Degradation of raw or film-incorporated β-cyclodextrin by enzymes and colonic bacteria

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 58, Issue 1, 2004, Pages 91-97

  Fetzner, Axel ^a,b   Böhm, Stefan ^b,c   Schreder, Sven ^a   Schubert, Rolf ^b  

^a MERCK KGAA   (Germany)

^b Dept of Pharmaceutical Technology ^*  (Germany)

^c Pharmazeutisches Institut   (Germany)

Author keywords

cyclodextrin; 5 ASA, 5 aminosalicylic acid; BP, British pharmacopeia; CMC CL, sodium, sodium salt of crosslinked carboxymethylcellulose; Colon specific drug delivery; Colonic bacteria; Enzymatic degradation; Eudragit ; Film coating

Indexed keywords

AMYLASE; BETA CYCLODEXTRIN; BISOPROLOL; CARBOXYMETHYLCELLULOSE; EUDRAGIT; EXCIPIENT; GLYCOLYTIC ENZYME; MESALAZINE; POVIDONE IODINE; TALC;

ARTICLE; BACTERIAL STRAIN; COLON FLORA; COMPARATIVE STUDY; CROSS LINKING; DRUG COATING; DRUG DEGRADATION; DRUG DIFFUSION; DRUG FORMULATION; DRUG RELEASE; ENZYME DEGRADATION; ESCHERICHIA; FILM COATING; INCUBATION TIME; NONHUMAN; PROTEUS MIRABILIS; SERRATIA; TABLET FORMULATION;

ACRYLIC RESINS; ANIMALS; BETA-CYCLODEXTRINS; COLON; DIFFUSION; DRUG CARRIERS; SWINE;

EID: 2942665780     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2004.02.001     Document Type: Article

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