Ramdien, L. Boon, J. L. Ceuppens, and X. Bossuyt. 2002. Essential role for CD40 ligand interactions in T lymphocyte mediated modulation of the murine immune response to pneumococcal capsular polysaccharides. J. Immunol. 168: 2773-2781.
10. Jeurissen, A., G. Wuyts, A. Kasran, S. Ramdien-Murli, N. Blanckaert, L. Boon, J. L. Ceuppens, and X. Bossuyt. 2004. The human antibody response to pneumococcal capsular polysaccharides is dependent on the CD40-CD40L interaction. Eur. J. Immunol. 34: 850-858.
11. 4+ T cell help. J. Immunol. 172: 532-539.
12. Steinsvik, T. E., P. I. Gaarder, I. S. Aaberge, and M. Lovik. 1995. Engraftment and humoral immunity in SCID and RAG-2-deficient mice transplanted with human peripheral blood lymphocytes. Scand. J. Immunol. 42: 607-613.
13. Shlomchik, W. D., M. S. Couzens, C. B. Tang, J. McNiff, M. E. Robert, J. Liu, M. J. Shlomchik, and S. G. Emerson. 1999. Prevention of graft versus host disease by inactivation of host antigen-presenting cells. Science 285: 412-415.
14. Krasinskas, A. M., S. D. Eiref, A.D. McLean, D. Kreisel, A. E. Gelman, S. H. Popma, J. S. Moore, and B. R. Rosengard. 2000. Replacement of graft-resident donor-type antigen presenting cells alters the tempo and pathogenesis of murine cardiac allograft rejection. Transplantation 70: 514-521.
15. Ada, G. 2001. Vaccines and vaccination. N. Engl. J. Med. 345: 1042-1053.
16. Wasserman, R. L., and R. U. Sorensen. 1999. Evaluating children with respiratory tract infections: the role of immunization with bacterial polysaccharide vaccine. Pediatr. Infect. Dis. J. 18: 157-163.
17. Xu, J., T. M. Foy, J. D. Laman, E. A. Elliott, J. J. Dunn, T. J. Waldschmidt, J. Elsemore, R. J. Noelle, and R. A. Flavell. 1994. Mice deficient for the CD40 ligand. Immunity 1: 423-431.
18. Van den Eertwegh, A. J., R. J. Noelle, M. Roy, D. M. Shepherd, A. Aruffo, J. A. Ledbetter, W. J. Boersma, and E. Claassen. 1993. In vivo CD40-gp39 interactions are essential for thymus-dependent humoral immunity. I. In vivo expression of CD40 ligand, cytokines, and antibody production delineates sites of cognate T-B cell interactions. J. Exp. Med. 178: 1555-1565.
19. Castigli, E., F. W. Alt, L. Davidson, A. Bottaro, E. Mizoguchi, A. K. Bhan, and R. S. Geha. 1994. CD40-deficient mice generated by recombination-activating gene-2-deficient blastocyst complementation. Proc. Natl. Acad. Sci. USA 91: 12135-12139.
20. Baker, P. J. 1992. Immune responses to Haemophilus influenzae type b polysaccharide: T cell regulation of the antibody response to bacterial polysaccharide antigens: an examination of some general characteristics and their implications. J. Infect. Dis. 165: S44-S48.
21. Baker, P. J., and T. Hraba. 1994. T-cell mediated immunosuppression and its implications for the development of protective immunity. Folia Biol. 40: 349-358.
22. Manning, J., N. D. Reed, and J. W. Jutila. 1972. Antibody response to Escherichia coli lipopolysaccharide ant type III pneumococcal polysaccharide by congenitally thymusless (nude) mice. J. Immunol. 108: 1470-142.
23. Griffioen, A. W., G. T. Rijkers, E. A. Toebes, and B. J. Zegers. 1991. The human in vitro anti-type 4 pneumoccoccal polysaccharide antibody response is regulated by suppressor T cells. Scand. J. Immunol. 34: 229-236.
24. Griffioen, A. W., E. A. Toebes, G. T. Rijkers, F. H. Claas, G. Datema, and B. J. Zegers. 1992. The amplifier role of T cells in the human in vitro B cell response to type 4 pneumococcal polysaccharide. Immunol. Lett. 32: 265-272.
25. Bondada, S., H. Wu, D. A. Robertson, and R. L. Chelvarajan. 2001. Accessory cell defect in unresponsiveness of neonates and aged to polysaccharide vaccines. Vaccine 19: 557-565.
26. Colino, J., Y. Shen, and C. M. Snapper. 2002. Dendritic cells pulsed with intact Streptococcus pneumoniae elicit both protein-and polysaccharide-specific immunoglobulin isotype responses in vivo through distinct mutations. J. Exp. Med. 195: 1-13.
27. Garcia de Vinuesa, C., I. C. MacLennan, M. Holman, and G. B. Klaus. 1999. Anti-CD40 antibody enhances response to polysaccharide without mimicking T cell help. Eur. J. Immunol. 29: 3216-3224.
28. Garg, M., A. M. Kaplan, and S. Bondada. 1994. Cellular basis of differential responsiveness of lymph nodes and spleen to 23-valent pneu-immune vaccine. J. Immunol. 152: 1589-1596.
29. Bondada, S., H. Wu, D. A. Robertson, and R. L. Chelvarajan. 2001. Accessory cell defect in unresponsiveness of neonates and aged to polysaccharide vaccines. Vaccine 19: 557-565.