Design and synthesis of a Tat-related gene transporter: A tool for carrying the adenovirus vector into cells

Bioorganic and Medicinal Chemistry Letters

Volumn 16, Issue 3, 2006, Pages 743-745

  Kida, Shinya ^a   Maeda, Mitsuko ^a   Hojo, Keiko ^a   Eto, Yusuke ^b   Gao, Jian Qing ^b   Kurachi, Shinnosuke ^b   Mizuguchi, Hiroyuki ^b,c   Hayakawa, Takao ^d   Mayumi, Tadanori ^a   Nakagawa, Shinsaku ^b   Kawasaki, Koichi ^a  

^a KOBE GAKUIN UNIVERSITY   (Japan)

^b OSAKA UNIVERSITY   (Japan)

^c NATIONAL INSTITUTE OF BIOMEDICAL INNOVATION   (Japan)

^d PHARMACEUTICALS AND MEDICAL DEVICES AGENCY   (Japan)

Author keywords

Adenovirus vector; Peptide synthesis; Tat; Tat peptide

Indexed keywords

6 MALEIMIDOHEXANOIC ACID N HYDROXYSUCCINIMIDE ESTER; ACETYLGLYCYLARGINYLARGINYLARGINYLARGINYLARGINYLGLUTAMINYLARGINYLARGINYL ARGINYLPROLYLPROLYLGLUTAMINYLGLYCYLCYSTEINAMIDE; ADENOVIRUS VECTOR; CARRIER PROTEIN; LUCIFERASE; PEPTIDE; REAGENT; TRANSACTIVATOR PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL BASED GENE THERAPY; CROSS LINKING; DRUG CONJUGATION; DRUG DELIVERY SYSTEM; DRUG DESIGN; DRUG SYNTHESIS; DRUG TRANSPORT; ENZYME ACTIVITY; GENE CONSTRUCT; GENE TRANSFER; GENETIC TRANSDUCTION; MOUSE; NONHUMAN; SOLID PHASE SYNTHESIS; VIRAL GENE DELIVERY SYSTEM; WILD TYPE;

ADENOVIRIDAE; AMINO ACID SEQUENCE; ANIMALS; BIOLOGICAL TRANSPORT; CELL LINE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CROSS-LINKING REAGENTS; DRUG DESIGN; GENE PRODUCTS, TAT; GENETIC VECTORS; LUCIFERASES; MICE; MOLECULAR SEQUENCE DATA; OLIGOPEPTIDES; SUCCINIMIDES; TRANSDUCTION, GENETIC;

ADENOVIRIDAE; ANIMALIA;

EID: 29544435749     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.08.116     Document Type: Article

References (12)

1. R.G. Crystal Science 270 1995 404
2. J.M. Wilson N. Engl. J. Med. 334 1996 1185
3. M. Maeda, S. Kida, K. Hojo, Y. Eto, J.-Q. Gao, S. Kurachi, F. Sekiguchi, H. Mizuguchi, T. Hayakawa, T. Mayumi, S. Nakagawa, and K. Kawasaki Bioorg. Med. Chem. Lett. 15 2005 621
4. S. Fawell, J. Seery, Y. Daikh, C. Moore, L.L. Chen, B. Pepinsky, and J. Barsoum Proc. Natl. Acad. Sci. U.S.A. 91 1994 664
5. E. Vives, P. Brodin, and B. Lebleu J. Biol. Chem. 272 1997 16010
6. S. Futaki, T. Suzuki, W. Ohashi, T. Yagami, S. Tanaka, K. Ueda, and Y. Sugiura J. Biol. Chem. 276 2001 5836
7. S. Hashida, M. Imagawa, S. Inoue, K.H. Ruan, and E. Ishikawa J. Appl. Biochem. 6 1984 56
8. C. Fargeas, M. Hommel, R. Maingon, C. Dourado, M. Monsigny, and R. Mayer J. Clin. Microbiol. 34 1996 241
9. H. Rink Tetrahedron Lett. 28 1987 3787
10. R. Knorr, A. Trzecial, W. Bannwarth, and D. Gillessen Tetrahedron Lett. 30 1989 1927
11. 18S 1975.1).
12. N. Okada, Y. Tsukada, S. Nakagawa, H. Mizuguchi, K. Mori, T. Saito, T. Fujita, A. Yamamoto, T. Hayakawa, and T. Mayumi Biochem. Biophys. Res. Commun. 282 2001 173