메뉴 건너뛰기




Volumn 25, Issue 11, 2005, Pages 661-665

Impairment of membrane markers on peripheral blood mononuclear cells and imbalance of cytokine secretion in the pathogenesis of multiple sclerosis active phases

Author keywords

[No Author keywords available]

Indexed keywords

CD40 ANTIGEN; CD40 LIGAND; CELL MEMBRANE MARKER; CYTOKINE; FAS ANTIGEN; FAS LIGAND; MYELIN; TUMOR NECROSIS FACTOR RECEPTOR 1; TUMOR NECROSIS FACTOR RECEPTOR 2; FASLG PROTEIN, HUMAN; MEMBRANE PROTEIN; TUMOR NECROSIS FACTOR;

EID: 29444456900     PISSN: 10799907     EISSN: None     Source Type: Journal    
DOI: 10.1089/jir.2005.25.661     Document Type: Article
Times cited : (4)

References (55)
  • 2
    • 0028317040 scopus 로고
    • Natural history of multiple sclerosis
    • Weinshenker BG. Natural history of multiple sclerosis. Ann. Neurol. 1994;36(Suppl.):S6-S11.
    • (1994) Ann. Neurol. , vol.36 , Issue.SUPPL.
    • Weinshenker, B.G.1
  • 3
    • 0031739621 scopus 로고    scopus 로고
    • Etiology and pathogenesis of multiple sclerosis
    • Sorensen TL, Ransohoff RM. Etiology and pathogenesis of multiple sclerosis. Semin. Neurol. 1998;18:287-294.
    • (1998) Semin. Neurol. , vol.18 , pp. 287-294
    • Sorensen, T.L.1    Ransohoff, R.M.2
  • 5
    • 0034982596 scopus 로고    scopus 로고
    • Immunological update on multiple sclerosis
    • Hohlfeld R, Wekerle H. Immunological update on multiple sclerosis. Curr. Opin. Neurol. 2001;14:299-304.
    • (2001) Curr. Opin. Neurol. , vol.14 , pp. 299-304
    • Hohlfeld, R.1    Wekerle, H.2
  • 6
    • 0035426664 scopus 로고    scopus 로고
    • Multiple sclerosis: More than inflammation and demyelination
    • Riekmann P, Smith KJ. Multiple sclerosis: more than inflammation and demyelination. Trends Neurosci. 2001;24:435-437.
    • (2001) Trends Neurosci. , vol.24 , pp. 435-437
    • Riekmann, P.1    Smith, K.J.2
  • 7
    • 0024999613 scopus 로고
    • Upregulation and coexpression of adhesion molecules correlate with relapsing autoimmune demyelination in the central nervous system
    • Cannella B, Cross AH, Raine CS. Upregulation and coexpression of adhesion molecules correlate with relapsing autoimmune demyelination in the central nervous system. J. Exp. Med. 1990;172: 1521-1524.
    • (1990) J. Exp. Med. , vol.172 , pp. 1521-1524
    • Cannella, B.1    Cross, A.H.2    Raine, C.S.3
  • 9
    • 0026556063 scopus 로고
    • Frequency of T cells specific for myelin basic protein and myelin proteolipid protein in blood and cerebrospinal fluid in multiple sclerosis
    • Chou Y, Bourdette D, Offner H, Witham R, Wang R, Hasheim G. Frequency of T cells specific for myelin basic protein and myelin proteolipid protein in blood and cerebrospinal fluid in multiple sclerosis. J. Neuroimmunol. 1992;38:105-114.
    • (1992) J. Neuroimmunol. , vol.38 , pp. 105-114
    • Chou, Y.1    Bourdette, D.2    Offner, H.3    Witham, R.4    Wang, R.5    Hasheim, G.6
  • 10
    • 0028227138 scopus 로고
    • The D.E. McFarlin Memorial Lecture: The immunology of multiple sclerosis
    • Raine CS. The D.E. McFarlin Memorial Lecture: the immunology of multiple sclerosis. Ann. Neurol. 1994;36:S61-S72.
    • (1994) Ann. Neurol. , vol.36
    • Raine, C.S.1
  • 12
    • 0035554898 scopus 로고    scopus 로고
    • Multiple sclerosis: A two stage disease
    • Steinman L. Multiple sclerosis: a two stage disease. Nat. Immunol. 2001;2:762-764.
    • (2001) Nat. Immunol. , vol.2 , pp. 762-764
    • Steinman, L.1
  • 13
    • 0029022855 scopus 로고
    • Macrophages in T cell line-mediated, demyelinating, and chronic relapsing experimental autoimmune encephalomyelitis in Lewis rats
    • Huitinga I, Ruuls SR, Jung S, Van Rooijen N, Hartung HP, Dijkstra CD. Macrophages in T cell line-mediated, demyelinating, and chronic relapsing experimental autoimmune encephalomyelitis in Lewis rats. Clin. Exp. Immunol. 1995;100:344-351.
    • (1995) Clin. Exp. Immunol. , vol.100 , pp. 344-351
    • Huitinga, I.1    Ruuls, S.R.2    Jung, S.3    Van Rooijen, N.4    Hartung, H.P.5    Dijkstra, C.D.6
  • 14
    • 0033926601 scopus 로고    scopus 로고
    • Apoptosis in multiple sclerosis
    • Zipp F. Apoptosis in multiple sclerosis. Cell Tissue Res. 2000;301:163-171.
    • (2000) Cell Tissue Res. , vol.301 , pp. 163-171
    • Zipp, F.1
  • 15
    • 29444435581 scopus 로고
    • Increased production of IFN-γ and TNF precedes clinical manifestation in multiple sclerosis: Do cytokines trigger off exacerbation?
    • Beck J, Rondot P, Catinot L, Falcoff E, Kirchner A, Wilizerbin J. Increased production of IFN-γ and TNF precedes clinical manifestation in multiple sclerosis: do cytokines trigger off exacerbation? Acta Neurol. Scand. 1988;78:1985-1996.
    • (1988) Acta Neurol. Scand. , vol.78 , pp. 1985-1996
    • Beck, J.1    Rondot, P.2    Catinot, L.3    Falcoff, E.4    Kirchner, A.5    Wilizerbin, J.6
  • 16
    • 0028228282 scopus 로고
    • Increased expression of high affinity IL-2 receptors and beta-adrenoceptors on peripheral blood cells is associated with clinical and MRI activity in multiple sclerosis
    • Zoukos Y, Kidd D, Woodroofe MN, Kendal BE, Thompson AJ, Cuzner ML. Increased expression of high affinity IL-2 receptors and beta-adrenoceptors on peripheral blood cells is associated with clinical and MRI activity in multiple sclerosis. Brain 1994;117:307-315.
    • (1994) Brain , vol.117 , pp. 307-315
    • Zoukos, Y.1    Kidd, D.2    Woodroofe, M.N.3    Kendal, B.E.4    Thompson, A.J.5    Cuzner, M.L.6
  • 19
    • 0035936797 scopus 로고    scopus 로고
    • The TNF and TNF receptor superfamilies: Integrating mammalian biology
    • Locksley RM, Killeen N, Lenardo MI. The TNF and TNF receptor superfamilies: integrating mammalian biology. Cell 2001;104:487-500.
    • (2001) Cell , vol.104 , pp. 487-500
    • Locksley, R.M.1    Killeen, N.2    Lenardo, M.I.3
  • 21
    • 0034641898 scopus 로고    scopus 로고
    • CD95's deadly mission in the immune system
    • Krammer PH. CD95's deadly mission in the immune system. Nature 2000;407:789-795.
    • (2000) Nature , vol.407 , pp. 789-795
    • Krammer, P.H.1
  • 22
    • 0034574306 scopus 로고    scopus 로고
    • The multifacted role of Fas signaling in immune cell homeostasis and autoimmunity
    • Siegel RM, Chan FK, Chun HI, Lenardo MI. The multifacted role of Fas signaling in immune cell homeostasis and autoimmunity. Nat. Immunol. 2000;1:469-474.
    • (2000) Nat. Immunol. , vol.1 , pp. 469-474
    • Siegel, R.M.1    Chan, F.K.2    Chun, H.I.3    Lenardo, M.I.4
  • 23
    • 0029993331 scopus 로고    scopus 로고
    • Apoptosis and the maintenance of homeostasis in the immune system
    • Osborne BA. Apoptosis and the maintenance of homeostasis in the immune system. Curr. Opin. Immunol. 1996;8:245-254.
    • (1996) Curr. Opin. Immunol. , vol.8 , pp. 245-254
    • Osborne, B.A.1
  • 24
    • 0031066394 scopus 로고    scopus 로고
    • The molecular regulation of lymphocyte apoptosis
    • Lenardo MI. The molecular regulation of lymphocyte apoptosis. Semin. Immunol. 1997;9:1-5.
    • (1997) Semin. Immunol. , vol.9 , pp. 1-5
    • Lenardo, M.I.1
  • 26
    • 0021035886 scopus 로고
    • Rating neurologic impairment in multiple sclerosis: An expanded disability status scale (EDSS)
    • Kurtzke JF. Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS). Neurology 1983;33: 1444-1452.
    • (1983) Neurology , vol.33 , pp. 1444-1452
    • Kurtzke, J.F.1
  • 29
    • 0029073133 scopus 로고
    • CD40 on human endothelial cells: Inducibility by cytokines and functional regulation of adhesion molecule expression
    • Karmann K, Hughes, C, Schechner J, Fanslow WC, Pober JS. CD40 on human endothelial cells: inducibility by cytokines and functional regulation of adhesion molecule expression. Proc. Natl. Acad. Sci. USA 1995;92:4342-4346.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 4342-4346
    • Karmann, K.1    Hughes, C.2    Schechner, J.3    Fanslow, W.C.4    Pober, J.S.5
  • 31
    • 0031944607 scopus 로고    scopus 로고
    • CD40 and CD154 in cell-mediated immunity
    • Grewal IS, Flavell RA. CD40 and CD154 in cell-mediated immunity. Annu. Rev. Immunol. 1998;16:111-135.
    • (1998) Annu. Rev. Immunol. , vol.16 , pp. 111-135
    • Grewal, I.S.1    Flavell, R.A.2
  • 33
    • 0035824895 scopus 로고    scopus 로고
    • CD40 signaling and plaque instability
    • Schonbeck U, Libby P. CD40 signaling and plaque instability. Circ. Res. 2001;89:1092-1103.
    • (2001) Circ. Res. , vol.89 , pp. 1092-1103
    • Schonbeck, U.1    Libby, P.2
  • 35
    • 0031933496 scopus 로고    scopus 로고
    • The cytokine storm in multiple sclerosis
    • Link H. The cytokine storm in multiple sclerosis. Mult. Scler. 1998;4:12-15.
    • (1998) Mult. Scler. , vol.4 , pp. 12-15
    • Link, H.1
  • 36
    • 0032744256 scopus 로고    scopus 로고
    • Cytokine analysis in multiple sclerosis by competitive RT-PCR: A decreased expression of IL-10 and an increased expression of TNF-alpha in chronic progression
    • Huang WX, Huang P, Link H, Hillert J. Cytokine analysis in multiple sclerosis by competitive RT-PCR: a decreased expression of IL-10 and an increased expression of TNF-alpha in chronic progression. Mult. Scler. 1999;5:342-348.
    • (1999) Mult. Scler. , vol.5 , pp. 342-348
    • Huang, W.X.1    Huang, P.2    Link, H.3    Hillert, J.4
  • 37
    • 0034071168 scopus 로고    scopus 로고
    • Elevated CD40 ligand expressing blood T-cell levels in multiple sclerosis are reversed by interferon-beta treatment
    • Teleshova N, Bao W, Kivisäkk P, Özenci V, Mustafa M, Link H. Elevated CD40 ligand expressing blood T-cell levels in multiple sclerosis are reversed by interferon-beta treatment. Scand. J. Immunol. 2000;51:312-320.
    • (2000) Scand. J. Immunol. , vol.51 , pp. 312-320
    • Teleshova, N.1    Bao, W.2    Kivisäkk, P.3    Özenci, V.4    Mustafa, M.5    Link, H.6
  • 38
    • 0034000554 scopus 로고    scopus 로고
    • Systemic upregulation of CD40 and CD40 ligand mRNA expression in multiple sclerosis
    • Huang WX, Huang P, Hillert J. Systemic upregulation of CD40 and CD40 ligand mRNA expression in multiple sclerosis. Mult. Scler. 2000;6:61-65.
    • (2000) Mult. Scler. , vol.6 , pp. 61-65
    • Huang, W.X.1    Huang, P.2    Hillert, J.3
  • 39
    • 0025780152 scopus 로고
    • MHC class II-associated variation in the production of tumor necrosis factor in mice and in humans: Relevance to the pathogenesis of autoimmune diseases
    • Jacob CO, Lewis GD, McDevitt HO. MHC class II-associated variation in the production of tumor necrosis factor in mice and in humans: relevance to the pathogenesis of autoimmune diseases. Immunol. Rev. 1991;10:156-168.
    • (1991) Immunol. Rev. , vol.10 , pp. 156-168
    • Jacob, C.O.1    Lewis, G.D.2    McDevitt, H.O.3
  • 40
    • 0033515463 scopus 로고    scopus 로고
    • Tumor necrosis factor-α mediates both apoptotic cell death and cell proliferation in a human hematopoietic cell line dependent on mitotic activity and receptor subtype expression
    • Baxter TG, Kuo RC, Orla JJ, Vandenabeele P, MacEwan DJ. Tumor necrosis factor-α mediates both apoptotic cell death and cell proliferation in a human hematopoietic cell line dependent on mitotic activity and receptor subtype expression. J. Biol. Chem. 1999;274:9539-9547.
    • (1999) J. Biol. Chem. , vol.274 , pp. 9539-9547
    • Baxter, T.G.1    Kuo, R.C.2    Orla, J.J.3    Vandenabeele, P.4    MacEwan, D.J.5
  • 42
    • 0032562704 scopus 로고    scopus 로고
    • Early activation of c-Jun N-terminal kinase and p-38 kinase regulate cell survival in response to tumor necrosis factor-α
    • Roulston A, Reinhard C, Amiri P, Williams LT. Early activation of c-Jun N-terminal kinase and p-38 kinase regulate cell survival in response to tumor necrosis factor-α. J. Biol. Chem. 1998;273: 10232-10238.
    • (1998) J. Biol. Chem. , vol.273 , pp. 10232-10238
    • Roulston, A.1    Reinhard, C.2    Amiri, P.3    Williams, L.T.4
  • 43
    • 0028927607 scopus 로고
    • The Fas death factor
    • Nagata S, Goldstein P. The Fas death factor. Science 1995;267:1449-1456.
    • (1995) Science , vol.267 , pp. 1449-1456
    • Nagata, S.1    Goldstein, P.2
  • 44
    • 0026497684 scopus 로고
    • Differential expression of apoptosis-related Fas antigen on lymphocyte subpopulations in human peripheral blood
    • Miyawaki T, Uehara T, Nibu R, Tsuij T, Yachie A, Yonehara S, Taniguchi N. Differential expression of apoptosis-related Fas antigen on lymphocyte subpopulations in human peripheral blood. J. Immunol. 1992;149:3753-3758.
    • (1992) J. Immunol. , vol.149 , pp. 3753-3758
    • Miyawaki, T.1    Uehara, T.2    Nibu, R.3    Tsuij, T.4    Yachie, A.5    Yonehara, S.6    Taniguchi, N.7
  • 46
    • 0030738366 scopus 로고    scopus 로고
    • Multiple sclerosis oligodendrocytes display cell death-related molecules in situ but do not undergo apoptosis
    • Bonetti B, Raine CS. Multiple sclerosis oligodendrocytes display cell death-related molecules in situ but do not undergo apoptosis. Ann. Neurol. 1997;42:74-84.
    • (1997) Ann. Neurol. , vol.42 , pp. 74-84
    • Bonetti, B.1    Raine, C.S.2
  • 47
    • 0033525162 scopus 로고    scopus 로고
    • Impaired apoptosis in mitogen-stimulated lymphocytes of patients with multiple sclerosis
    • Macchi B, Matteucci C, Nocentini U, Caltagirone C, Mastino A. Impaired apoptosis in mitogen-stimulated lymphocytes of patients with multiple sclerosis. Neuroreport 1999;10:399-402.
    • (1999) Neuroreport , vol.10 , pp. 399-402
    • Macchi, B.1    Matteucci, C.2    Nocentini, U.3    Caltagirone, C.4    Mastino, A.5
  • 48
    • 0034633711 scopus 로고    scopus 로고
    • Fas(t) track to apoptosis in MS: TNF receptors may suppress or potentiate CNS demyelinating
    • Segal BM, Cross AH. Fas(t) track to apoptosis in MS: TNF receptors may suppress or potentiate CNS demyelinating. Neurology 2000;55:906-907.
    • (2000) Neurology , vol.55 , pp. 906-907
    • Segal, B.M.1    Cross, A.H.2
  • 49
    • 0030561022 scopus 로고    scopus 로고
    • Increased Fas antigen on T cells in multiple sclerosis
    • Ichikawa H, Ota K, Iwata M. Increased Fas antigen on T cells in multiple sclerosis. J. Neuroimmunol. 1996;71:125-129.
    • (1996) J. Neuroimmunol. , vol.71 , pp. 125-129
    • Ichikawa, H.1    Ota, K.2    Iwata, M.3
  • 50
    • 0031891009 scopus 로고    scopus 로고
    • Cytokine production and surface marker expression in acute and stable multiple sclerosis: Altered IL-12 production and augmented signaling lymphocytic activation molecule (SLAM)-expressing lymphocytes in acute multiple sclerosis
    • Ferrante P, Fusi ML, Saresella M, Caputo D, Biasin M, Trabattoni D, Salvaggio A, Clerici E, de Vries JE, Aversa G, Cazzullo CL, Clerici M. Cytokine production and surface marker expression in acute and stable multiple sclerosis: altered IL-12 production and augmented signaling lymphocytic activation molecule (SLAM)-expressing lymphocytes in acute multiple sclerosis. J. Immunol. 1998;160:1514-1521.
    • (1998) J. Immunol. , vol.160 , pp. 1514-1521
    • Ferrante, P.1    Fusi, M.L.2    Saresella, M.3    Caputo, D.4    Biasin, M.5    Trabattoni, D.6    Salvaggio, A.7    Clerici, E.8    De Vries, J.E.9    Aversa, G.10    Cazzullo, C.L.11    Clerici, M.12
  • 51
    • 0034633769 scopus 로고    scopus 로고
    • Apoptosis mediators FasL and TRAIL are upregulated in peripheral blood mononuclear cells in MS
    • Huang WX, Huang, MP, Gomes MA, Hillert J. Apoptosis mediators FasL and TRAIL are upregulated in peripheral blood mononuclear cells in MS. Neurology 2000;55:928-934.
    • (2000) Neurology , vol.55 , pp. 928-934
    • Huang, W.X.1    Huang, M.P.2    Gomes, M.A.3    Hillert, J.4
  • 52
    • 0037308835 scopus 로고    scopus 로고
    • Upregulation of the apoptosis regulators cFLIP, CD95 and CD95 ligand in peripheral blood mononuclear cells in relapsing-remitting multiple sclerosis
    • Gomes AC, Jonsson G, Mjornheim S, Olsson T, Hillert J, Grandien A. Upregulation of the apoptosis regulators cFLIP, CD95 and CD95 ligand in peripheral blood mononuclear cells in relapsing-remitting multiple sclerosis. J. Neuroimmunol. 2003;135:126-134.
    • (2003) J. Neuroimmunol. , vol.135 , pp. 126-134
    • Gomes, A.C.1    Jonsson, G.2    Mjornheim, S.3    Olsson, T.4    Hillert, J.5    Grandien, A.6
  • 53
    • 0037960322 scopus 로고    scopus 로고
    • The development of clinical activity in relapsing-remitting MS is associated with a decrease of FasL mRNA and an increase of Fas mRNA in peripheral blood
    • Lopatinskaya L, van Boxel-Dezaire AH, Barkhof F, Polman CH, Lucas CJ, Nagelkerken L. The development of clinical activity in relapsing-remitting MS is associated with a decrease of FasL mRNA and an increase of Fas mRNA in peripheral blood. J. Neuroimmunol. 2003;138:123-131.
    • (2003) J. Neuroimmunol. , vol.138 , pp. 123-131
    • Lopatinskaya, L.1    Van Boxel-Dezaire, A.H.2    Barkhof, F.3    Polman, C.H.4    Lucas, C.J.5    Nagelkerken, L.6
  • 54
    • 2642577281 scopus 로고    scopus 로고
    • CD95/Fas expression on peripheral blood T lymphocytes in patients with multiple sclerosis: Effect of high-dose methylprednisolone therapy
    • Petelin Z, Brinar V, Petravic D, Zurak N, Dubravcic K, Batinic D. CD95/Fas expression on peripheral blood T lymphocytes in patients with multiple sclerosis: effect of high-dose methylprednisolone therapy. Clin. Neurol. Neurosurg. 2004;106:259-262.
    • (2004) Clin. Neurol. Neurosurg. , vol.106 , pp. 259-262
    • Petelin, Z.1    Brinar, V.2    Petravic, D.3    Zurak, N.4    Dubravcic, K.5    Batinic, D.6
  • 55
    • 0032934534 scopus 로고    scopus 로고
    • Impairment of TNF-receptor-I signaling but not Fas signaling diminished T cell apoptosis in myelin oligodendrocyte glycoprotein peptide-induced chronic demyelinating autoimmune encephalomyelitis in mice
    • Bachmann R, Eugster HP, Frei K, Fontana A, Lassmann H. Impairment of TNF-receptor-I signaling but not Fas signaling diminished T cell apoptosis in myelin oligodendrocyte glycoprotein peptide-induced chronic demyelinating autoimmune encephalomyelitis in mice. Am. J. Pathol. 1999;154:1417-1422.
    • (1999) Am. J. Pathol. , vol.154 , pp. 1417-1422
    • Bachmann, R.1    Eugster, H.P.2    Frei, K.3    Fontana, A.4    Lassmann, H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.