Absence of NR4A2 exon 1 mutations in 108 families with autosomal dominant Parkinson disease

Neurology

Volumn 62, Issue 11, 2004, Pages 2133-2134

  Ibanez P ^a   Lohmann, E ^a   Pollak, P ^b   Durif, F ^c   Tranchant, C ^d   Agid, Y ^a   Durr A ^a   Brice, Alexis ^a  

^a PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^b GRENOBLE UNIVERSITY HOSPITAL   (France)

^c SERVICE DE RHUMATOLOGIE   (France)

^d HÔPITAL CIVIL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

GENOMIC DNA; PRIMER DNA;

ADULT; AGED; ARTICLE; AUTOSOMAL DOMINANT DISORDER; BRADYKINESIA; DNA SEQUENCE; EXON; FEMALE; GENE; GENE AMPLIFICATION; GENE FUNCTION; GENE MUTATION; GENETIC POLYMORPHISM; HETEROZYGOSITY; HUMAN; MAJOR CLINICAL STUDY; MALE; MUSCLE RIGIDITY; NR4A2 GENE; PARKINSON DISEASE; PRIORITY JOURNAL; SEQUENCE ANALYSIS; TREMOR;

EID: 2942594470     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/01.WNL.0000127496.23198.75     Document Type: Article

References (7)

1. Le WD, Xu P, Jankovic J, et al. Mutations in NR4A2 associated with familial Parkinson disease. Nat Genet 2003;33:85-89.
2. Wellenbrock C, Hedrich K, Schafer N, et al. NR4A2 mutations are rare among European patients with familial Parkinson's disease. Ann Neurol 2003;54:415.
3. Zimprich A, Asmus F, Leitner P, et al. Point mutations in exon 1 of the NR4A2 gene are not a major cause of familial Parkinson's disease. Neurogenetics 2003;4:219-220.
4. Xu PY, Liang R, Jankovic J, et al. Association of homozygous 7048G7049 variant in the intron six of Nurrl gene with Parkinson's disease. Neurology 2002;58:881-884.
5. Zheng K, Heydari B, Simon DK. A common NURR1 polymorphism associated with Parkinson disease and diffuse Lewy body disease. Arch Neurol 2003;60:722-725.
6. Carmine A, Buervenich S, Galter D, et al. NURR1 promoter polymorphisms: Parkinson's disease, schizophrenia, and personality traits. Am J Med Genet 2003;120B:51-57.
7. Tan EK, Chung H, Zhao Y, et al. Genetic analysis of Nurr1 haplotypes in Parkinson's disease. Neurosci Lett 2003;347:139-142.