Influences of layering on theophylline pellet characteristics

Pharmaceutical Development and Technology

Volumn 9, Issue 2, 2004, Pages 163-170

  Sinchaipanid, Nuttanan ^a   Chitropas, Padungkwan ^b   Mitrevej, Ampol ^a  

^a MAHIDOL UNIVERSITY   (Thailand)

^b KHON KAEN UNIVERSITY   (Thailand)

Author keywords

Layering process; Pellet; Theophylline

Indexed keywords

CITRIC ACID TRIETHYL ESTER; EUDRAGIT; EUDRAGIT RS; HPC L; HYDROXYPROPYLCELLULOSE; HYDROXYPROPYLMETHYLCELLULOSE; MORFLEX; THEOPHYLLINE;

AQUEOUS SOLUTION; ARTICLE; DENSITY; DRUG PELLET; FILM COATING; PARTICLE SIZE; PELLET EXTRUSION; POROSITY; POWDER; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; SUSPENSION; THICKNESS; X RAY POWDER DIFFRACTION;

CELLULOSE; DRUG COMPOUNDING; EXCIPIENTS; METHYLCELLULOSE; PARTICLE SIZE; POWDERS; SURFACE PROPERTIES; SUSPENSIONS; TABLETS, ENTERIC-COATED; THEOPHYLLINE; TIME FACTORS; X-RAY DIFFRACTION;

EID: 2942715078     PISSN: 10837450     EISSN: None     Source Type: Journal    
DOI: 10.1081/PDT-120030246     Document Type: Article

References (16)

1. Mitrevej, A.; Sinchaipanid, N.; Natpoolwat, N.; Naratikornrit, N. Fabrication of multiunit controlled-release phenylpropanolamine hydrochloride tablets. Drug Dev. Ind. Pharm. 1998, 24 (8), 793-796.
2. Ghebre-Sellassie, I. Pellets: a general overview. In Pharmaceutical Pelletization Technology; Ghebre-Sellassie, I., Ed.; Marcel Dekker: New York, 1989; 1-14.
3. Bechgaard, H.; Nielsen, G.H. Controlled-release multiple-units and single-unit dose: a literature review. Drug Dev. Ind. Pharm. 1978, 4 (1), 53-67.
4. Appelgren, C. Recent advances in granulation technology and equipment. Drug Dev. Ind. Pharm. 1985, 11 (2&3), 725-741.
5. Poster, S.C. Controlled-release film coatings based on ethylcellulose. Drug Dev. Ind. Pharm. 1989, 15 (10), 1495-1521.
6. Iyer, U.; Hong, W.; Das, N.; Ghebre-Sellassie, I. Comparative evaluation of three organic solvent and dispersion-based ethylcellulose coating formation. Pharm. Technol. 1990, 14, 68-86. Sep.
7. Ghebre-Sellassie, I.; Gordon, R.H.; Nesbitt, R.U.; Fawzi, M.B. Evaluation of acrylic-based modified-release film coating. Int. J. Pharm. 1987, 37, 211-218.
8. Mullin, J.W. Sieving of pharmaceuticals. In Encyclopedia of Pharmaceutical Technology; Swarbrick, J., Boylan, J.C., Eds.; Marcel Dekker: New York, 1996; Vol. 14, 63-86.
9. Sienkiewicz, G.; Pereira, R.; Rudnic, E.M.; Lausier, J.M.; Rhodes, C.T. Spheronization of theophylline-Avicel combinations using a fluidized-bed rotoganulator technique. Drug Dev. Ind. Pharm. 1997, 23 (2), 173-182.
10. Matin, A. Micromeritics. In Physical Pharmacy, 4th Ed.; Matin, A., Ed.; Lea & Febiger: Philadelphia, 1993; 423-452.
11. Metha, H.A.; Kislalioglu, M.S.; Phuapradit, W.; Malick, A.W.; Shas, N.H. Effect of formulation and process varibles on porosity parameters and release rates from a multi unit erosion matrix of a poorly soluble drug. J. Control. Release 2000, 63, 201-211.
12. The United State Pharmacopeia 24/National Formulary 19. The United State Pharmacopeial Convention, Rockville, MD, 2000; 1629-1631.
13. Goodhart, F.M. Centrifugal equipment. In Pharmaceutical Pelletization Technology; Ghebre-Sellassie, I., Ed.; Marcel Dekker: New York, 1989; 101-122.
14. Suzuki, E.; Shimom, K.; Sekiguchi, K. Thermochemical study of theophylline and its hydrate. Chem. Pharm. Bull. 1989, 32 (2), 493-497.
15. Phadnis, N.V.; Suryanarayanan, R. Polymorphism in anhydrous theophylline implications on the dissolution rate of theophylline tablets. J. Pharm. Sci. 1997, 86 (11), 1256-1263.
16. Shefter, E.; Higuchi, T. Dissolution behavior of crystalline solvated and nonsolvated forms of some pharmaceuticals. J. Pharm. Sci. 1963, 52 (8), 781-791.