Heterozygous disruption of SERCA2a is not associated with impairment of cardiac performance in humans: Implications for SERCA2a as a therapeutic target in heart failure

Heart

Volumn 92, Issue 1, 2006, Pages 105-109

  Mayosi, B M ^a,b,c   Kardos, A ^b   Davies, C H ^b,f   Gumedze, F ^c   Hovnanian, A ^d   Burge, S ^e   Watkins, Hugh ^a,b  

^a JOHN RADCLIFFE HOSPITAL   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c UNIVERSITY OF CAPE TOWN   (South Africa)

^d CHU PURPAN   (France)

^e CHURCHILL HOSPITAL   (United Kingdom)

^f OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE (CALCIUM); CALCIUM ADENOSINE TRIPHOSPHATASE 2A; UNCLASSIFIED DRUG;

ADULT; ARTICLE; AUTOSOMAL DOMINANT DISORDER; CONGESTIVE CARDIOMYOPATHY; CONTROLLED STUDY; DARIER DISEASE; DIASTOLIC BLOOD PRESSURE; DISEASE ASSOCIATION; DRUG TARGETING; ECHOCARDIOGRAPHY; ENZYME DEFICIENCY; EXERCISE; EXPECTATION; FEMALE; FUNCTIONAL ASSESSMENT; GENE DISRUPTION; GENE MUTATION; GENETIC CODE; HEART FAILURE; HEART MUSCLE CONTRACTILITY; HEART PERFORMANCE; HETEROZYGOTE; HUMAN; MALE; PRIORITY JOURNAL; REST; RODENT; SARCOPLASMIC RETICULUM; SYSTOLIC BLOOD PRESSURE;

CALCIUM-TRANSPORTING ATPASES; CARDIOMYOPATHY, DILATED; CASE-CONTROL STUDIES; EXERCISE TOLERANCE; FEMALE; GENE THERAPY; HEART FAILURE, CONGESTIVE; HETEROZYGOTE; HUMANS; KERATOSIS FOLLICULARIS; MALE; MIDDLE AGED; MUTATION; SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES;

EID: 29644442273     PISSN: 13556037     EISSN: None     Source Type: Journal    
DOI: 10.1136/hrt.2004.051037     Document Type: Article

References (26)

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