Design, synthesis, and anti-Helicobacter pylori activity of erythromycin A (E)-9-oxime ether derivatives

Bioorganic and Medicinal Chemistry Letters

Volumn 16, Issue 3, 2006, Pages 569-572

  Nam, Ghilsoo ^a   Kang, Tae Won ^b   Shin, Jung Hyu ^c   Choi, Kyung Il ^a  

^a Korea Institute of Science and Technology   (South Korea)

^b Chong Kun Dang Research Institute   (South Korea)

^c Seoul National University   (South Korea)

Author keywords

Acid stability; Anti Helicobacter pylori; Erythromycin; MIC; Oxime ether

Indexed keywords

ACID; CLARITHROMYCIN; ERYTHROMYCIN DERIVATIVE; OXIME DERIVATIVE;

ANTIBACTERIAL ACTIVITY; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG SCREENING; DRUG SYNTHESIS; HELICOBACTER PYLORI; IN VITRO STUDY; MASS SPECTROMETRY; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE;

ANTI-BACTERIAL AGENTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CLARITHROMYCIN; DRUG DESIGN; ERYTHROMYCIN; ETHERS; GASTROINTESTINAL AGENTS; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; MICROBIAL SENSITIVITY TESTS; MODELS, CHEMICAL; OXIMES;

HELICOBACTER PYLORI;

EID: 29644436528     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.10.045     Document Type: Article

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17. +).
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19. 18C column was used and the dual detector wavelength was 210 and 245 nm.