A monozygotic twin pair discordant for narcolepsy and CSF hypocretin-1

Neurology

Volumn 62, Issue 11, 2004, Pages 2137-2138

  Dauvilliers, Yves ^a,b,c   Maret, S ^c   Bassetti, C ^d   Carlander, B ^a   Billiard, M ^a   Touchon, J ^a,b   Tafti, M ^c  

^a GUI DE CHAULIAC HOSPITAL   (France)

^b Montpellier 1 University   (France)

^c GENEVA UNIVERSITY HOSPITALS   (Switzerland)

^d UNIVERSITY HOSPITAL ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

HLA DQB1 ANTIGEN; MODAFINIL; OREXIN A; VENLAFAXINE;

ADULT; ARTICLE; CASE REPORT; CATAPLEXY; CEREBROSPINAL FLUID ANALYSIS; CLINICAL FEATURE; FEMALE; GENETIC ASSOCIATION; HEREDITY; HOMOZYGOSITY; HUMAN; HYPERSOMNIA; HYPNAGOGIC HALLUCINATION; MONOZYGOTIC TWINS; NARCOLEPSY; PARASOMNIA; POLYSOMNOGRAPHY; PRIORITY JOURNAL; SOMNOLENCE; TWIN DISCORDANCE;

EID: 2942624342     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/WNL.62.11.2137     Document Type: Article

References (7)

1. Mignot E. Genetic and familial aspects of narcolepsy. Neurology 1998;50:16-22.
2. Mignot E, Lammers GJ, Ripley B, et al. The role of cerebrospinal fluid hypocretin measurement in the diagnosis of narcolepsy and other hypersomnias. Arch Neurol 2002;59:1553-1562.
3. Peyron C, Faraco J, Rogers W, et al. A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains. Nat Med 2000;6:991-997.
4. Khatami R, Maret S, Werth E, et al. A monozygotic twin pair concordant for narcolepsy-cataplexy without any detectable abnormality in the hypocretin (orexin) pathway. Lancet 2004 (in press).
5. Dauvilliers Y, Montplaisir J, Molinari N, et al. Age at onset of narcolepsy in two large populations of patients in France and Quebec. Neurology 2001;57:2029-2033.
6. Kubota H, Kanbayashi T, Tanabe Y, et al. Decreased cerebrospinal fluid hypocretin-1 levels near the onset of narcolepsy in 2 prepubertal children. Sleep 2003;26:555-557.
7. Honda M, Honda Y, Uchida S, et al. Monozygotic twins incompletely concordant for narcolepsy. Biol Psychiatry 2001;49:943-947.