Environmental pollutant tributyltin promotes Th2 polarization and exacerbates airway inflammation

European Journal of Immunology

Volumn 34, Issue 5, 2004, Pages 1312-1321

  Kato, Takuma ^a   Uchikawa, Ryuichi ^b   Yamada, Minoru ^b   Arizono, Naoki ^b   Oikawa, Saeko ^a   Kawanishi, Shosuke ^a   Nishio, Akiyoshi ^c   Nakase, Hiroshi ^c   Kuribayashi, Kagemasa ^a  

^a MIE UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^c KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Allergy; IL 10; IL 12; Pollutant; Th1; Th2

Indexed keywords

CD3 ANTIGEN; CD4 ANTIGEN; INTERLEUKIN 10; INTERLEUKIN 12; OVALBUMIN; PROTEIN ANTIBODY; TRIBUTYLTIN; ORGANOTIN COMPOUND;

AIR POLLUTANT; ANIMAL CELL; ANTIGEN PRESENTING CELL; ARTICLE; B LYMPHOCYTE; CELL MATURATION; CELL POLARITY; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; DISEASE EXACERBATION; FEMALE; IMMUNIZATION; MACROPHAGE; MOUSE; NEMATODIASIS; NIPPOSTRONGYLUS BRASILIENSIS; NONHUMAN; PRIORITY JOURNAL; PROVOCATION TEST; RESPIRATORY TRACT ALLERGY; RESPIRATORY TRACT INFLAMMATION; RISK ASSESSMENT; SENSITIZATION; SPLEEN CELL; T LYMPHOCYTE; TH1 CELL; TH2 CELL; ANIMAL; BRONCHUS; DRUG EFFECT; IMMUNOLOGY; INFLAMMATION; METABOLISM; POLLUTANT; SPLEEN;

ANIMALS; ANTIGEN-PRESENTING CELLS; B-LYMPHOCYTES; BRONCHI; ENVIRONMENTAL POLLUTANTS; INFLAMMATION; INTERLEUKIN-10; INTERLEUKIN-12; MICE; SPLEEN; TH2 CELLS; TRIALKYLTIN COMPOUNDS;

EID: 2942700005     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/eji.200324667     Document Type: Article

References (35)

1. Abbas, A. K., Murphy, K. M. and Sher, A., Functional diversity of helper T lymphocyte. Nature 1996. 383: 787-793.
2. O'Garra, A., Cytokines induce the development of functionally heterogenous T helper cell subsets. Cell 1998. 8: 275-283.
3. Skok, J., Poudrier, J. and Gray, D., Dendritic cell-derived IL-12 promotes B cell induction of Th2 differentiation: a feedback regulation of Th1 development. J. Immunol. 1999. 163: 4284-4291.
4. Moulin, V., Andris, F., Thielemans, K., Maliszewski, C., Urbain, J. and Moser, M., B lymphocytes regulate dendritic cell (DC) function in vivo: increased interleukin-12 production by DCs from B cell-deficient mice results in T helper cell type 1 deviation. J. Exp. Med. 2000. 192: 475-482.
5. + T cells to produce IL-4. J. Immunol. 1997. 158: 4171-4179.
6. + T cell responses: the alternative apporches. Annu. Rev. Immunol. 1997. 15: 297-322.
7. Romagnani, S., TH1 and TH2 in human diseases. Clin. Immunol. Immunopathol. 1996. 80: 225-235.
8. Holgate, S. T., The epidemic of allergy and asthma. Nature 1999. 402: B2-B4.
9. Yasdanbakhsh, M., Kremsner, P. G. and Ree, R. V., Allergy, parasites, and the hygiene hypothesis. Science 2002. 296: 490-494.
10. Whalen, M. M., Loganathan, B. G. and Kannan, K., Immunotoxicity of environmentally relevant concentrations of butyltins on numan natural keller cells in Vitro. Environ. Res. 1999. 81: 108-116.
11. Kannan, K., Tanabe, S. and Tatsukawa, R., Occurrence of butyltin residues in certain foodstuffs. Bull. Environ. Contam. Toxicol. 1995. 55: 510-516.
12. Snoeij, N. J., van Iersel, A. A. J., Penninks, A. H. and Seinen, W., Toxicity of triorganotin compounds: comparative in vivo studies with a series of trialkyltin compounds and triphenyltin chloride in male rats. Toxicol. Appl. Pharmacol. 1985. 81: 274-286.
13. Vos, J. G., Klerk, A. D., Krajnc, E. I., Kruizinga, W., Ommen, B. V. and Rozing, J., Toxicity of bis(tri-n-butyltin)oxide in the rat. II. Suppression of thymus-dependent immune responses and of parameters of nonspecific resistance after short-term exposure. Toxicol. Appl. Pharmacol. 1984. 75: 387-408.
14. Yamabe, Y., Hoshino, A., Imura, N., Suzuki, T. and Himeno, S., Enhancement of androgen-dependent transcription and cell proliferation by tributyltin and triphenyltin in human prostate cancer cells. Toxicol. Appl. Pharmacol. 2000. 169: 177-184.
15. Saitoh, M., Yanase, T., Morinaga, H., Tanabe, M., Mu, Y. M., Nishi, Y., Nomura, M., Okabe, T., Goto, K., Takayanagi, R. and Nawata, H., Tributyltin or triphenyltin inhibits aromatase activity in the human granulosa-like tumor cell line KGN. Biochem. Biophys. Res. Commun. 2001. 289: 198-204.
16. Bao, M., Yang, Y., Jun, H. S. and Yoon, J. W., Molecular mechanisms for gender differences in susceptibility to T cell-mediated autoimmune diabetes in nonobese diabetic mice. J. Immunol. 2002. 168: 5369-5375.
17. + T cell-intrinsic mechanism. J. Exp. Med. 1998. 188: 2289-2299.
18. Stridh, H., Cotgreave, I., Muller, M., Orrenius, S. and Gigliotti, D., Organotin-induced caspase activation and apoptosis in human peripheral blood lymphocytes. Chem. Res. Toxicol. 2001. 14: 791-798.
19. + T cells. J. Exp. Med. 1997. 185: 461-469.
20. Epstein, M. M., Di Rosa, F., Jankovic, D., Sher, A. and Matzinger, P., Successful T cell priming in B cell-deficient mice. J. Exp. Med. 1995. 182: 915-922.
21. Karulin, A. Y., Hesse, M. D., Yip, H. C. and Lehmann, P. V., Indirect IL-4 pathway in type I immunity. J. Immunol. 2002. 168: 545-553.
22. Maizels, R. M. and Holland, M. J., Parasite immunology: pathways for expelling intestinal helminths. Curr. Biol. 1998. 8: R711-714.
23. + T cells: IL-4 is essential for induction of antigen-specific antibody responses by TH2 but not TH1 clones. Eur. J. Immunol. 1990. 20: 2219-2227.
24. Varadhachary, A. S., Perdow, S. N., Hu, C., Ramanarayanan, M. and Salgame, P., Differential ability of T cell subsets to undergo activation-induced cell death. Proc. Natl. Acad. Sci. USA 1997. 94: 5778-5783.
25. Foey, A. D., Feldmann, M. and Brennan, F. M., CD40 ligation induces macrophage IL-10 and TNF-α production: Differential use of the PI3K and p42/44 MAPK-pathways. Cytokine 2001. 16: 131-142.
26. Aicher, A., Shu, L. G., Magaletti, D., Mulvania, T., Pezzutto, A., Craxton, A. and Clark, E. A., Differential role for p38 mitogen-activated protein kinase in regulating CD40-induced gene expression in dendritic cells and B cells. J. Immunol. 1999. 163: 5786-5795.
27. Banchereau, J. and Steinman, R. M., Dendritic cells and the control of immunity. Nature 1998. 392: 245-252.
28. Kushnir, N., Liu, L. and MacPherson, G. G., Dendritic cell and resting B cells from cultures in vitro and in vivo: T cell independence, partial LFA-1 dependence, and regulation by cross-linking surface molecules. J. Immunol. 1998. 160: 1774-1778.
29. Trinchieri, G., Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity. Annu. Rev. Immunol. 1995. 13: 251-276.
30. Kato, T., Hakamada, R., Yamane, H. and Nariuchi, H., Induction of IL-12 p40 messenger RNA expression and IL-12 production of macrophages via CD40-CD40 ligand interaction. J. Immunol. 1996. 156: 3932-3938.
31. Kato, T., Yamane, H. and Nariuchi, H., Differential effects of LPS and CD40 ligand stimulations on the induction of IL-12 prouction by dendritic cells and macrophages. Cell. Immunol. 1997. 181: 59-67.
32. Hino, A. and Nariuchi, H., Negative feedback mechanism suppresses interleukin-12 production by antigen-presenting cells interacting with T helper 2 cells. Eur. J. Immunol. 1996. 26: 623-628.
33. + T cells toward the Th1 subset by CTLA-4 costimulation. J. Immunol. 2000. 164: 3554-3562.
34. Yamane, H., Kato, T. and Nariuchi, H., Effective stimulation for IL-12 p35 mRNA accumulation and bioactive IL-12 production of antigen-presenting cells interacted with Th cells. J. Immunol. 1999. 162: 6433-6441.
35. Uchikawa, R., Matsuda, S. and Arizono, N., Suppression of gamma interferon transcription and production by nematode excretory-secretory antigen during polyclonal stimulation of rat lymph node T cells. Infect. Immun. 2000. 68: 6233-6239.