Chemical cleavage reactions of DNA on solid support: Application in mutation detection

BMC Chemical Biology

Volumn 3, Issue , 2003, Pages 1-6

  Bui, Chinh T ^a   Lambrinakos, Andreana ^a   Babon, Jeffrey J ^a   Cotton, Richard G H ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; DNA FRAGMENT; HYDROXYLAMINE; PERMANGANATE POTASSIUM; PIPERIDINE; SILICON DIOXIDE; TETRYLAMMONIUM CHLORIDE;

ANALYTIC METHOD; ARTICLE; CHEMICAL CLEAVAGE OF MISMATCH; CHEMICAL REACTION; CONTROLLED STUDY; DNA CLEAVAGE; DNA MODIFICATION; DNA PURIFICATION; IMMOBILIZATION; MOUSE; MUTATIONAL ANALYSIS; NONHUMAN;

EID: 2942650745     PISSN: 14726769     EISSN: None     Source Type: Journal    
DOI: 10.1186/1472-6769-3-1     Document Type: Article

References (13)

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3. Gogos JA, Karayiorgou M, Aburatani H and Kafatos FC Detection of single base mismatches of thymine and cytosine residues by potassium permanganate and hydroxylamine in the present of tetralkylammonium salts Nucleic Acids Res 1990, 18:6807-6814
4. Cotton RGH and Grompe M Chemical cleavage of heteroduplex DNA to identify mutations in Current Protocols in Human Genetic (Edited by: Dracopoli NC, Haines JL, Korf BR, Morton CC, Seidman CE, Seidman JG, Smith DR) John Wiley & Sons, Inc. Unit 7.6 1994,
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9. Cotton RGH Slowly, but surely towards better scanning for mutations Trends in genetics 1997, 13:43-46
10. Bui CT, Rees K, Lambrinakos A, Bedir A and Cotton RGH Site-selective reactions of imperfectly matched DNA with small chemical molecules: applications in mutation detection Bioorganic Chemistry 2002, 30:216-232
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