Comparative evaluation of Tc-99m-heat-denatured RBC and Tc-99m-anti-D IgG opsonized RBC spleen planar and SPECT scintigraphy in the detection of accessory spleen in postsplenectomy patients with chronic idiopathic thrombocytopenic purpura

Clinical Nuclear Medicine

Volumn 29, Issue 7, 2004, Pages 403-409

  Phom, Hentok ^a   Kumar, A ^a   Tripathi, M ^a   Chandrashekar, N ^a   Choudhry, V P ^a   Malhotra, A ^a   Bal, C S ^a  

^a ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

Accessory spleen; Chronic idiopathic thrombocytopenic purpura; Tc 99m heat denatured RBC and Tc 99m anti D IgG opsonized RBC spleen scintigraphy

Indexed keywords

ERYTHROCYTE TC 99M; HEAT DENATURED ERYTHROCYTE TC 99M; IMMUNOGLOBULIN G; RHESUS D ANTIBODY; RHESUS D ANTIBODY IMMUNOGLOBULIN G OPSONIZED ERYTHROCYTE TC 99M; TECHNETIUM 99M; UNCLASSIFIED DRUG;

ACCESSORY SPLEEN; ADOLESCENT; ADULT; AGED; ARTICLE; CHILD; CLINICAL ARTICLE; CLINICAL TRIAL; COLLIMATOR; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DRUG EFFICACY; FEMALE; HUMAN; IDIOPATHIC THROMBOCYTOPENIC PURPURA; MALE; PLANAR SCINTISCANNING; RADIOIMMUNOSCINTIGRAPHY; RANDOMIZED CONTROLLED TRIAL; RECURRENT DISEASE; SCINTILLATION CAMERA; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; SPLEEN SCINTISCANNING; SPLENECTOMY;

ADOLESCENT; ADULT; CHI-SQUARE DISTRIBUTION; CHILD; CHRONIC DISEASE; ERYTHROCYTES; FEMALE; FOLLOW-UP STUDIES; HUMANS; IMMUNOGLOBULIN G; ISOANTIBODIES; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; PURPURA, THROMBOCYTOPENIC, IDIOPATHIC; RADIOIMMUNODETECTION; RADIOPHARMACEUTICALS; RH-HR BLOOD-GROUP SYSTEM; SODIUM PERTECHNETATE TC 99M; SPLEEN; SPLENECTOMY; STATISTICS, NONPARAMETRIC; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON;

EID: 2942642532     PISSN: 03639762     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.rlu.0000129117.55170.fd     Document Type: Article

References (24)

1. McMillan R. Chronic idiopathic thrombocytopenic purpura: medical progress. N Engl J Med. 1981;304:1135.
2. Ahn YS, Harrington WJ. Treatment of idiopathic thrombocytopenic purpura. Annu Rev Med. 1977;28:299-309.
3. Defino SM, Lachant NA, Kirshner JJ, et al. Adult idiopathic thrombocytopenic purpura-clinical findings and response to therapy. Am J Med. 1980;69:430-442.
4. Olsen WR, Beaudoin DE. Increased incidence of accessory spleens in hematologic disease. Arch Surg. 1969;98:762-763.
5. Levine SP. Thrombocytopenia caused immunologic platelet destruction. In: Lee RG, Foerster J, et al. Wintrobes Clinical Hematology, vol 2, 10th ed. Baltimore: Williams & Wilkins; 1999:1583-1599.
6. Voet D, Afschrift M, Nachtegaele P, et al. Sonographic diagnosis of accessory spleen in recurrent ITP. Pediatr Radiol. 1983;13:2-3.
7. Beahrs JR, Stephens DH. Enlarged accessory spleens: CT appearance in post splenectomy patients. AJR Am J Roentgenol. 1980; 135:483-486.
8. Subramanyam BR, Balthazar EJ, Horri SC. Sonography of the accessory spleen. AJR Am J Roentgenol. 1984; 143:47-49.
9. Massey MD, Stevens JS. Residual spleen found on denatured RBC scan following negative colloid scan. J Nucl Med. 1991;32:2286-2287.
10. Ehrlich CP, Papanicolaou N, Treves S, et al. Splenic scintigraphy using Tc-99m-labeled heat-denatured red blood cells in pediatric patients: concise communication. J Nucl Med. 1982;23:209-213.
11. Ambriz P, Munoz R, Quintanar E, et al. Accessory spleen compromising response to splenectomy for ITP. Radiology. 1985; 155:793-796.
12. Pohlson EC, Wilkinson RW, Witzum KF, et al. Heat damaged red cell scan for intraoperative localization of accessory spleen. J Pediatr Surg. 1994;29:604-608.
13. Armas RR, Thakur ML, Gottshalk A. A simplified method of selective spleen scintigraphy with 99mTc labeled erythrocytes: clinical application. Concise communication. J Nucl Med. 1980;21:413-416.
14. Ramchandran T, Margouleff D, Atkins H. Spleen scanning in humans with Tc-99m-labeled erythrocytes: concise communication. J Nucl Med. 1980;21:13-16.
15. Van Nostrand D, Corley JH, Kyle RW, et al. Value of selective spleen scintigraphy when liver/spleen image shows equivocal spleen defects. Concise communication. J Nucl Med. 1983;24:559-562.
16. Phom H, Dasan B, Kasyap R, et al. Detection of multiple accessory spleens in a patient with chronic idiopathic thrombocytopenic purpura. Clin Nucl Med. 2001;26:593-595.
17. Gottschalk A. Heat denatured RBC SPECT imaging facilitated the visualisation of more than 13 spleens. Year book of Nuclear Medicine. Mosby Inc., St. Louis. 2002:157-158.
18. Aster RH, Keene WR. Sites of platelet destruction in idiopathic thrombocytopenic purpura. Br J Haematol. 1969; 16:61.
19. Morrison M, Lederer M, Fradkin WZ. Accessory spleen-their significance in essential thrombocytopenic purpura hemorrhagica. Am J Med Sci. 1928;176:672.
20. Witold J, Rudowski MD. Accessory spleen: clinical significance with particular reference to the recurrence of ITP. World J Surg. 1985;9:422.
21. Eraklis AJ, Filler RM. Splenectomy in childhood: a review of 1413 cases. Paediatr Surg. 1972;7:382-385.
22. Wallace D, Fromm D, Thomas D. Accessory splenectomy for idiopathic thrombocytopenic purpura. Surgery. 1982;91:135.
23. Frank MM, Lawley TJ, Humburger MI, et al. Immunoglobulin G Fc receptor-mediated clearance in autoimmune diseases. Ann Intern Med. 1983;98:206-218.
24. Kelton JG, Gibbons S. Autoimmune platelet destruction: idiopathic thrombocytopenic purpura. Semin Thromb Hemost. 1982;8:83-104.