Genome-wide linkage scan for spontaneous DZ twinning

European Journal of Human Genetics

Volumn 14, Issue 1, 2006, Pages 117-122

  Derom, Catherine ^a   Jawaheer, Damini ^b   Chen, Wei V ^c   McBride, Kim L ^d   Xiao, Xiangli ^b   Amos, Chris ^c   Gregersen, Peter K ^b   Vlietinck, Robert ^a  

^a UNIVERSITY HOSPITALS LEUVEN   (Belgium)

^b Department of Medicine   (United States)

^c UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^d OHIO STATE UNIVERSITY   (United States)

Author keywords

Candidate genes; DZ twins; Linkage; Twinning frequency

Indexed keywords

ARTICLE; AUTOSOMAL DOMINANT INHERITANCE; CHROMOSOME 18; CHROMOSOME 2; CHROMOSOME 7; FAMILY; FEMALE; GENE FREQUENCY; GENETIC ANALYSIS; GENETIC HETEROGENEITY; GENETIC LINKAGE; GENETIC MODEL; GENETIC SUSCEPTIBILITY; HAPLOTYPE; HUMAN; PHENOTYPE; PRIORITY JOURNAL; SCORING SYSTEM; TWIN PREGNANCY; TWINS; ZYGOSITY;

BELGIUM; CHROMOSOMES, HUMAN; FEMALE; GENES, DOMINANT; GENOME, HUMAN; HUMANS; LINKAGE (GENETICS); LOD SCORE; MALE; MATERNAL AGE; MODELS, GENETIC; TWINS, DIZYGOTIC;

EID: 29644442189     PISSN: 10184813     EISSN: 14765438     Source Type: Journal    
DOI: 10.1038/sj.ejhg.5201522     Document Type: Article

References (27)

1. Montgomery GW, Crawford AM, Penty JM et al: The ovine Booroola fecundity gene (FecB) is linked to markers from a region of human chromosome 4q. Nat Genet 1993; 4: 410-414.
2. Davis GH, McEwan JC, Fennessy PF, Dodds KG, Farquhar PA: Evidence for the presence of a major gene influencing ovulation rate on the X chromosome of sheep. Biol Reprod 1991; 44: 620-624.
3. Lewis CM, Healey SC, Martin NG: Genetic contribution to DZ twinning. Am J Med Genet 1996; 61: 237-246.
4. Bulmer MG: The Biology of Twinning in Man. Oxford: Clarendon, 1970.
5. Meulemans WJ, Lewis CM, Boomsma DI et al: Genetic modelling of dizygotic twinning in pedigrees of spontaneous dizygotic twins. Am J Med Genet 1996; 61: 258-263.
6. Meulemans WJ, Lewis CM, Boomsma DI et al: Segregation analysis of dizygotic twinning in pedigrees of dizygotic twins conceived after artificial induction of ovulation. Am J Hum Genet 1994; 55: A158.
7. Loos R, Derom C, Vlietinck R et al: The East Flanders Prospective Twin Survey (Belgium): A population-based register. Twin Res 1998; 1: 167-175.
8. Peeters H, Van Gestel S, Vlietinck R et al: Validation of a telephone zygosity questionnaire in twins of known zygosity. Behav Genet 1998; 28: 159-163.
9. Jawaheer D, Seldin MF, Amos CI et al: A genomewide screen in multiplex rheumatoid arthritis families suggests genetic overlap with other autoimmune diseases. Am J Hum Genet 2001; 68: 927-936.
10. Ott J: Computer-simulation methods in human linkage analysis. Proc Natl Acad Sci USA 1989; 86: 4175-4178.
11. WAeks D, Ott J, Lathrop G: SLINK: a general simulation program for linkage analysis. Am J Hum Genet 1990; 47: A204.
12. Sobel E, Lange K: Descent graphA in pedigree analysis: applications to haplotyping, location scores, and marker-sharing statistics. Am J Hum Genet 1996; 58: 1323-1337.
13. Montgomery GW, Duffy DL, Hall J et al: Mutations in the follicle-stimulating hormone receptor and familial dizygotic twinning. Lancet 2001; 357: 773-774.
14. Göring H, Ott J: Verification of sib relationship without knowledge of parental genotypes. Am J Hum Genet 1995; 57: A192.
15. Gilfillan CP, Robertson DM, Burger HG et al: The control of ovulation in mothers of dizygotic twins. J Clin Endocrinol Metab 1996; 81: 1557-1562.
16. Nylander PP: Serum levels of gonadotrophins in relation to multiple pregnancy in Nigeria. J Obstet Gynaecol Br Commonw 1973; 80: 651-653.
17. Lockwood GM, Muttukrishna S, Ledger WL: Inhibins and activins in human ovulation, conception and pregnancy. Hum Reprod Update 1998; 4: 284-295.
18. Busjahn A, Knoblauch H, Faulhaber HD et al: A region on chromosome 3 is linked to dizygotic twinning. Nat Genet 2000; 26: 398-399.
19. Hasbargen U, Lohse P, Thaler CJ: The number of dichorionic twin pregnancies is reduced by the common MTHFR 677C→T mutation. Hum Reprod 2000; 15: 2659-2662.
20. Fabre S, Pierre A, Pisselet C et al: The Booroola mutation in sheep is associated with an alteration of the bone morphogenetic protein receptor-IB functionality. J Endocrinol 2003; 177: 435-444.
21. Mukhopadhyay N, Almasy L, Schroeder M, Mulvihill W, DE W: Mega2, a data-handling program for facilitating genetic linkage and association analyses. Am J Hum Genet 1999; 65: A436.
22. Ott J: Analysis of Human Genetic Linkage. Baltimore: Johns Hopkins University Press, 1999.
23. Derom C, Groenen P, Vlietinck R: Follicle-stimulating-hormone receptor and twinning. Lancet 2001; 357: 230-231, author reply 231-232.
24. Duffy D, Montgomery G, Treloar S et al: IBD sharing around the PPARG locus is not increased in dizygotic twins or their mothers. Nat Genet 2001; 28: 315.
25. Montgomery GW, Zhao ZZ, Morley KI et al: Dizygotic twinning is not associated with methylenetetrahydrofolate reductase haplotypes. Hum Reprod 2003; 18: 2460-2464.
26. Dizier MH, Babron MC, Clerget-Darpoux F: Conclusion of LODscore analysis for family data generated under two-locus models. Am J Hum Genet 1996; 58: 1338-1346.
27. Campbell D: Natural factors influencing multiple gestation; in Blickstein I, Eeith LG (eds): Multiple pregnancy: epidemiology, gestation & perinatal outcome. London: New York, Taylor & Francis, 2005, pp 87-93.