Cytomegalovirus infection after autologous stem cell transplantation: Incidence and outcome in a group of patients undergoing a surveillance program

Transplant Infectious Disease

Volumn 7, Issue 3-4, 2005, Pages 122-125

  Rossini, Fausto ^a   Terruzzi, E ^a   Cammarota, S ^a   Morini, F ^a   Fumagalli, M ^a   Verga, L ^a   Elli, E ^a   Verga, M ^a   Miccolis, I ^a   Parma, M ^a   Pogliani, E M ^a  

^a SAN GERARDO HOSPITAL   (Italy)

Author keywords

Autologous stem cell transplantation; Cytomegalovirus; Immunocompromised host; Myeloma; Non Hodgkin's lymphoma

Indexed keywords

AMIKACIN; ANTIBIOTIC AGENT; ANTIVIRUS AGENT; CEFTRIAXONE; CIDOFOVIR; CREATININE; GANCICLOVIR; PROBENECID; VALGANCICLOVIR; VIRUS ANTIGEN;

ACUTE LEUKEMIA; ANTIBIOTIC THERAPY; ANTIGEN DETECTION; ANURIA; ARTICLE; AUTOLOGOUS STEM CELL TRANSPLANTATION; CAUSE OF DEATH; CLINICAL FEATURE; CREATININE BLOOD LEVEL; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTION; DISEASE COURSE; DISEASE SEVERITY; ENTERITIS; FEVER; HEALTH PROGRAM; HEALTH SURVEY; HUMAN; IMMUNOASSAY; INCIDENCE; INFECTION RISK; MULTIPLE MYELOMA; NAUSEA; NEUTROPENIA; NONHODGKIN LYMPHOMA; OUTCOMES RESEARCH; POPULATION RESEARCH; PRIMARY INFECTION; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RISK FACTOR; SEROLOGY; SYMPTOM; THROMBOCYTOPENIA; VIRUS REACTIVATION; WHOLE BODY RADIATION;

ANTIVIRAL AGENTS; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTIONS; HUMANS; IMMUNOCOMPROMISED HOST; INCIDENCE; LYMPHOMA, NON-HODGKIN; MULTIPLE MYELOMA; PHOSPHOPROTEINS; POPULATION SURVEILLANCE; PROGNOSIS; RISK FACTORS; STEM CELL TRANSPLANTATION; TRANSPLANTATION, AUTOLOGOUS; VIRAL MATRIX PROTEINS; VIREMIA;

EID: 29544445642     PISSN: 13982273     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1399-3062.2005.000111.x     Document Type: Article

References (14)

1. BOECKH M, STEVENS-AYERS T, BOWDEN RA. Cytomegalovirus pp65 antigenemia after autologous marrow and peripheral blood stem cell transplantation. J Infect Dis 1996: 174: 907-912.
2. LEUNG AN, GOSSELIN MV, NAPPER CH, et al. Pulmonary infections after bone marrow transplantation: clinical and radiographic findings. Radiology 1999: 210: 699-710.
3. LJUNGMAN P, BIRON P, BOSI A, et al. Cytomegalovirus interstitial pneumonia in autologous bone marrow transplant recipients. Infectious Disease Working Party of the European Group for Bone Marrow transplantation. Bone Marrow Transplant 1994: 13: 209-212.
4. KONOPLEV S, CHAMPLIN RE, GIRALT S, et al. Cytomegalovirus pneumonia in adult autologous blood and marrow transplant recipients. Bone Marrow Transplant 2001: 27: 877-881.
5. CASTAGNOLA E, DALLORSO S, RABAGLIATI M. Survival after cytomegalovirus pneumonia in two children receiving autologous peripheral blood progenitor cell transplantation (PBPCT). Bone Marrow Transplant 1998: 21: 529-531.
6. VAN KRAAIJ MG, DEKKER AW, VERDONCK LF. Infectious gastro-enteritis: an uncommon cause of diarrhoea in adult allogeneic and autologous stem cell transplant recipients. Bone Marrow Transplant 2000: 26: 299-303.
7. BILGRAMI S, ASLANZADEH J, FEINGOLD JM, et al. Cytomegalovirus viremia, viruria and disease after autologous peripheral blood stem cell transplantation: no need for surveillance. Bone Marrow Transplant 1999: 24: 69-73.
8. HOLMBERG LA, BOECKH M, HOOPER H, et al. Increased incidence of cytomegalovirus disease after CD-34 selected peripheral blood stem cell transplantation. Blood 1999: 94: 4029-4035.
9. ALESSANDRINO EP, VARETTONI M, COLOMBO AA, CALDERA D, BERNASCONI P, MALCOVATI L. High incidence of symptomatic cytomegalovirus infection in multiple myeloma patients undergoing autologous peripheral blood stem cell transplantation. Blood 2000: 95: 4016-4017.
10. SCHILLER GJ, VESCIO R, BERENSON J. Cytomegalovirus infection following transplantation of autologous CD-34 selected progenitor cells. Blood 2000: 96: 1194.
11. BEGGS KS, INGS SJ, KOTTARIDIS PD, et al. Cytomegalovirus infection and disease after autologous CD34 selected peripheral blood stem cell transplantation for multiple myeloma: no evidence of increased incidence based on polymerase chain reaction monitoring. Blood 2000: 96: 369-370.
12. JIWA NM, VAN DE RIJKE FM, MULDER A, et al. An improved immunocytochemical method for the detection of human cytomegalovirus antigen in peripheral leukocytes. Histochemistry 1989: 91: 345-349.
13. GERNA G, REVELLO MG, PERCIVALLE E, MORINI F. Comparison of different immunostaining techniques and monoclonal antibodies to the lower matrix phosphoprotein (pp65) for optimal quantitation of human cytomegalovirus antigenemia. J Clin Microbiol 1992: 30: 1232-1237.
14. FASSAS A, BOLANOS-MEADE J, BUDDHARAJU LN, et al. Cytomegalovirus infection and non-neutropenic fever after autologous stem cell transplantation: high rates of reactivation in patients with multiple myeloma and lymphoma. Br J Haematol 2001: 112: 237-241.