Association between the polymorphism of β-fibrinogen gene -455G/A and ischemic stroke

Chinese Journal of Medical Genetics

Volumn 21, Issue 3, 2004, Pages 274-276

  Dong, Qing Lin ^a   Zhang, Chen ^b  

^a PEOPLE S HOSPITAL OF RIZHAO   (China)

^b QINGDAO UNIVERSITY   (China)

Author keywords

Fibrinogen; Genetic polymorphism; Ischemic stroke

Indexed keywords

FIBRINOGEN; FIBRINOGEN B BETA CHAIN; UNCLASSIFIED DRUG;

ADULT; AGED; ALLELE; ARTICLE; CEREBROVASCULAR ACCIDENT; CONTROLLED STUDY; DNA POLYMORPHISM; FEMALE; FIBRINOGEN BLOOD LEVEL; GENE FREQUENCY; GENETIC ASSOCIATION; HUMAN; HYPERTENSION; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; PROMOTER REGION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM;

EID: 2942741283     PISSN: 10039406     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (13)

1. Grant PJ. Polymorphisms of coagulation/fibrin olysis genes: gene environment interactions and vascular risk. Prostaglandins Leukot Essent Fatty Acids, 1997, 57: 473-477.
2. Wilhelmsen L, Svardsudd K, Korsan-Bengtsen K, et al. Fibrinogen as a risk factor for stroke and myocardial infarction. N Engl J Med, 1984, 311: 501-505.
3. Ernst E, Koenig W. Fibrinogen and cardiovascular risk. Vasc Med, 1997, 2: 115-125.
4. Gardemann A, Schwartz O, Haberbosch W, et al. Positive association of the beta fibrinogen H1/H2 gene variation to basal fibrinogen levels and to the increase in fibrinogen concentration during acute phase reaction but not to coronary artery disease and myocardial infarction. Thromb Haemost, 1997, 77: 1120-1126.
5. Humphries SE, Cook M, Dubowitz M, et al. Role of genetic variation at the fibrinogen locus in determination of plasma fibrinogen concentrations. Lancet, 1987, 1: 1452-1455.
6. Nishiuma S, Kario K, Yakushijin K, et al. Genetic variation in the promoter region of the β-fibrinogen gene is associated with ischemic stroke in a Japanese population. Blood Coagul Fibrinolysis, 1998, 9: 373-379.
7. Krobot K, Hense HW, Cremer P, et al. Determinants of plasma fibrinogen: relation to body weight, waist-to-hip ratio, smoking, alcohol, age and sex. Results from the second MONICA Augsburg Survey 1989-1990. Arterioscler Thromb, 1992, 12: 780-788.
8. Sandset PM, Andersson TR. Coagulation inhibitor levels in pneumonia and stroke: changes due to consumption and acute phase reaction. J Intern Med, 1989, 225: 311-316.
9. Thomas AE, Green FR, Humphries SE. Association of genetic variation at the beta-fibrinogen gene locus and plasma fibrinogen levels; interaction between allele frequency of the G/A - 455 polymorphism, age and smoking. Clin Genet, 1996, 50: 184-190.
10. Green F, Hamsten A, Blomback M, et al. The role of beta-fibrinogen genotype in determining plasma fibrinogen levels in young survivors of myocardial infarction and healthy controls from Sweden. Thromb Haemost, 1993, 70: 915-920.
11. Iso H, Folsom AR, Winkelmann JC, et al. Polymorphisms of the beta fibrinogen gene and plasma fibrinogen concentration in Caucasian and Japanese population samples. Thromb Haemost, 1995, 73: 106-111.
12. Verschuur M, Bekkers M, Van Erck MG, et al. Influence of plasma triglyceride and plasma cholesterol levels on the clearance rate of fibrinogen. Ann N Y Acad Sci, 2001, 936: 639-642.
13. Zhang Z, Fuller GM. Interleukin I beta inhibits interleukin 6-mediated rat gamma fibrinogen gene expression. Blood, 2000, 96: 3466-3472.