메뉴 건너뛰기




Volumn 26, Issue 6, 2004, Pages 247-254

Functional analysis of the interleukin-5 receptor antagonist peptide, AF18748

Author keywords

Chain; Cytokines; Eosinophils; IL 5; Signaling pathways

Indexed keywords

AF 18748; INTERLEUKIN 5; INTERLEUKIN 5 RECEPTOR ANTAGONIST; PEPTIDE; UNCLASSIFIED DRUG;

EID: 2942588801     PISSN: 10434666     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cyto.2003.10.012     Document Type: Article
Times cited : (4)

References (27)
  • 1
    • 0025008579 scopus 로고
    • The eosinophil and bronchial asthma: Current understanding
    • Gleich G.J. The eosinophil and bronchial asthma: current understanding. J Allergy Clin Immunol. 85:1990;422-436
    • (1990) J Allergy Clin Immunol , vol.85 , pp. 422-436
    • Gleich, G.J.1
  • 2
    • 0034049677 scopus 로고    scopus 로고
    • Mechanisms of eosinophils-associated inflammation
    • Gleich G.J. Mechanisms of eosinophils-associated inflammation. J Allergy Clin Immunol. 105:(4):2000;651-663
    • (2000) J Allergy Clin Immunol , vol.105 , Issue.4 , pp. 651-663
    • Gleich, G.J.1
  • 3
    • 0032885128 scopus 로고    scopus 로고
    • Interleukin-5 and the regulation of eosinophil production
    • Roboz G.J., Rafii S. Interleukin-5 and the regulation of eosinophil production. Curr Opin Hematol. 6:(3):1999;164-168
    • (1999) Curr Opin Hematol , vol.6 , Issue.3 , pp. 164-168
    • Roboz, G.J.1    Rafii, S.2
  • 4
    • 0034004421 scopus 로고    scopus 로고
    • IL-5: Biology and potential therapeutic applications
    • Weltman J.K., Karim A.S. IL-5: biology and potential therapeutic applications. Expert Opin Investig Drugs. 9:(3):2000;491-496
    • (2000) Expert Opin Investig Drugs , vol.9 , Issue.3 , pp. 491-496
    • Weltman, J.K.1    Karim, A.S.2
  • 6
    • 0029065957 scopus 로고
    • Interleukin-5 and its receptor: A drug target for eosinophilia associated with chronic allergic disease
    • Devos R., Plaetinck G., Cornelis S., Guisez Y., Van der Heyden J., Tavernier J. Interleukin-5 and its receptor: a drug target for eosinophilia associated with chronic allergic disease. J Leukoc Biol. 57:1995;813-819
    • (1995) J Leukoc Biol , vol.57 , pp. 813-819
    • Devos, R.1    Plaetinck, G.2    Cornelis, S.3    Guisez, Y.4    Van Der Heyden, J.5    Tavernier, J.6
  • 7
    • 0034536831 scopus 로고    scopus 로고
    • Interleukin-5: A drug target for allergic diseases
    • Sanderson C.J., Urwin D. Interleukin-5: a drug target for allergic diseases. Curr Opin Investig Drugs. 1:2000;435-441
    • (2000) Curr Opin Investig Drugs , vol.1 , pp. 435-441
    • Sanderson, C.J.1    Urwin, D.2
  • 8
    • 0035993364 scopus 로고    scopus 로고
    • Development of IL-5 receptor antagonists
    • Uings I., Mckinnon M. Development of IL-5 receptor antagonists. Curr Pharm Des. 8:2002;1837-1844
    • (2002) Curr Pharm des , vol.8 , pp. 1837-1844
    • Uings, I.1    McKinnon, M.2
  • 9
    • 0025770219 scopus 로고
    • A human high affinity interleukin-5 receptor (IL5R) is composed of an IL5-specific alpha chain and a beta chain shared with the receptor for GM-CSF
    • Tavernier J., Devos R., Cornelis S., Tuypens T., Van der Heyden J., Fiers W., et al. A human high affinity interleukin-5 receptor (IL5R) is composed of an IL5-specific alpha chain and a beta chain shared with the receptor for GM-CSF. Cell. 66:(6):1995;1175-1184
    • (1995) Cell , vol.66 , Issue.6 , pp. 1175-1184
    • Tavernier, J.1    Devos, R.2    Cornelis, S.3    Tuypens, T.4    Van Der Heyden, J.5    Fiers, W.6
  • 10
    • 0034141996 scopus 로고    scopus 로고
    • Evidence for local eosinophil differentiation within allergic nasal mucosa: Inhibition with soluble receptor
    • Cameron L., Christodoulopoulos P., Lavigne F., Nakamura Y., Eidelman D., McEuen A., et al. Evidence for local eosinophil differentiation within allergic nasal mucosa: inhibition with soluble receptor. J Immunol. 164:2000;1539-1545
    • (2000) J Immunol , vol.164 , pp. 1539-1545
    • Cameron, L.1    Christodoulopoulos, P.2    Lavigne, F.3    Nakamura, Y.4    Eidelman, D.5    McEuen, A.6
  • 11
    • 0029000927 scopus 로고
    • Identification of receptor-binding domains on human interleukin-5 and design of an interleukin-5 derived receptor antagonist
    • Tavernier J., Tuypens T., Verhee A., Plaentinck G., Devos R., Van der Heyden J., et al. Identification of receptor-binding domains on human interleukin-5 and design of an interleukin-5 derived receptor antagonist. Proc Natl Acad Sci U S A. 92:1995;5194-5198
    • (1995) Proc Natl Acad Sci U S a , vol.92 , pp. 5194-5198
    • Tavernier, J.1    Tuypens, T.2    Verhee, A.3    Plaentinck, G.4    Devos, R.5    Van Der Heyden, J.6
  • 12
    • 0030789070 scopus 로고    scopus 로고
    • An interleukin 5 mutant distinguishes between two functional responses in human eosinophils
    • Mckinnon M., Page K., Uings I.J., Banks M., Fattah D., Proudfoot A.E.I., et al. An interleukin 5 mutant distinguishes between two functional responses in human eosinophils. J Exp Med. 186:1997;121-129
    • (1997) J Exp Med , vol.186 , pp. 121-129
    • McKinnon, M.1    Page, K.2    Uings, I.J.3    Banks, M.4    Fattah, D.5    Proudfoot, A.E.I.6
  • 13
    • 0033406772 scopus 로고    scopus 로고
    • Mapping and characterization of the epitope(s) of Sch 55700, a humanized mAb, that inhibits human IL-5
    • Zhang J., Kuvelkar R., Murgolo N., Taremi S., Chou C.C., Wang P., et al. Mapping and characterization of the epitope(s) of Sch 55700, a humanized mAb, that inhibits human IL-5. Int Immunol. 11:1999;1935-1943
    • (1999) Int Immunol , vol.11 , pp. 1935-1943
    • Zhang, J.1    Kuvelkar, R.2    Murgolo, N.3    Taremi, S.4    Chou, C.C.5    Wang, P.6
  • 14
  • 15
    • 0035838988 scopus 로고    scopus 로고
    • Cytokine-specific transcriptional regulation through an IL-5R alpha interacting protein
    • Geijsen N., Uings I.J., Pals C., Armstrong J., McKinnon M., Raaijmakers J.A., et al. Cytokine-specific transcriptional regulation through an IL-5R alpha interacting protein. Science. 293:2001;1136-1138
    • (2001) Science , vol.293 , pp. 1136-1138
    • Geijsen, N.1    Uings, I.J.2    Pals, C.3    Armstrong, J.4    McKinnon, M.5    Raaijmakers, J.A.6
  • 16
    • 0031036882 scopus 로고    scopus 로고
    • The structural and functional basis of cytokine receptor activation: Lessons from the common beta subunit of the granulocyte-macrophage colony-stimulating factor, interleukin-3 (IL-3), and IL-5 receptors
    • Bagley C.J., Woodcock J.M., Stomski F.C., Lopez A.F. The structural and functional basis of cytokine receptor activation: lessons from the common beta subunit of the granulocyte-macrophage colony-stimulating factor, interleukin-3 (IL-3), and IL-5 receptors. Blood. 89:(5):1997;1471-1482
    • (1997) Blood , vol.89 , Issue.5 , pp. 1471-1482
    • Bagley, C.J.1    Woodcock, J.M.2    Stomski, F.C.3    Lopez, A.F.4
  • 17
    • 0031671711 scopus 로고    scopus 로고
    • The mechanism of IL-5 signal transduction
    • Adachi T., Alam R. The mechanism of IL-5 signal transduction. Am J Physiol. 275:(3):1998;C623-C633
    • (1998) Am J Physiol , vol.275 , Issue.3 , pp. 623-C633
    • Adachi, T.1    Alam, R.2
  • 19
    • 0034655647 scopus 로고    scopus 로고
    • Structure of the activation domain of GM-CSF/IL-3/IL-5 receptor common β-chain bound to an antagonist
    • Rossjohn J., Mckintry W.J., Woodcock J.M., McClure B.J., Hercus T.R., Parker M.W., et al. Structure of the activation domain of GM-CSF/IL-3/IL-5 receptor common β-chain bound to an antagonist. Blood. 95:2000;2491-2497
    • (2000) Blood , vol.95 , pp. 2491-2497
    • Rossjohn, J.1    McKintry, W.J.2    Woodcock, J.M.3    McClure, B.J.4    Hercus, T.R.5    Parker, M.W.6
  • 20
    • 17744386517 scopus 로고    scopus 로고
    • Structure of the complete extracellular domain of the common β subunit of the human GM-CSF, IL-3 and IL-5 receptors reveals a novel dimer configuration
    • Carr P.D., Gustin S.E., Church A.P., Murphy J.M., Ford S.C., Mann D.A., et al. Structure of the complete extracellular domain of the common β subunit of the human GM-CSF, IL-3 and IL-5 receptors reveals a novel dimer configuration. Cell. 104:2001;291-300
    • (2001) Cell , vol.104 , pp. 291-300
    • Carr, P.D.1    Gustin, S.E.2    Church, A.P.3    Murphy, J.M.4    Ford, S.C.5    Mann, D.A.6
  • 21
    • 0028981023 scopus 로고
    • Detailed analysis of the IL-5-IL5Rα interaction: Characterization of crucial residues on the ligand and the receptor
    • Cornelis S., Geert P., Devos R., Van der Heyden J., Tavernier J., Sanderson C., et al. Detailed analysis of the IL-5-IL5Rα interaction: characterization of crucial residues on the ligand and the receptor. EMBO J. 14:(14):1995;3395-3402
    • (1995) EMBO J , vol.14 , Issue.14 , pp. 3395-3402
    • Cornelis, S.1    Geert, P.2    Devos, R.3    Van Der Heyden, J.4    Tavernier, J.5    Sanderson, C.6
  • 22
    • 0035822269 scopus 로고    scopus 로고
    • Modified peptide antagonists of interleukin 5 exhibit extended in vivo persistence but restricted species specificity
    • Uings I.J., Balasubramanian P., McLoughlin P.G., Yin Q., Dash L., Beresford A., et al. Modified peptide antagonists of interleukin 5 exhibit extended in vivo persistence but restricted species specificity. Cytokine. 15:(1):2001;10-19
    • (2001) Cytokine , vol.15 , Issue.1 , pp. 10-19
    • Uings, I.J.1    Balasubramanian, P.2    McLoughlin, P.G.3    Yin, Q.4    Dash, L.5    Beresford, A.6
  • 23
    • 0023812908 scopus 로고
    • An improved method for the isolation of eosinophilic granulocytes from peripheral blood of normal individuals
    • Koenderman L., Kok P.T., Hamelink M.L., Verhoeven A.J., Bruijnzeel P. An improved method for the isolation of eosinophilic granulocytes from peripheral blood of normal individuals. J Leuk Biol. 44:(2):1988;79-86
    • (1988) J Leuk Biol , vol.44 , Issue.2 , pp. 79-86
    • Koenderman, L.1    Kok, P.T.2    Hamelink, M.L.3    Verhoeven, A.J.4    Bruijnzeel, P.5
  • 24
    • 0028834634 scopus 로고
    • Activation of the STAT3/acute phase response factor transcription factor by interleukin-5
    • Oct 27
    • Caldenhoven E., van Dijk T., Raaijmakers J.A., Lammers J.W., Koenderman L., De Groot R.P. Activation of the STAT3/acute phase response factor transcription factor by interleukin-5. J Biol Chem. 270:(43):Oct 27 1995;25778-25784
    • (1995) J Biol Chem , vol.270 , Issue.43 , pp. 25778-25784
    • Caldenhoven, E.1    Van Dijk, T.2    Raaijmakers, J.A.3    Lammers, J.W.4    Koenderman, L.5    De Groot, R.P.6
  • 25
    • 0029924353 scopus 로고    scopus 로고
    • A rapid activation assay for human eosinophils based on adhesion to immobilized ICAM-1, VCAM-1 and IgG
    • Fattah D., Page K.R., Bezbaruah S., Priest R.C., Horgan C.M., Solari R. A rapid activation assay for human eosinophils based on adhesion to immobilized ICAM-1, VCAM-1 and IgG. Cytokine. 8:(3):1996;248-259
    • (1996) Cytokine , vol.8 , Issue.3 , pp. 248-259
    • Fattah, D.1    Page, K.R.2    Bezbaruah, S.3    Priest, R.C.4    Horgan, C.M.5    Solari, R.6
  • 26
    • 0030010209 scopus 로고    scopus 로고
    • Mechanisms involved in eosinophil migration. Platelet-activating factor-induced chemotaxis and interleukin-5-induced chemokinesis are mediated by different signals
    • Schweizer R.C., van Kessel-Welmers B.A., Warringa R.A., Maikoe T., Raaijmakers J.A., Lammers J.W., et al. Mechanisms involved in eosinophil migration. Platelet-activating factor-induced chemotaxis and interleukin-5-induced chemokinesis are mediated by different signals. J Leukoc Biol. 59:(3):1996;347-356
    • (1996) J Leukoc Biol , vol.59 , Issue.3 , pp. 347-356
    • Schweizer, R.C.1    Van Kessel-Welmers, B.A.2    Warringa, R.A.3    Maikoe, T.4    Raaijmakers, J.A.5    Lammers, J.W.6
  • 27
    • 0016375453 scopus 로고
    • Oxygen consumption of phagocytizing cells in human leukocyte and granulocyte preparations: A comparative study
    • Weening R.S., Roos D., Loos J.A. Oxygen consumption of phagocytizing cells in human leukocyte and granulocyte preparations: a comparative study. J Lab Clin Med. 83:1974;570-577
    • (1974) J Lab Clin Med , vol.83 , pp. 570-577
    • Weening, R.S.1    Roos, D.2    Loos, J.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.