Inhibition of human pancreatic proteinases by human plasma α2-antiplasmin and antithrombin

Biological Chemistry

Volumn 385, Issue 5, 2004, Pages 423-427

  Nobar, Shila M ^a   Guy Crotte, Odette ^b   Rabaud, Michel ^a   Bieth, Joseph G ^a  

^a INSERM   (France)

^b AIX MARSEILLE UNIVERSITY   (France)

Author keywords

Heparin; Inhibition kinetics; Pancreatitis; Serpin

Indexed keywords

ALPHA 1 ANTICHYMOTRYPSIN; ALPHA 1 ANTITRYPSIN; ALPHA 2 ANTIPLASMIN; ANTITHROMBIN; CHYMOTRYPSIN; ELASTASE; LOW MOLECULAR WEIGHT HEPARIN; PANCREAS ENZYME; PLASMA PROTEIN; PROTEINASE; TRYPSIN;

ACUTE PANCREATITIS; ALPHA 1 ANTITRYPSIN DEFICIENCY; ARTICLE; CONTROLLED STUDY; ENZYME INHIBITION; ENZYME RELEASE; HUMAN; IN VIVO STUDY; PRIORITY JOURNAL; PROTEIN DEGRADATION; RISK ASSESSMENT; TIME;

ANTIPLASMIN; ANTITHROMBINS; CHYMOTRYPSIN; HUMANS; KINETICS; PANCREAS; SERINE PROTEINASE INHIBITORS;

EID: 2942706013     PISSN: 14316730     EISSN: None     Source Type: Journal    
DOI: 10.1515/BC.2004.048     Document Type: Article

References (33)

1. 1-antichymotrypsin. J. Biol. Chem. 255, 3931-3934.
2. Bieth, J.G. (1984). In vivo significance of kinetic constants of protein proteinase inhibitors. Biochem. Med. 32, 387-397.
3. Bieth, J.G. (1995). Theoretical and practical aspects of proteinase inhibition kinetics. Methods Enzymol. 248, 59-84.
4. Belorgey, D., Dirrig, S., Amouric, M., Figarella, C., and Bieth, J.G. (1996). Inhibition of human pancreatic proteinases by mucus proteinase inhibitor, eglin c and aprotinin. Biochem. J. 313, 555-560.
5. Bleeker, W.K., Agterberg, J., Rigter, G., Hack, C.E., and Gool, V.J. (1992). Protective effect of antithrombin III in acute experimental pancreatitis in rats. Digest. Dis. Sci. 37, 280285.
6. Cadène, M., Boudier, C., Daney de Marcillac, G., and Bieth, J.G. (1995). Influence of low molecular mass heparin on the kinetics of neutrophil elastase inhibition by mucus proteinase inhibitor. J. Biol. Chem. 270, 13204-13209.
7. Chase Jr., T., and Shaw, E. (1969). Comparison of the esterase activities of trypsin, plasmin, and thrombin on guanidino-benzoate esters. Titration of the enzymes. Biochemistry 8, 2212-2224.
8. Clemente, F., De Car, A., and Figarella, C. (1972). Composition du suc pancréatique humain. Eur. J. Biochem. 31, 186-193.
9. Crystal, R.G. (1996). α1-Antitrypsin Deficiency. Biology, Pathogenesis, Clinical Manifestations, Therapy (New York, USA: Marcel Dekker).
10. Danielsson, A., and Bjork, I. (1982). Mechanism of inactivation of trypsin by antithrombin. Biochem J. 207, 21-28.
11. 1-antichymotrypsin. Biochem. J. 245, 699-704.
12. Doutremepuich, C. (1992). Low Molecular Weight Heparins in Clinical Practice (New York, USA: Marcel Dekker).
13. Eriksson, S., Carlson, J., and Velez, R. (1986). Risk of cirrhosis and primary liver cancer in α1-antitrypsin deficiency. N. Engl. J. Med. 314, 736-739.
14. Faller, B., Dirrig, S., Rabaud, M., and Bieth, J.G. (1990). Kinetics of the inhibition of human pancreatic elastase by recombinant eglin c. Influence of elastin. Biochem. J. 270, 639-644.
15. Guy, O., Lombardo, D., Bartelt, D.C., Amic, J., and Figarella C. (1978). Two human trypsinogens. Purification, molecular properties, and N-terminal sequences. Biochemistry 17, 1669-1675.
16. 1-antitrypsin for structure and functions of serpins. Biochemistry 28, 8951-8966.
17. Jordan, R., Nelson, RM., Kilpatrick, J., Newgren, JO., Esmon, PC., and Fournel, M.A. (1989). Inactivation of human antithrombin by neutrophil elastase. J. Biol. Chem. 264, 10493-10500.
18. 1-antichymotrypsin is an inhibitor of pancreatic elastases. Eur. J. Biochem. 151, 327-331.
19. Largman, C., Brodrick, J., and Geokas, M. (1976). Purification and characterization of two human pancreatic elastases. Biochemistry 15, 2491-2499.
20. Largman, C., Brodrick, J.W., Geokas, M.C., and Johnson, J.H. (1978). Demonstration of human pancreatic anionic trypsinogen in normal serum by radioimmunoassay. Biochim. Biophys. Acta 543, 450-454.
21. Largman, C., Brodrick, J.W., Geokas, M.C., Johnson, J.H., and Fassett, M. (1980). Demonstration of a pancreatic proelastase 2-α 1-protease inhibitor complex in normal human plasma. Am. J. Physiol. 238, G177-G182.
22. Lasson, A. (1984). Acute pancreatitis in man. A clinical and biochemical study of pathophysiology and treatment. Scand. J. Gastroenterol. 19, 1-57.
23. Lasson, A., and Ohlsson, K. (1986). Disseminated intravascular coagulation and antiprotease activity in acute human pancreatitis. Scand. J. Gastroenterol. 21, 35-39.
24. Laurell, C.B., and Jeppsson, J.O. (1975). The Plasma Proteins, Structure, Function and Genetic Control. In: Plasma, F.W. Putnam, ad. (New York, USA: Academic Press), pp. 229-264.
25. Laurent, P., and Bieth, J.G. (1989). Kinetics of the inhibition of free and elastin-bound human pancreatic elastase by alpha 1-proteinase inhibitor and α2-macroglobulin. Biochim. Biophys. Acta 994, 285-288.
26. Mallory, P., and Travis, J. (1973). Human pancreatic enzymes. Characterization of anionic human trypsin. Biochemistry 12, 2847-2851.
27. Olson, S., and Shore, J. (1986). Transient kinetics of heparin-catalyzed protease inactivation by antithrombin III. J. Biol. Chem. 261, 13151-13159.
28. Silverman, G.A., Bird, P.I., Carrell, R.W., Church, F.C., Coughlin, P.B., Gettins, P.G., Irving, J.A., Lomas, D.A., Luke, C.J., Moyer, R.W. et al. (2001). The serpins are an expanding superfamily of structurally similar but functionally diverse proteins. Evolution, mechanism of inhibition, novel functions, and a revised nomenclature. J. Biol. Chem. 276, 33293-33298.
29. Schonbaum, G.R., Zerner, B., and Bender, M.L. (1961). The spectrophotometric determination of the operational normality of an alpha-chymotrypsin solution. J. Biol. Chem. 236, 2930-2935.
30. 2-antiplasmin. J. Biol. Chem. 262, 6055-6059.
31. Tietz, N.W., Borden, T., and Steppleton, J.D. (1959). An improved method for the determination of lipase in serum. Am. J. Clin. Pathol. 31, 148.
32. Travis, J., and Salvesen, G.S. (1983). Human plasma proteinase inhibitors. Annu. Rev. Biochem. 52, 655-709.
33. Yamagushi, H., Weidenbach, H., Lührs, H., Lerch, M.M., Dickneite, G., and Adler, G. (1997). Combined treatment with C1 esterase inhibitor and antithrombin III improves survival in severe acute experimental pancreatitis. Gut 40, 531-535.