Hysterectomy versus expanded medical treatment for abnormal uterine bleeding: Clinical outcomes in the medicine or surgery trial

Obstetrics and Gynecology

Volumn 103, Issue 5 I, 2004, Pages 824-833

  Learman, Lee A ^a   Summitt Jr , Robert L ^b   Varner, R Edward ^b   Richter, Holly E ^b   Lin, Feng ^b   Ireland, Christine C ^b   Kuppermann, Miriam ^b   Vittinghoff, Eric ^b   Showstack, Jonathan ^b   Washington, A Eugene ^b   Hulley, Stephen B ^b  

^a SAN FRANCISCO GENERAL HOSPITAL   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ETHINYLESTRADIOL; GESTAGEN; IBUPROFEN; MEDROXYPROGESTERONE ACETATE; NAPROXEN; ORAL CONTRACEPTIVE AGENT; PROSTAGLANDIN INHIBITOR; ROFECOXIB;

ADULT; ARTICLE; CHRONICITY; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; FEMALE; HOT FLUSH; HUMAN; HYSTERECTOMY; IMPAIRED BLADDER EMPTYING; INTERMETHOD COMPARISON; MAJOR CLINICAL STUDY; MASTALGIA; OUTCOMES RESEARCH; PELVIS PAIN SYNDROME; PREMENOPAUSE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; SYMPTOMATOLOGY; TREATMENT PLANNING; UTERUS BLEEDING; VAGINA BLEEDING; COMPARATIVE STUDY; MIDDLE AGED; MULTICENTER STUDY; MULTIVARIATE ANALYSIS; QUALITY OF LIFE; TREATMENT OUTCOME;

ADULT; FEMALE; HUMANS; HYSTERECTOMY; MIDDLE AGED; MULTIVARIATE ANALYSIS; QUALITY OF LIFE; TREATMENT OUTCOME; UTERINE HEMORRHAGE;

EID: 2942707750     PISSN: 00297844     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.AOG.0000124272.22072.6f     Document Type: Article

References (16)

1. Farquhar CM, Steiner CA. Hysterectomy rates in the United States 1990 to 1997. Obstet Gynecol 2002;99: 229-34.
2. Carlson KJ, Miller BA, Fowler FJ Jr. The Maine Women's Health Study: I. Outcomes of hysterectomy. Obstet Gynecol 1994;83:556-65.
3. Kupperman M, Varner RE, Summitt RL, Learman LA, Ireland C, Vittinghoff E, et al. The effect of hysterectomy versus medical treatment on health-related quality of life and sexual functioning. The Medicine or Surgery (Ms) randomized trial. JAMA 2004;291:1447-55.
4. Varner RE, Ireland CC, Summitt RL, Richter HE, Learman LA, Vittinghoff E, et al. Medicine or Surgery (Ms): a randomized clinical trial comparing hysterectomy and medical treatment in premenopausal women with abnormal uterine bleeding. Controlled Clinical Trials 2004;25: 104-18.
5. McCulloch CE, Searle SR. Generalized, linear, and mixed models. New York (NY): John Wiley and Sons; 2001.
6. Cox DR, Oakes D. Analysis of survival data. London, UK: Chapman & Hall; 1984.
7. Ware J, Kosinski M, Keller S. SF-36 physical and mental health summary scales: a user's manual. Boston (MA): The Health Institute, New England Medical Center; 1994.
8. Myers ER, Steege JF. Risk adjustment for complications of hysterectomy: limitations of routinely collected administrative data. Am J Obstet Gynecol 1999;181:567-75.
9. Brown JS, Sawaya G, Thom DH, Grady D. Hysterectomy and urinary incontinence: a systematic review. Lancet 2000;356:535-9.
10. Rolnick SJ, Flores SK, Fowler SE, Derman R, Davidson B. Conducting randomized, controlled trials: experience with the dysfunctional uterine bleeding intervention trial [review]. J Reprod Med 2001;46:1-5, discussion 5-6.
11. Cooper KG, Grant AM, Garratt AM. The impact of using a partially randomized patient preference design when evaluating alternative managements for heavy menstrual bleeding. Br J Obstet Gynecol 1997;104:1367-73.
12. Broder MS, Landow WJ, Goodwin SC, Brook RH, Sherbourne CD, Harris K. An agenda for research into uterine artery embolization: results of an expert panel conference [review]. J Vasc Interverv Radiol 2000;11:509-15.
13. Marjoribanks J, Lethaby A, Farquhar C. Surgery versus medical therapy for heavy menstrual bleeding (Cochrane Review). In: The Cochrane Library, Issue 2, 2003. Oxford: Update Software.
14. Hurskainen R, Teperi J, Rissanen P, Aalto AM, Grenman S, Kivela A, et al. Quality of life and cost-effectiveness of levonorgestrel-releasing intrauterine system versus hysterectomy for treatment of menorrhagia: a randomized trial. Lancet 2001;357:273-7.
15. Cooper KG, Jack SA, Parkin DE, Grant AM. Five-year follow up of women randomized to medical management or transcervical resection of the endometrium for heavy menstrual loss: clinical and quality of life outcomes. BJOG 2001;108:1222-8.
16. Richter HE, Learman LA, Varner RE, Hendrix SL, Summitt RL, Washington AE. Medroxyprogesterone acetate for treatment of abnormal uterine bleeding: factors predicting success. Am J Obstet Gynecol 2003;189:37-42.