The Rapamycin derivative RAD inhibits mesangial cell migration through the CDK-inhibitor p27KIP1

Laboratory Investigation

Volumn 84, Issue 5, 2004, Pages 588-596

  Daniel, Christoph ^a   Pippin, Jeffrey ^b   Shankland, Stuart J ^b   Hugo, Christian ^a  

^a UNIVERSITY HOSPITAL ERLANGEN   (Germany)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

Anti Thy1 model; CDK inhibitors; Glomerular migration; Glomerular repopulation; RAD

Indexed keywords

BROXURIDINE; CYCLIN DEPENDENT KINASE INHIBITOR; EVEROLIMUS; FIBRONECTIN; PROTEIN P21; PROTEIN P27; RAPAMYCIN DERIVATIVE; S6 KINASE; CDKN1A PROTEIN, MOUSE; CDKN1A PROTEIN, RAT; CDKN1B PROTEIN, MOUSE; CDKN1B PROTEIN, RAT; CELL CYCLE PROTEIN; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE INHIBITOR 1A; CYCLIN DEPENDENT KINASE INHIBITOR 1B; CYCLINE; MACROLIDE; RAD MACROLIDE; TUMOR SUPPRESSOR PROTEIN;

ANIMAL CELL; ARTICLE; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL MIGRATION; CHEMOTAXIS; CONTROLLED STUDY; DOSE RESPONSE; ENZYME PHOSPHORYLATION; IMMUNOHISTOCHEMISTRY; MESANGIUM CELL; MORPHOMETRICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROLIFERATIVE GLOMERULONEPHRITIS; TISSUE REPAIR; WESTERN BLOTTING; WILD TYPE; ANIMAL; CELL CULTURE; CELL MOTION; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; IN VITRO STUDY; MALE; MESANGIUM; METABOLISM; MOUSE MUTANT; NEPHRITIS; PATHOLOGY; PHOSPHORYLATION; RAT; SPRAGUE DAWLEY RAT;

ANIMALS; CELL CYCLE PROTEINS; CELL MOVEMENT; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLIN-DEPENDENT KINASE INHIBITOR P27; CYCLIN-DEPENDENT KINASES; CYCLINS; FIBRONECTINS; GLOMERULAR MESANGIUM; MACROLIDES; MALE; MICE; MICE, KNOCKOUT; NEPHRITIS; PHOSPHORYLATION; RATS; RATS, SPRAGUE-DAWLEY; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; TUMOR SUPPRESSOR PROTEINS;

EID: 2942594770     PISSN: 00236837     EISSN: None     Source Type: Journal    
DOI: 10.1038/labinvest.3700078     Document Type: Article

References (26)

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