Therapeutic angiogenesis by autologous transplantation of bone-marrow cells in a patient with progressive limb ischemia due to arteriosclerosis obliterans: A case report

Journal of Cardiology

Volumn 43, Issue 4, 2004, Pages 179-183

  Hasebe, Hideyuki ^a   Osada, Mitsuru ^a   Kodama, Yasushi ^a   Fujioka, Daisuke ^a   Sano, Keita ^a   Nakamura, Takamitsu ^a   Mitsumori, Tohru ^a   Nakamura, Kazuto ^a   Kitta, Yoshinobu ^a   Ichiki, Yoshihide ^a   Obata, Jyunei ^a   Kawabata, Kenichi ^a   Yanagi, Mitsuaki ^a   Sano, Sohichi ^a   Takano, Hajime ^a   Umetani, Ken ^a   Kugiyama, Kiyotaka ^a  

^a UNIVERSITY OF YAMANASHI   (Japan)

Author keywords

Angiogenesis; Arteriosclerosis; Transplantation (bone marrow cells)

Indexed keywords

AGED; ANGIOGENESIS; ANGIOGRAPHY; ARTICLE; AUTOLOGOUS BONE MARROW TRANSPLANTATION; CASE REPORT; CLINICAL FEATURE; DISEASE SEVERITY; FEMALE; FOLLOW UP; HUMAN; LEG PAIN; LIMB ISCHEMIA; MONONUCLEAR CELL; PERIPHERAL OCCLUSIVE ARTERY DISEASE; AUTOTRANSPLANTATION; BONE MARROW TRANSPLANTATION; DISEASE COURSE; ISCHEMIA; LEG; PHYSIOLOGY; TREATMENT OUTCOME; VASCULARIZATION;

AGED; ARTERIOSCLEROSIS OBLITERANS; BONE MARROW TRANSPLANTATION; DISEASE PROGRESSION; FEMALE; FOLLOW-UP STUDIES; HUMANS; ISCHEMIA; LOWER EXTREMITY; NEOVASCULARIZATION, PHYSIOLOGIC; TRANSPLANTATION, AUTOLOGOUS; TREATMENT OUTCOME;

EID: 2942729589     PISSN: 09145087     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (6)

1. Tateishi-Yuyama E, Matsubara H, Murohara T, Ikeda U, Shintani S, Masaki H, Amano K, Kishimoto Y, Yoshimoto K, Akashi H, Shimada K, Iwasaka T, Imaizumi T, Therapeutic Angiogenesis using Cell Transplantation (TACT) Study Investigators: Therapeutic angiogenesis for patients with limb ischaemia by autologous transplantation of bone-marrow cells: A pilot study and a randomised controlled trial. Lancet 2002; 360: 427-435
2. Shi Q, Rafii S, Wu MH, Wijelath ES, Yu C, Ishida A, Fujita Y, Kothari S, Mohle R, Sauvage LR, Moore MA, Storb RF, Hammond WP: Evidence for circulating bone marrow-derived endothelial cells. Blood 1998; 92: 362-367
3. Takeshita S, Zheng LP, Brogi E, Kearney M, Pu LQ, Bunting S, Ferrara N, Symes JF, Isner JM: Therapeutic angiogenesis: A single intraarterial bolus of vascular endothelial growth factor augments revascularization in a rabbit ischemic hind limb model. J Clin Invest 1994; 93: 662-670
4. Bender JG, Unverzagt KL, Walker DE, Lee W, Van Epps DE, Smith DH, Stewart CC, To LB: Identification and comparison of CD34-positive cells and their subpopulations from normal peripheral blood and bone marrow using multicolor flow cytometry. Blood 1991; 77: 2591-2596
5. Isner JM, Baumgartner I, Rauh G, Schainfeld R, Blair R, Manor O, Razv S, Symes JF: Treatment of thromboangiitis obliterans (Buerger's disease) by intramuscular gene transfer of vascular endothelial growth factor: Preliminary clinical results. J Vasc Surg 1998; 28: 964-973
6. Shyu KG, Chang H, Wang BW, Kuan P: Intramuscular vascular endothelial growth factor gene therapy in patients with chronic critical leg ischemia. Am J Med 2003; 114: 85-92