Cloning and characterization of the human β2-glycoprotein I (β2-GPI) gene promoter: Roles of the atypical TATA box and hepatic nuclear factor-1α in regulating β2-GPI promoter activity

Biochemical Journal

Volumn 380, Issue 2, 2004, Pages 455-463

  Wang, Hsueh Hsiao ^a   Chiang, An Na ^a  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

Author keywords

2 glycoprotein I; Gene regulation; Hepatic nuclear factor 1 (HNF 1 ); Hepg2 cells; Huh7 cells

Indexed keywords

BIOCHEMISTRY; BIOLOGICAL ORGANS; BIOSYNTHESIS; DISEASES; GENES; HUMAN ENGINEERING; METABOLISM; PROTEINS;

GEL MOBILITY SHIFT ASSAYS; GLYCOPROTEINS; LIVERS;

CLONING;

BETA2 GLYCOPROTEIN 1; CIS ACTING ELEMENT; NUCLEAR FACTOR I;

ARTICLE; CONTROLLED STUDY; DNA FLANKING REGION; EXPRESSION VECTOR; FEMALE; GEL MOBILITY SHIFT ASSAY; GENE ACTIVITY; GENE CONTROL; GENE DELETION; GENE EXPRESSION; GENE SEQUENCE; HUMAN; HUMAN CELL; MOLECULAR CLONING; MOLECULAR TYPING; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN PROTEIN INTERACTION; SITE DIRECTED MUTAGENESIS; TATA BOX;

5' FLANKING REGION; BASE SEQUENCE; BETA 2-GLYCOPROTEIN I; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CLONING, MOLECULAR; DNA, NEOPLASM; DNA-BINDING PROTEINS; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ENHANCER ELEMENTS (GENETICS); GLYCOPROTEINS; HELA CELLS; HEPATOCYTE NUCLEAR FACTOR 1; HEPATOCYTE NUCLEAR FACTOR 1-ALPHA; HUMANS; LIVER NEOPLASMS; MOLECULAR SEQUENCE DATA; NUCLEAR PROTEINS; PROMOTER REGIONS (GENETICS); TATA BOX; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTORS; TRANSCRIPTION INITIATION SITE; TRANSFECTION;

VECTORS;

EID: 2942731373     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20031610     Document Type: Article

References (45)

1. 2-glycoprotein I. Proc. Natl. Acad. Sci. U.S.A. 81, 3640-3364
2. Klickstein, L. B., Wong, W. W., Smith, J. A., Weis, J. H., Wilson, J. G. and Fearon, D. T. (1987) Human C3b/C4b receptor (CR1) demonstration of long homologous repeating domains that are composed of the short consensus repeats characteristic of C3/C4 binding proteins. J. Exp. Med. 165, 1095-1112
3. 2-glycoptotein I: implications for phospholipid binding and the antiphospholipid syndrome. EMBO J. 18, 6228-6239
4. 2- glycoprotein I to human serum lipoproteins: distribution among density fractions. FEBS Lett. 102, 183-186
5. Kamboh, M. I. and Ferrell, R. E. (1991) Apolipoprotein H polymorphism and its role in lipid metabolism. Adv. Lipid Res. 1, 9-18
6. 2-glycoprotein I null mice. J. Biol. Chem. 276, 13817-13821
7. 2-glycoprotein I. Biochim. Biophys. Acta 884, 142-149
8. 2- glycoprotein I (apoH) inhibits the release reaction of human platelets during ADP-induced aggregation. Atherosclerosis 63, 109-114
9. 2- glycoprotein I antibody complexes. J. Biol. Chem. 276, 3060-3067
10. 2-glycoprotein I. J. Clin. Invest. 90, 1100-1104
11. 2-glycoprotein I in patients with primary anti-phospholipid syndrome. J. Rheumatol. 22, 1894-1898
12. 2-glycoprotein I and clinical manifestations in patients with systemic lupus erythematosus. Arth. Rheum. 39, 1465-1474
13. Hwang, K. K., Grossman, J. M., Visvanathan, S., Chukwuocha, R. U., Woods, Jr, V. L., Le, D. T., Hahn, B. H. and Chen, P. P. (2001) Identification of anti-thrombin antibodies in the antiphospholipid syndrome that interferes with the inactivation of thrombin by antithrombin. J. Immunol. 167, 7192-7198
14. 2-glycoprotein I in patients with the antiphospholipid syndrome. J. Immunol. 162, 6919-6925
15. 2-glycoprotein I and anticardiolipin antibodies in oxidatively modified low-density lipoprotein uptake by macrophages. Clin. Exp. Immunol. 107, 569-573
16. 2- glycoprotein I). Life Sci. 69, 707-719
17. 2-glycoprotein I to chromosome 17. Cytogenet. Cell Genet. 58, 2005
18. 2- glycoprotein I) to human chromosome 17q23-qter; determination of the major expression site. Cytogenet. Cell Genet. 60, 31-33
19. Sanghera, D. K., Kristensen, T., Hamman, R. F. and Kamboh, M. I. (1997) Molecular basis of the apolipoprotein H (β-glycoprotein I) protein polymorphism. Hum. Genet. 100, 57-62
20. 2- glycoprotein I) gene affects plasma apolipoprotein H concentrations. Hum. Genet. 105, 63-71
21. 2-glycoprotein I). Gene 108, 293-298
22. Sambrook, J., Fritsch, E. F. and Maniatis, E. F. (1989) Molecular Cloning: A Laboratory Manual, 2nd edn, Cold Spring Harbor Laboratory Press, Plainview, NY
23. You, L. R., Chen, C. M., Yeh, T. S., Tsai, T. Y., Mai, R. T., Lin, C. H. and Lee, Y. H. (1999) Hepatitis C virus core protein interacts with cellular putative RNA helicase. J. Virol. 73, 2841-2853
24. 2-glycoprotein I (apolipoprotein H) gene. Eur. J. Biochem. 259, 435-440
25. Quandt, K., Frech, K., Karas, H., Wingender, E. and Werner, T. (1995) MatInd and MatInspector: new fast and versatile tools for detection of consensus matches in nucleotide sequence data. Nucleic Acids Res. 23, 4878-4884
26. 2-glycoprotein I). Int. J. Clin. Lab. Res. 21, 256-263
27. 2-glycoprotein I cDNA. FEBS Lett. 289, 183-186
28. 2-glycoprotein I. Biochem. J. 277, 387-391
29. Reese, M. G. (2001) Application of a time-delay neural network to promoter annotation in the Drosophila melanogaster genome. Comput. Chem. 26, 51-56
30. Knudsen, S. (1999) Promoter 2.0: for the recognition of PoIII promoter sequences. Bioinformatics 15, 356-361
31. Mendel, D. B., Hansen, L. P., Graves, M. K., Conley, P. B. and Crabtree, G. R. (1991) HNF-1α and HNF-1β (vHNF-1) share dimerization and homeo domains, but not activation domains, and form heterodimers in vitro. Genes Dev. 5, 1042-1056
32. Song, Y. H., Ray, K., Liebhaber, S. A. and Cooke, N. E. (1998) Vitamin D-binding protein gene transcription is regulated by the relative abundance of hepatocyte nuclear factors 1α and 1β. J. Biol. Chem. 273, 28408-28418
33. 2-glycoprotein I. Eur. J. Biochem. 270, 230-238
34. Lewis, B. A., Kim, T., K. and Orkin, S. H. (2000) A downstream element in the human β-globin promoter: evidence of extended sequence-specific transcription factor IID contacts. Proc. Natl. Acad. Sci. U.S.A. 97, 7172-7177
35. Leach, K. M., Vieira, K. F., Kang, S. H., Aslanian, A., Teichmann, M., Roeder, R. G. and Bungert, J. (2003) Characterization of the human β-globin downstream promoter region. Nucleic Acids Res. 31, 1292-1301
36. Baumhueter, S., Courtois, G. and Crabtree, G. R. (1988) A variant nuclear protein in dedifferentiated hepatoma cells binds to the same functional sequences in the β-fibrinogen gene promoter as HNF-1. EMBO J. 7, 2485-2493
37. Cereghini, S., Raymondjean, M., Carranca, A. G., Herbomel, P. and Yaniv, M. (1987) Factors involved in control of tissue-specific expression of albumin gene. Cell (Cambridge, Mass.) 50, 627-638
38. Bois-Joyeux, B. and Danan, J. L. (1994) Members of the CAAT/enhancer-binding protein, hepatocyte nuclear factor-1 and nuclear factor-1 families can differentially modulate the activities of the rat α-fetoprotein promoter and enhancer. Biochem. J. 301, 49-55
39. Faust, D. M., Catherin, A. M., Barbaux, S., Belkadi, L., Imaizumi-Scherrer, T. and Weiss, M. C. (1996) The activity of the highly inducible mouse phenylalanine hydroxylase gene promoter is dependent upon a tissue-specific, hormone-inducible enhancer. Mol. Cell. Biol. 16, 3125-3137
40. Tronche, F. and Yaniv, M. (1992) HNF1, a homeoprotein member of the hepatic transcription regulatory network. Bioessays 14, 579-587
41. McGlynn, L. K., Mueller, C. R., Begbie, M., Notley, C. R. and Lillicrap, D. (1996) Role of the liver-enriched transcription factor hepatocyte nuclear factor 1 in transcriptional regulation of the factor VIII gene. Mol. Cell. Biol. 16, 1936-1945
42. Soutoglou, E., Papafotiou, G., Katrakili, N. and Talianidis, I. (2000) Transcriptional activation by hepatocyte nuclear factor-1 requires synergism between multiple coactivalor proteins. J. Biol. Chem. 275, 12515-12520
43. He, X., Futterer, J. and Hohn, T. (2002) Contribution of downstream promoter elements to transcriptional regulation of the rice tungro bacilliform virus promoter. Nucleic Acids Res. 30, 497-506
44. Knutson, A., Castano, E., Oelgeschlager, T., Roeder, R. G. and Westin, G. (2000) Downstream promoter sequences facilitate the formation of a specific transcription factor IID-promoter complex topology required for efficient transcription from the megalin/low density lipoprotein receptor-related protein 2 promoter. J. Biol. Chem. 275, 14190-14197
45. Wu, C. H., Madabusi, L., Nishioka, H., Emanuel, P., Sypes, M., Arkhipova, I. and Gilmour, D. S. (2001) Analysis of core promoter sequences located downstream from the TATA element in the hsp70 promoter from Drosophila melanogaster. Mol. Cell. Biol. 21, 1593-1602