Hepatitis B virus-infected peripheral blood progenitor cell harvests in liquid nitrogen freezer containing non-infectious products [1]

Transfusion

Volumn 44, Issue 6, 2004, Pages 942-943

  Husebekk, Anne ^a   Skaug, Kjell ^b   Kolstad, Arne ^a   Dahl, Inger Marie S ^a   Gutteberg, Tore ^a   Skogen, Bjørn ^a  

^a UNIVERSITY HOSPITAL OF NORTH NORWAY   (Norway)

^b NORWEGIAN INSTITUTE OF PUBLIC HEALTH   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

LIQUID NITROGEN;

CASE REPORT; CRYOPRESERVATION; HEPATITIS B; HEPATITIS B VIRUS; HUMAN; INFECTION RISK; LETTER; PERIPHERAL BLOOD STEM CELL; PERIPHERAL BLOOD STEM CELL TRANSPLANTATION; VIRAL CONTAMINATION;

BLOOD PRESERVATION; CRYOPRESERVATION; DISEASE TRANSMISSION, HORIZONTAL; DISINFECTION; EQUIPMENT CONTAMINATION; EQUIPMENT FAILURE; HEMATOPOIETIC STEM CELLS; HEPATITIS B; HEPATITIS B SURFACE ANTIGENS; HEPATITIS B VIRUS; HUMANS; MULTIPLE MYELOMA; PERIPHERAL BLOOD STEM CELL TRANSPLANTATION; RNA, VIRAL; VIREMIA;

EID: 2942596132     PISSN: 00411132     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1537-2995.2004.00379.x     Document Type: Letter

References (5)

1. Tedder RS, Zuckerman MA, Goldstone AH, et al. Hepatitis B transmission from contaminated cryopreservation tank. Lancet 1995;346:137-40.
2. Fountain D, Ralston M, Higgins N, et al. Liquid nitrogen freezers: a potential source of microbial contamination of hematopoietic stem cell products. Transfusion 1997;37:585-91.
3. Omata M, Ehata T, Yokosuka O, et al. Mutations in the precore region of hepatitis B virus DNA in patients with fulminant and severe hepatitis. N Engl J Med 1991;324:1699-704.
4. Okamoto H, Yotsumoto S, Akahane Y, et al. Hepatitis B viruses with precore region defects prevail in persistently infected hosts along with seroconversion to the antibody against the antigen. J Virol 1990;64:1298-303.
5. Khuu HM, Cowley H, David-Ocambo V, et al. Catastrophic failures of freezing bags for cellular therapy products: description, cause, and consequences. Cytotherapy 2002;4:539-49.