Piperacillin induced bone marrow suppression: A case report

BMC Clinical Pharmacology

Volumn 3, Issue , 2003, Pages

  Kumar, Ashish ^a   Choudhuri, Gourdas ^a   Aggarwal, Rakesh ^a  

^a SANJAY GANDHI POSTGRADUATE INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

[No Author keywords available]

Indexed keywords

AMIKACIN; ANTIBIOTIC AGENT; CIPROFLOXACIN; METRONIDAZOLE; PIPERACILLIN; PIPERACILLIN PLUS TAZOBACTAM; ANTIINFECTIVE AGENT;

ADULT; ARTICLE; BLOOD ANALYSIS; BONE MARROW SUPPRESSION; CASE REPORT; DRUG SAFETY; DRUG SENSITIVITY; FEVER; HUMAN; MALE; NEUTROPENIA; PANCREAS PSEUDOCYST; PRESCRIPTION; THROMBOCYTOPENIA; TREATMENT OUTCOME; BONE MARROW DISEASE; CHEMICALLY INDUCED DISORDER;

ADULT; ANTI-BACTERIAL AGENTS; BONE MARROW DISEASES; HUMANS; MALE; PIPERACILLIN;

EID: 2942612290     PISSN: 14726904     EISSN: 14726904     Source Type: Journal    
DOI: 10.1186/1472-6904-3-2     Document Type: Article

References (18)

1. Kaucers A, Crowe SM, Grayson ML, Hoy JF and ed: The use of antibiotics: A clinical review of antibacterial, antifungal and antiviral drugs Oxford: Butterworth Heinemann 1997.
2. Winston DJ, Murphy W, Young LS and Hewitt WL: Piperacillin therapy for serious bacterial infections Am J Med 1980, 69:255-261.
3. Lutz B, Mogabgab W, Holmes B, Pollock B and Beville R: Clinical evaluation of the therapeutic efficacy and tolerability of piperacillin Antimicrob Agents Chemother 1982, 22:10-14.
4. Bressler RB and Huston DP: Piperacillin-induced anemia and leukopenia South Med J 1986, 79:255-256.
5. Kirkwood CF and Lasezkay GM: Neutropenia associated with mezlocillin and piperacillin Drug Intell Clin Pharm 1985, 19:112-114.
6. Sugimoto M, Wakabayashi Y and Shiokawa Y: A case of piperacillin induced leucopenia whose CFU-C derived colony was inhibited in vitro by the coexisting addition of drug, serum, and mononuclear cells Rinsho Ketsueki 1984, 25:197-202.
7. Wilson C, Greenhood G, Remington JS and Vosti KL: Neutropenia after consecutive treatment courses with nafcillin and piperacillin Lancet 1979, 1:1150.
8. Reichardt P, Handrick W, Linke A, Schille R and Kiess W: Leukocytopenia, thrombocytopenia and fever related to piperacillin/tazobactam treatment - a retrospective analysis in 38 children with cystic fibrosis Infection 1999, 27:355-356.
9. Ruiz-Irastorza G, Barreiro G and Aguirre C: Reversible bone marrow depression by high-dose piperacillin/tazobactam Br J Haematol 1996, 95:611-612.
10. Gerber L and Wing EJ: Life-threatening neutropenia secondary to piperacillin/tazobactam therapy Clin Infec Dis 1995, 21:1047-1048.
11. Neftel KA, Hauser SP and Müller MR: Inhibition of granulopoiesis in vivo and in vitro by beta-lactam antibiotics J Infect Dis 1985, 152:90-98.
12. Singh N, Yu VL, Mieles LA and Wagener MM: Beta-lactam antibiotic-induced leukopenia in severe hepatic dysfunction: risk factors and implications for dosing in patients with liver disease Am J Med 1993, 94:251-256.
13. Thickett KM, Wildman MJ, Fegan CD and Stableforth DE: Haemolytic anaemia following treatment with piperacillin in a patient with cystic fibrosis J Antimicrob Chemother 1999, 43:435-436.
14. Olivera E, Lakhani P and Watanakunakorn C: Isolated severe thrombocytopenia and bleeding caused by piperacillin Scand J Infect Dis 1992, 24:815-817.
15. Fass RJ, Copelan EA, Brandt JT, Moeschberger ML and Ashton JJ: Platelet-mediated bleeding caused by broad-spectrum penicillins J Infect Dis 1987, 155:1242-1248.
16. Moore M, McNamara TR and Johnson J: Elevated bleeding time and epistaxis associated with piperacillin therapy South Med J 1985, 78:363.
17. Yata Y, Miyagiwa M, Inatsuchi S, Hiraiwa Y, Murakami J, Kato T, Takahara T and Watanabe A: Thrombotic thrombocytopenia purpura caused by piperacillin successfully treated with plasma infusion Ann Hematol 2000, 79:593-595.
18. Perez-Vazquez A, Pastor JM and Riancho JA: Immune thrombocytopenia caused by piperacillin/tazobactam Clin Infect Dis 1998, 27:650-651.