Regioselective syntheses of 7-halogenated 7-deazapurine nucleosides related to 2-amino-7-deaza-2′-deoxyadenosine and 7-deaza-2′- deoxyisoguanosine

Synthesis

Volumn , Issue 8, 2004, Pages 1203-1210

  Seela, Frank ^a   Peng, Xiaohua ^a  

^a NONE

Author keywords

Glycosylations; Halogenation; Nucleosides; Pyrrolo 2,3 d pyrimidines; Regioselectivity; Sugar conformation

Indexed keywords

CONFORMATIONS; DERIVATIVES; NEGATIVE IONS; SUGARS; SYNTHESIS (CHEMICAL);

HALOGENATED DERIVATIVES; NUCLEOBASES;

AROMATIC COMPOUNDS;

2 AMINO 5,6 DIBROMO 4 CHLORO 7 [2 DEOXY 3,5 DI O (4 TOLUOYL) BETA DEXTRO ERYTHRO PENTOFURANOSYL] 7H PYRROLO[2,3 D]PYRIMIDINE; 4 AMINO 5 BROMO 7 (2 DEOXY BETA DEXTRO ERYTHRO PENTOFURANOSYL) 7H PYRROLO[2,3 D]PYRIMIDIN 2 ONE; 4 AMINO 5 CHLORO 7 (2 DEOXY BETA DEXTRO ERYTHRO PENTOFURANOSYL) 7H PYRROLO[2,3 D]PYRIMIDIN 2 ONE; 4 CHLORO 2 PIVALOYLAMINO 7H PYRROLO[2,3 D]PYRIMIDINE; 4 CHLORO 5 IODO 2 PIVALOYLAMINO 7H PYRROLO[2,3 D]PYRIMIDINE; 4 CHLORO 7 [2 DEOXY 3,5 BIS O (2 METHYLPROPANOYL) BETA DEXTRO ERYTHRO PENTOFURANOSYL] 2 (FORMYLAMINO) 5 IODO 7H PYRROLO[2,3 D]PYRIMIDINE; 4 CHLORO 7 [2 DEOXY 3,5 DI O (4 TOLUOYL) BETA DEXTRO ERYTHRO PENTOFURANOSYL] 2 PIVALOYLAMINO 7H PYRROLO[2,3 D]PYRIMIDINE; 4,5 DICHLORO 2 PIVALOYLAMINO 7H PYRROLO[2,3 D]PYRIMIDINE; 4,5 DICHLORO 7 [2 DEOXY 3,5 BIS O (2 METHYLPROPANOYL) BETA DEXTRO ERYTHRO PENTOFURANOSYL] 2 (FORMYLAMINO) 7H PYRROLO[2,3 D]PYRIMIDINE; 4,5 DICHLORO 7 [2 DEOXY 3,5 DI O (4 TOLUOYL) BETA DEXTRO ERYTHRO PENTOFURANOSYL] 2 PIVALOYLAMINO 7H PYRROLO[2,3 D]PYRIMIDINE; 5 BROMO 4 CHLORO 2 PIVALOYLAMINO 7H PYRROLO[2,3 D]PYRIMIDINE; 5 BROMO 4 CHLORO 7 [2 DEOXY 3,5 BIS O (2 METHYLPROPANOYL) BETA DEXTRO ERYTHRO PENTOFURANOSYL] 2 (FORMYLAMINO) 7H PYRROLO[2,3 D]PYRIMIDINE; 5 BROMO 4 CHLORO 7 [2 DEOXY 3,5 DI O (4 TOLUOYL) BETA DEXTRO ERYTHRO PENTOFURANOSYL] 2 PIVALOYLAMINO 7H PYRROLO[2,3 D]PYRIMIDINE; 5 BROMO 7 (2 DEOXY BETA DEXTRO ERYTHRO PENTOFURANOSYL) 7H PYRROLO[2,3 D]PYRIMIDINE 2,4 DIAMINE; 5 CHLORO 7 (2 DEOXY BETA DEXTRO ERYTHRO PENTOFURANOSYL) 7H PYRROLO[2,3 D]PYRIMIDINE 2,4 DIAMINE; 5,6 DIBROMO 7 (2 DEOXY BETA DEXTRO ERYTHRO PENTOFURANOSYL) 7H PYRROLO[2,3 D]PYRIMIDINE 2,4 DIAMINE; 7 (2 DEOXY BETA DEXTRO ERYTHRO PENTOFURANOSYL) 5 IODO 7H PYRROLO[2,3 D]PYRIMIDINE 2,4 DIAMINE; DEOXYADENOSINE DERIVATIVE; GUANOSINE DERIVATIVE; NUCLEOSIDE; PYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CONFORMATION; DRUG STRUCTURE; DRUG SYNTHESIS; GLYCOSYLATION; HALOGENATION; NUCLEAR MAGNETIC RESONANCE;

EID: 2942711907     PISSN: 00397881     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2004-822382     Document Type: Article

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