Reduced-intensity allogeneic stem cell transplantation for renal cell carcinoma: In vivo evidence of a graft-versus-tumor effect

Haematologica

Volumn 89, Issue 3, 2004, Pages 375-376

  Takami, Akiyoshi ^a,b   Asakura, Hidesaku ^a   Koshida, Kiyoshi ^b   Namiki, Mikio ^b   Nakao, Shinji ^a  

^a Department of Hematology ^*  (Japan)

^b KANAZAWA UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCE   (Japan)

Author keywords

Graft versus tumor effect; Reduced intensity stem cell transplantation; Renal cell carcinoma; Tumor infiltrating lymphocytes

Indexed keywords

CD8 ANTIGEN; CYCLOPHOSPHAMIDE; CYCLOSPORIN; CYTOKINE; FLUDARABINE; GRANULOCYTE COLONY STIMULATING FACTOR; INTERLEUKIN 2; STEROID;

ADULT; ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION; ARTICLE; CANCER REGRESSION; CHIMERA; CLEAR CELL CARCINOMA; CLINICAL ARTICLE; CLINICAL FEATURE; CYTOTOXIC T LYMPHOCYTE; DRUG RESPONSE; FEMALE; GRAFT VERSUS HOST REACTION; GRAFT VERSUS LEUKEMIA EFFECT; HISTOLOGY; HUMAN; KIDNEY CARCINOMA; MALE; METASTASIS; POLYMERASE CHAIN REACTION; SYMPTOM; TREATMENT OUTCOME;

AGED; CARCINOMA, RENAL CELL; FEMALE; GRAFT VS TUMOR EFFECT; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; KIDNEY NEOPLASMS; MALE; MIDDLE AGED; TISSUE DONORS; TRANSPLANTATION, HOMOLOGOUS;

EID: 2942714818     PISSN: 03906078     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (6)

1. Childs R, Chernoff A, Contentin N, Bahceci E, Schrump D, Leitman S, et al. Regression of metastatic renal-cell carcinoma after nonmyeloablative allogeneic peripheral-blood stem-cell transplantation. N Engl J Med 2000;343:750-8.
2. Bregni M, Dodero A, Peccatori J, Pescarollo A, Bernardi M, Sassi I, et al. Nonmyeloablative conditioning followed by hematopoietic cell allografting and donor lymphocyte infusions for patients with metastatic renal and breast cancer. Blood 2002;99:4234-6.
3. Hentschke P, Barkholt L, Uzunel M, Mattsson J, Wersall P, Pisa P, et al. Low-intensity conditioning and hematopoietic stem cell transplantation in patients with renal and colon carcinoma. Bone Marrow Transplant 2003;31:253-61.
4. Predrazzoli P, Da Prada GA, Giorgiani G, Schiavo R, Zambelli A, Giraldi E, et al. Allogeneic blood stem cell transplantation after a reduced-intensity, preparative regimen. Cancer 2002;94:2409-15.
5. Rini BI, Zimmerman T, Stadler WM, Gajewski TF, Vogelzang NJ. Allogeneic stem-cell transplantation of renal cell cancer after nonmyeloablative chemotherapy: feasibility, engraftment, and clinical results. J Clin Oncol 2002;20:2017-24.
6. Motzer RJ, Russo P. Systemic therapy for renal cell carcinoma. J Urol 2000;163:408-17.