A randomized controlled trial of pemoline for attention-deficit/ hyperactivity disorder in substance-abusing adolescents

Journal of the American Academy of Child and Adolescent Psychiatry

Volumn 43, Issue 4, 2004, Pages 420-429

  Riggs, Paula D ^a   Hall, Shannon K ^a   Mikulich Gilbertson, Susan K ^a   Lohman, Michelle ^a   Kayser, Ashley ^a  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

Adolescent; Attention deficit hyperactivity disorder; Conduct disorder; Pemoline; Pharmacotherapy; Substance use disorder

Indexed keywords

LIVER ENZYME; PEMOLINE; PLACEBO; CENTRAL STIMULANT AGENT;

ADOLESCENT; ADULT; ARTICLE; ATTENTION DEFICIT DISORDER; CLINICAL TRIAL; COMORBIDITY; CONDUCT DISORDER; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE SEVERITY; DRUG EFFECT; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RATING SCALE; SUBSTANCE ABUSE; TREATMENT OUTCOME; ADDICTION; NONPARAMETRIC TEST; PSYCHIATRIC DIAGNOSIS; SAFETY;

ADOLESCENT; ADULT; ATTENTION DEFICIT DISORDER WITH HYPERACTIVITY; CENTRAL NERVOUS SYSTEM STIMULANTS; CONDUCT DISORDER; DIAGNOSIS, DUAL (PSYCHIATRY); FEMALE; HUMANS; MALE; PEMOLINE; SAFETY; STATISTICS, NONPARAMETRIC; SUBSTANCE-RELATED DISORDERS;

EID: 2942706090     PISSN: 08908567     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004583-200404000-00008     Document Type: Article

References (27)

1. Barrickman LL, Perry PJ, Allen AJ et al. (1995), Bupropion versus methylphenidate in the treatment of attention-deficit/hyperactivity disorder. J Am Acad Child Adolesc Psychiatry 34:649-657
2. Cohen J (1988), Statistical Power Analysis for the Behavioral Sciences, 2nd ed. Hillsdale, NJ: Lawrence Erlbaum Associates
3. Conners CK, Sitarenios G, Parker JD, Epstein JN (1998), The revised Conners' Parent Rating Scale (CPRS-R): factor structure, reliability, and criterion validity. J Abnorm Child Psychol 24:257-268
4. Cottler LB, Robins LN, Helzer JE (1989), The reliability of the CIDI-SAM: a comprehensive substance abuse interview. Br J Addict 84:801-814
5. Crowley TJ, Mikulich SK, Ehlers KM, Whitmore EA, Macdonald MJ (2001), Validity of structured clinical evaluations in adolescents with conduct and substance problems. J Am Acad Child Adolesc Psychiatry 40:265-273
6. Crowley TJ, Riggs PD (1995), Adolescent substance use disorder with conduct disorder and comorbid conditions. In: NIDA Research Monograph 156. Adolescent Drug Abuse: Clinical Assessment and Therapeutic Interventions, Vol 156, Rahdert E, Czechowicz D, eds. Rockville, MD: National Institute on Drug Abuse, pp 49-111
7. Daviss WB, Bentivoglio P, Racusin R, Brown KM, Bostic JQ, Wiley L (2001), Bupropion sustained release in adolescents with comorbid attention-deficit/ hyperactivity disorder and depression. J Am Acad Child Adolesc Psychiatry 40:307-314
8. Drug Strategies (2002), Treating Teens: A Guide to Adolescent Drug Programs. Washington, DC: Drug Strategies
9. Geller B, Cooper TB, Sun K et al. (1998), Double-blind and placebo-controlled study of lithium for adolescent bipolar disorders with secondary substance dependency. J Am Acad Child Adolesc Psychiatry 37:171-178
10. Greenhill LL, Swanson JM, Vitiello B et al. (2001), Impairment and deportment responses to different methylphenidate doses in children with ADHD: the MTA titration trial. J Am Acad Child Adolesc Psychiatry 40:180-187
11. Grella CE, Hser YI, Joshi V, Rounds-Bryant J (2001), Drug treatment outcomes for adolescents with comorbid mental and substance use disorders. J Nerv Ment Dis 189:384-392
12. Guy W (1976), ECDEU Assessment Manual for Psychopharmacology, Revised. Rockville, MD: National Institute of Mental Health, Dept. of Health Education and Welfare Publication (ADM)
13. Jensen PS, Rubio-Stipec M, Canino G et al. (1999), Parent and child contributions to diagnosis of mental disorder: are both informants always necessary? J Am Acad Child Adolesc Psychiatry 38:1569-1579
14. Klein-Schwartz W, McGrath J (2003), Poison centers' experience with methylphenidate abuse in pre-teens and adolescents. J Am Acad Child Adolesc Psychiatry 42:288-294
15. Ling W, Shoptaw S, Wesson D, Rawson RA, Compton M, Klett CJ (1997), Treatment Effectiveness Score as an Outcome Measure in Clinical Trials. NIDA Research Monograph 98-4125, pp 208-220
16. Lohman M, Riggs PD, Hall SK, Mikulich SK, Klein CA (2002), Perceived motivations for treatment in depressed, substance-dependent adolescents with conduct disorder. In: College on Problems of Drug Dependence: 64th Annual Scientific Meeting, Quebec City, Quebec, Canada, June 14-18
17. Markou A, Kosten TR, Koob GF (1998), Neurobiological similarities in depression and drug dependence: a self-medication hypothesis. Neuropsychopharmacology 18:135-174
18. Michelson D, Allen AJ, Busner J et al. (2002), Once-daily atomoxetine treatment for children and adolescents with attention deficit hyperactivity disorder: a randomized, placebo-controlled study. Am J Psychiatry 159:1896-1901
19. Riggs PD, Whitmore EA (1999), Substance use disorders and disruptive behavior disorders. In: Disruptive Behavior Disorders in Children and Adolescents, Hendren RL, ed. Washington, DC: APA Press, pp 133-173
20. Safer DJ, Zito JM, Gardner JF (2001), Pemoline hepatotoxicity and post-marketing surveillance. J Am Acad Child Adolesc Psychiatry 40:622-629
21. Schubiner H, Saules KK, Arfken CL et al. (2002), Double-blind placebo-controlled trial of methylphenidate in the treatment of adult ADHD patients with comorbid cocaine dependence. Exp Clin Psychopharmacol 10:286-294
22. Shaffer D, Fisher P, Lucas CP, Dulcan MK, Schwab-Stone ME (2000), NIMH Diagnostic Interview Schedule for Children Version IV (NIMH DISC-IV): description, differences from previous versions, and reliability of some common diagnoses. J Am Acad Child Adolesc Psychiatry 39:28-38
23. Solhkhah R, Wilens TE (1998), Pharmacotherapy of adolescent AOD use disorders. Alcohol Health Res World 22:122-126
24. Wilens TE, Faraone SV, Biederman J, Gunawardene S (2003), Does stimulant therapy of attention-deficit/hyperactivity disorder beget later substance abuse? A meta-analytic review of the literature. Pediatrics 111:179-185
25. Wilens TE, Spencer TJ, Biederman J et al. (2001), A controlled clinical trial of bupropion for attention deficit hyperactivity disorder in adults. Am J Psychiatry 158:282-288
26. Willy ME, Manda B, Shatin D, Drinkard CR, Graham DJ (2002), A study of compliance with FDA recommendations for pemoline (Cylert). J Am Acad Child Adolesc Psychiatry 41:785-790
27. Wise BK, Cuffe SP, Fischer T (2001), Dual diagnosis and successful participation of adolescents in substance abuse treatment. J Subst Abuse Treat 21:161-165