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1
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2942657849
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ALTANA and Pharmacia to collaborate in development and commercialization of respiratory disease product candidate
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ALTANA AG, Pharmacia Corporation. Media Release: 22 Apr Available from URL:
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ALTANA AG, Pharmacia Corporation. ALTANA and Pharmacia to collaborate in development and commercialization of respiratory disease product candidate. Media Release: 22 Apr 2002. Available from URL: http://www.altana.com
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(2002)
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2
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2942685836
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ALTANA and Tanabe Seiyaku sign Roflumilast cooperation in the Japanese Market
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ALTANA AG, Tanabe Sciyaku Co Ltd. Media Release: 15 Nov Available from URL:
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ALTANA AG, Tanabe Sciyaku Co Ltd. ALTANA and Tanabe Seiyaku sign Roflumilast cooperation in the Japanese Market. Media Release: 15 Nov 2002. Available from URL: http://www.altanapharma.com
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(2002)
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3
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2942655617
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ALTANA completes another phase III study on Roflumilast in COPD patients
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ALTANA AG. Media Release: 10 Sep Available from URL:
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ALTANA AG. ALTANA completes another phase III study on Roflumilast in COPD patients. Media Release: 10 Sep 2003. Available from URL: http://www.altanapharma.com
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(2003)
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4
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2942677442
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Roflumilast, a novel, oral, selective PDE4 inhibitor, shows high absolute bioavailability
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Feb
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David M, Zech K, Seiberling M, et al. Roflumilast, a novel, oral, selective PDE4 inhibitor, shows high absolute bioavailability. Journal of Allergy and Clinical Immunology 113 (Suppl.): 220-1, No. 2, Feb 2004
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(2004)
Journal of Allergy and Clinical Immunology
, vol.113
, Issue.2 SUPPL.
, pp. 220-221
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David, M.1
Zech, K.2
Seiberling, M.3
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5
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2942651157
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Pharmacokinetic characteristics of roflumilast administered in gradually increasing doses of 500microg to 1000microg are dose-linear in healthy subjects
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(plus poster), Sep
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Manegold A, Hauns B, David M, et al. Pharmacokinetic characteristics of roflumilast administered in gradually increasing doses of 500microg to 1000microg are dose-linear in healthy subjects. European Respiratory Journal Supplement 20 (Suppl. 38): 108 (plus poster), Sep 2002
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(2002)
European Respiratory Journal Supplement
, vol.20
, Issue.SUPPL. 38
, pp. 108
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Manegold, A.1
Hauns, B.2
David, M.3
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6
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2942679698
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Pharmacokinetics of roflumilast and its active metabolite roflumilast-N-oxide in middle aged and young subjects
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(plus poster), Sep
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Manegold A, Huennemayer A, Zech K, et al. Pharmacokinetics of roflumilast and its active metabolite roflumilast-N-oxide in middle aged and young subjects. European Respiratory Journal Supplement 20 (Suppl. 38): 109 (plus poster), Sep 2002
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(2002)
European Respiratory Journal Supplement
, vol.20
, Issue.SUPPL. 38
, pp. 109
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Manegold, A.1
Huennemayer, A.2
Zech, K.3
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7
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2942631580
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Patients with severe renal impairment do not require dose adjustment of roflumilast
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(plus poster), Sep
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Drollmann A, Hartmann M, Zech K, et al. Patients with severe renal impairment do not require dose adjustment of roflumilast. European Respiratory Journal Supplement 20 (Suppl. 38): 108-9 (plus poster), Sep 2002
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(2002)
European Respiratory Journal Supplement
, vol.20
, Issue.SUPPL. 38
, pp. 108-109
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Drollmann, A.1
Hartmann, M.2
Zech, K.3
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8
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0000041474
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Safety and efficacy of the new PDE4 inhibitor roflumilast administered to patients with exercise-induced asthma over 4 weeks
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(plus poster), Mar
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Timmer W, Leclerc V, Birraux G, et al. Safety and efficacy of the new PDE4 inhibitor roflumilast administered to patients with exercise-induced asthma over 4 weeks. American Journal of Respiratory and Critical Care Medicine 161 (Suppl.): 505 (plus poster), Part 2, Mar 2000
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(2000)
American Journal of Respiratory and Critical Care Medicine
, vol.161
, Issue.SUPPL. and PART 2
, pp. 505
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Timmer, W.1
Leclerc, V.2
Birraux, G.3
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9
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0242375405
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Roflumilast, a new, orally active, selective phosphodiesterase 4 inhibitor, is safe and well tolerated in patients with chronic obstructive pulmonary disease
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(plus poster), Sep
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Leichtl S, Syed J, Bredenbröker D, et al. Roflumilast, a new, orally active, selective phosphodiesterase 4 inhibitor, is safe and well tolerated in patients with chronic obstructive pulmonary disease. European Respiratory Journal Supplement 20 (Suppl. 38): 303 (plus poster), Sep 2002
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(2002)
European Respiratory Journal Supplement
, vol.20
, Issue.SUPPL. 38
, pp. 303
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Leichtl, S.1
Syed, J.2
Bredenbröker, D.3
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10
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2942692357
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RECORD Study shows new Roflumilast data in COPD patients
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ALTANA AG. Media Release: 28 Sep Available from URL:
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ALTANA AG. RECORD Study shows new Roflumilast data in COPD patients. Media Release: 28 Sep 2003. Available from URL: http://www.altanapharma.com
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(2003)
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11
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0001747287
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Acute anti-inflammatory effect of the novel phosphodiesterase 4 inhibitor roflumilast on allergen challenge in asthmatics after a single dose
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Mar
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Nell H, Louw C, Leichtl S, et al. Acute anti-inflammatory effect of the novel phosphodiesterase 4 inhibitor roflumilast on allergen challenge in asthmatics after a single dose. American Journal of Respiratory and Critical Care Medicine 161 (Suppl.): 200, Part 2, Mar 2000
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(2000)
American Journal of Respiratory and Critical Care Medicine
, vol.161
, Issue.SUPPL. and PART 2
, pp. 200
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Nell, H.1
Louw, C.2
Leichtl, S.3
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12
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0003278158
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Four-week treatment with the new PDE4 inhibitor roflumilast in patients with exercise-induced asthma: Safety, efficacy and inhibition of TNF-alpha ex vivo
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Aug
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Hauns B, Leclerc V, Birraux G, et al. Four-week treatment with the new PDE4 inhibitor roflumilast in patients with exercise-induced asthma: safety, efficacy and inhibition of TNF-alpha ex vivo. European Respiratory Journal Supplement 16 (Suppl. 31): 540, Aug 2000
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(2000)
European Respiratory Journal Supplement
, vol.16
, Issue.SUPPL. 31
, pp. 540
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Hauns, B.1
Leclerc, V.2
Birraux, G.3
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13
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0036179542
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The new phosphodiesterase 4 inhibitor roflumilast is efficacious in exercise-induced asthma and leads to suppression of LPS-stimulated TNF-alpha ex vivo
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Mar
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Timmer W, Leclerc V, Birraux G, et al. The new phosphodiesterase 4 inhibitor roflumilast is efficacious in exercise-induced asthma and leads to suppression of LPS-stimulated TNF-alpha ex vivo. Journal of Clinical Pharmacology 42: 297-303, Mar 2002
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(2002)
Journal of Clinical Pharmacology
, vol.42
, pp. 297-303
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Timmer, W.1
Leclerc, V.2
Birraux, G.3
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14
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2942696689
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Roflumilast, a selective phosphodiesterase 4 inhibitor reduces late phase asthma and hyperresponsiveness
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Mar
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Louw C, Williams Z, Leichtl S, et al. Roflumilast, a selective phosphodiesterase 4 inhibitor reduces late phase asthma and hyperresponsiveness. Respirology 7 (Suppl.): 22, Mar 2002
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(2002)
Respirology
, vol.7
, Issue.SUPPL.
, pp. 22
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Louw, C.1
Williams, Z.2
Leichtl, S.3
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15
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0242312410
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Roflumilast, a new, orally active, selective phosphodiesterase 4 inhibitor, is effective in the treatment of asthma
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(plus poster), Sep
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Leichtl S, Schmid-Wirlitsch C, Bredenbröker D, et al. Roflumilast, a new, orally active, selective phosphodiesterase 4 inhibitor, is effective in the treatment of asthma. European Respiratory Journal Supplement 20 (Suppl. 38): 303 (plus poster), Sep 2002
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(2002)
European Respiratory Journal Supplement
, vol.20
, Issue.SUPPL. 38
, pp. 303
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Leichtl, S.1
Schmid-Wirlitsch, C.2
Bredenbröker, D.3
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16
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2942638301
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Dose-dependent inhibitory effect of roflumilast, a new, orally active, selective phophodiesterase 4 inhibitor, on allergen-induced early and late asthmatic reaction
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(plus poster), Sep
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van Schalkwyk EM, van Heerden K, Bredenbröker D, et al. Dose-dependent inhibitory effect of roflumilast, a new, orally active, selective phophodiesterase 4 inhibitor, on allergen-induced early and late asthmatic reaction. European Respiratory Journal Supplement 20 (Suppl. 38): 110 (plus poster), Sep 2002
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(2002)
European Respiratory Journal Supplement
, vol.20
, Issue.SUPPL. 38
, pp. 110
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van Schalkwyk, E.M.1
van Heerden, K.2
Bredenbröker, D.3
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17
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2942657850
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ALTANA Pharma Presents Studies of Roflumilast at the American Thoracic Society International Conference
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ALTANA Pharma. Media Release: 21 May Available from URL:
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ALTANA Pharma. ALTANA Pharma Presents Studies of Roflumilast at the American Thoracic Society International Conference. Media Release: 21 May 2003. Available from URL: http://www.altanapharma.com
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(2003)
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18
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2942688016
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Additional Positive Roflumilast Data of RECORD Study at German Congress for Pneumonology
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Altana AG. Media Release: 12 Mar Available from URL:
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Altana AG. Additional Positive Roflumilast Data of RECORD Study at German Congress for Pneumonology. Media Release: 12 Mar 2004. Available from URL: http://www.altana.com
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(2004)
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