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Volumn 42, Issue 2, 2004, Pages 149-152

Reduced toxicity of acetaminophen in children: It's the liver

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; CYTOCHROME P450; GLUTATHIONE; PARACETAMOL;

EID: 2942627118     PISSN: 07313810     EISSN: None     Source Type: Journal    
DOI: 10.1081/CLT-120030940     Document Type: Note
Times cited : (13)

References (22)
  • 3
    • 0034047901 scopus 로고    scopus 로고
    • Unintentional acetaminophen ingestion in children and the potential for hepatotoxicity
    • Caravati EM. Unintentional acetaminophen ingestion in children and the potential for hepatotoxicity. J Toxicol, Clin Toxicol 2000; 38:291-296.
    • (2000) J Toxicol, Clin Toxicol , vol.38 , pp. 291-296
    • Caravati, E.M.1
  • 5
    • 0036226892 scopus 로고    scopus 로고
    • Acetaminophen hepatotoxicity: The first 35 years
    • Rumack BH. Acetaminophen hepatotoxicity: the first 35 years. J Toxicol, Clin Toxicol 2002; 40:3-20.
    • (2002) J Toxicol, Clin Toxicol , vol.40 , pp. 3-20
    • Rumack, B.H.1
  • 6
    • 0025953515 scopus 로고
    • Acetaminophen overdose: A 48-hour intravenous N-acetylcysteine treatment protocol
    • Smilkstein MJ, Bronstein AC, Linden C, et al. Acetaminophen overdose: a 48-hour intravenous N-acetylcysteine treatment protocol. Ann Emerg Med 1991; 20:1058-1063.
    • (1991) Ann Emerg Med , vol.20 , pp. 1058-1063
    • Smilkstein, M.J.1    Bronstein, A.C.2    Linden, C.3
  • 7
    • 0024262737 scopus 로고
    • Efficacy of oral N-acetylcysteine in the treatment of acetaminophen overdose. Analysis of the national multicenter study (1976 to 1985)
    • Smilkstein MF, Knapp GL, Kulig DW, et al. Efficacy of oral N-acetylcysteine in the treatment of acetaminophen overdose. Analysis of the national multicenter study (1976 to 1985). N Engl J Med 1988; 319:1557-1562.
    • (1988) N Engl J Med , vol.319 , pp. 1557-1562
    • Smilkstein, M.F.1    Knapp, G.L.2    Kulig, D.W.3
  • 8
    • 0026594498 scopus 로고
    • Single-dose pharmacokinetics of ibuprofen and acetaminophen in febrile children
    • Brown RD, Wilson JT, Kearns GL, et al. Single-dose pharmacokinetics of ibuprofen and acetaminophen in febrile children. J Clin Pharmacol 1992; 32:231-241.
    • (1992) J Clin Pharmacol , vol.32 , pp. 231-241
    • Brown, R.D.1    Wilson, J.T.2    Kearns, G.L.3
  • 9
    • 0017228166 scopus 로고
    • Acetaminophen elimination kinetics in neonates, children and adults
    • Miller RP, Roberts RJ, Fisher LJ. Acetaminophen elimination kinetics in neonates, children and adults. Clin Pharmacol Ther 1976; 19:284-294.
    • (1976) Clin Pharmacol Ther , vol.19 , pp. 284-294
    • Miller, R.P.1    Roberts, R.J.2    Fisher, L.J.3
  • 10
    • 0021733877 scopus 로고
    • Sources of interindividual variation in acetaminophen and antipyrine metabolism
    • Nash RM, Stein L, Penno MB, et al. Sources of interindividual variation in acetaminophen and antipyrine metabolism. Clin Pharmacol Ther 1984; 36:417-430.
    • (1984) Clin Pharmacol Ther , vol.36 , pp. 417-430
    • Nash, R.M.1    Stein, L.2    Penno, M.B.3
  • 11
    • 0022979310 scopus 로고
    • Inter-subject and ethnic differences in paracetamol metabolism
    • Critchley JAJH, Nimmo GR, Gregson CA, et al. Inter-subject and ethnic differences in paracetamol metabolism. Br J Pharmacol 1986; 22:649-657.
    • (1986) Br J Pharmacol , vol.22 , pp. 649-657
    • Critchley, J.A.J.H.1    Nimmo, G.R.2    Gregson, C.A.3
  • 12
    • 0026568943 scopus 로고
    • Influence of age dependent pharmacokinetics and metabolism on acetaminophen hepatotoxicity
    • Rumore MM, Blaiklock RG. Influence of age dependent pharmacokinetics and metabolism on acetaminophen hepatotoxicity. J Pharm Sci 1992; 81:203-207.
    • (1992) J Pharm Sci , vol.81 , pp. 203-207
    • Rumore, M.M.1    Blaiklock, R.G.2
  • 14
    • 0029998776 scopus 로고    scopus 로고
    • Metabolism of paracetamol in children with chronic liver disease
    • Al-Obaidy SS, McKieman PJ, Po AWL, et al. Metabolism of paracetamol in children with chronic liver disease. Eur J Pharmacol 1996; 50:69-76.
    • (1996) Eur J Pharmacol , vol.50 , pp. 69-76
    • Al-Obaidy, S.S.1    McKieman, P.J.2    Po, A.W.L.3
  • 15
  • 16
    • 0018822416 scopus 로고
    • The effects of age and glutathione depletion on hepatic glutathione turnover in vivo determined by acetaminophen probe analysis
    • Lauterburg BH, Vaishnav Y, Stillwell WG, et al. The effects of age and glutathione depletion on hepatic glutathione turnover in vivo determined by acetaminophen probe analysis. J Pharmacol Exp Ther 1980; 213:54-58.
    • (1980) J Pharmacol Exp Ther , vol.213 , pp. 54-58
    • Lauterburg, B.H.1    Vaishnav, Y.2    Stillwell, W.G.3
  • 17
    • 0023009319 scopus 로고
    • Prediction of acetaminophen level from clinical history of overdose using a pharmacokinetic model
    • Edwards DA, Fish SF, Lamson MJ, et al. Prediction of acetaminophen level from clinical history of overdose using a pharmacokinetic model. Ann Emerg Med 1986; 15(11):1314-1319.
    • (1986) Ann Emerg Med , vol.15 , Issue.11 , pp. 1314-1319
    • Edwards, D.A.1    Fish, S.F.2    Lamson, M.J.3
  • 18
    • 0019504442 scopus 로고
    • Age as a variable in acetaminophen overdose
    • Peterson RG, Rumack BH. Age as a variable in acetaminophen overdose. Arch Intern Med 1981; 141:390-393.
    • (1981) Arch Intern Med , vol.141 , pp. 390-393
    • Peterson, R.G.1    Rumack, B.H.2
  • 19
    • 0019978073 scopus 로고
    • Efficacy, disposition, and pharmacodynamics of aspirin, acetaminophen and choline salicylate in young febrile children
    • Wilson JT, Brown RD, Bocchini JA, et al. Efficacy, disposition, and pharmacodynamics of aspirin, acetaminophen and choline salicylate in young febrile children. Ther Drug Monit 1982; 4:147-180.
    • (1982) Ther Drug Monit , vol.4 , pp. 147-180
    • Wilson, J.T.1    Brown, R.D.2    Bocchini, J.A.3
  • 20
    • 0026774994 scopus 로고
    • Pharmacokinetics and pharmacodynamics of ibuprofen isomers and acetaminophen in febrile children
    • Kelley MT, Walson PD, Edge JH, et al. Pharmacokinetics and pharmacodynamics of ibuprofen isomers and acetaminophen in febrile children. Clin Pharmacol Ther 1992; 52:181-189.
    • (1992) Clin Pharmacol Ther , vol.52 , pp. 181-189
    • Kelley, M.T.1    Walson, P.D.2    Edge, J.H.3
  • 21
    • 0027301279 scopus 로고
    • Influence of time until emesis on the efficacy of decontamination using acetaminophen as a marker in a pediatric population
    • Bond GR, Requa RK, Krenzelok EP, et al. Influence of time until emesis on the efficacy of decontamination using acetaminophen as a marker in a pediatric population. Ann Emerg Med 1993; 22:1403-1407.
    • (1993) Ann Emerg Med , vol.22 , pp. 1403-1407
    • Bond, G.R.1    Requa, R.K.2    Krenzelok, E.P.3
  • 22
    • 0033872088 scopus 로고    scopus 로고
    • Prospective evaluation of home treatment of mild to moderate pediatric acetaminophen exposures
    • Mohler CR, Nordt SP, Williams SR, Manoguerra A, Clark RF. Prospective evaluation of home treatment of mild to moderate pediatric acetaminophen exposures. Ann Emerg Med 2000; 35:239-244.
    • (2000) Ann Emerg Med , vol.35 , pp. 239-244
    • Mohler, C.R.1    Nordt, S.P.2    Williams, S.R.3    Manoguerra, A.4    Clark, R.F.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.