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Bioorganic and Medicinal Chemistry Letters

Volumn 14, Issue 14, 2004, Pages 3651-3654

(±)8-Amino-5,6,7,8-tetrahydroisoquinolines as novel antinociceptive agents

(7) Dukat, Małgorzata a Taroua, Mohamed a Dahdouh, Abdelaziz a Siripurapu, Umamaheswar a Damaj, M Imad a Martin, Billy R a Glennon, Richard A a

a VIRGINIA COMMONWEALTH UNIVERSITY (United States)

Author keywords

Aminoisoquinolines; Analgesia; Hot plate; Tail flick

Indexed keywords

8 AMINO 5,6,7,8 TETRAHYDROISOQUINOLINE DERIVATIVE; ANTINOCICEPTIVE AGENT; NICOTINE; NICOTINIC RECEPTOR; PYRIDINE DERIVATIVE; TETRAHYDROISOQUINOLINE DERIVATIVE; UNCLASSIFIED DRUG; ANALGESIC AGENT; LIGAND;

ANIMAL EXPERIMENT; ANTINOCICEPTION; ARTICLE; CONFORMATION; MOUSE; NONHUMAN; RECEPTOR BINDING; SUBSTITUTION REACTION; ANIMAL; CELL CULTURE; DISEASE MODEL; DRUG EFFECT; METABOLISM; PAIN; SYNTHESIS;

RODENTIA;

ANALGESICS; ANIMALS; CELLS, CULTURED; DISEASE MODELS, ANIMAL; LIGANDS; MICE; PAIN; RECEPTORS, NICOTINIC; TETRAHYDROISOQUINOLINES;

EID: 2942587158 PISSN: 0960894X EISSN: None Source Type: Journal
DOI: 10.1016/j.bmcl.2004.05.020 Document Type: Article

Times cited : (7)

References (9)

1
- 2942607101
- Glennon R.A., Dukat M., Liao L. Curr. Top. Med. Chem. 4:2004;631-644
- (2004) Curr. Top. Med. Chem. , vol.4 , pp. 631-644
- Glennon, R.A.¹ Dukat, M.² Liao, L.³

2
- 2942578767
- Glennon R.A. Prog. Med. Chem. 42:2004;55-123
- (2004) Prog. Med. Chem. , vol.42 , pp. 55-123
- Glennon, R.A.¹

3
- 0029801534
- Glennon R.A., Fiedler W., Dukat M., Damaj I., Martin B. Eur. J. Med. Chem. 31:1996;875-888
- (1996) Eur. J. Med. Chem. , vol.31 , pp. 875-888
- Glennon, R.A.¹ Fiedler, W.² Dukat, M.³ Damaj, I.⁴ Martin, B.⁵

4
- 0032719341
- Cheng Y.-X., Dukat M., Dowd M., Fiedler W., Martin B., Damaj M.I., Glennon R.A. Eur. J. Med. Chem. 34:1999;177-190
- (1999) Eur. J. Med. Chem. , vol.34 , pp. 177-190
- Cheng, Y.-X.¹ Dukat, M.² Dowd, M.³ Fiedler, W.⁴ Martin, B.⁵ Damaj, M.I.⁶ Glennon, R.A.⁷

5
- 0037194644
- Ullrich T., Krich S., Binder D., Mereiter K., Anderson D.J., Meyer M.D., Pyerin M.J. J. Med. Chem. 45:2002;4047-4054
- (2002) J. Med. Chem. , vol.45 , pp. 4047-4054
- Ullrich, T.¹ Krich, S.² Binder, D.³ Mereiter, K.⁴ Anderson, D.J.⁵ Meyer, M.D.⁶ Pyerin, M.J.⁷

6
- 0027361359
- Glassco W., Suchocki J., George C., Martin B.R., May E.L. J. Med. Chem. 36:1993;3381-3385
- (1993) J. Med. Chem. , vol.36 , pp. 3381-3385
- Glassco, W.¹ Suchocki, J.² George, C.³ Martin, B.R.⁴ May, E.L.⁵

7
- 0032544153
- Vernier J.-M., Holsenback H., Cosford N.D.P., Whitten J.P., Menzaghi F., Reid R., Rao T.S., Sacaan A.I., Lloyd K., Suto C.M., Chavez-Noriega L.E., Washburn M.S., Urrutia A., McDonald I.A. Bioorg. Med. Chem. Lett. 8:1998;2173-2178
- (1998) Bioorg. Med. Chem. Lett. , vol.8 , pp. 2173-2178
- Vernier, J.-M.¹ Holsenback, H.² Cosford, N.D.P.³ Whitten, J.P.⁴ Menzaghi, F.⁵ Reid, R.⁶ Rao, T.S.⁷ Sacaan, A.I.⁸ Lloyd, K.⁹ Suto, C.M.¹⁰ Chavez-Noriega, L.E.¹¹ Washburn, M.S.¹² Urrutia, A.¹³ McDonald, I.A.¹⁴

8
- 0037169247
- i values (at least in triplicate). The tail-flick assay employed male ICR mice (20-25 g; Harlan Laboratories, Indianapolis, IN) that were housed in an AALAC approved facility in groups of six and had free access to food and water. The study was approved by the Institutional Animal Care and Use Committee of VCU.
- 9 using a 30-gauge needle attached to a glass microsyringe. The injection volume in all cases was 5 μL. In the hot-plate test, mice were placed into a 10 cm wide glass cylinder on a hot plate (Thermojust Apparatus) maintained at 55°C, and the antinociceptive response was calculated as %MPE. Groups of 6-12 mice were used for each dose, and mice were tested 5 min after subcutaneous injections
- (2002) Eur. J. Pharmacol. , vol.435 , pp. 171-180
- Dukat, M.¹ Damaj, I.M.² Young, R.³ Vann, R.⁴ Collins, A.C.⁵ Marks, M.J.⁶ Martin, B.R.⁷ Glennon, R.A.⁸

9
- 0018956018
- Hyldon J.L., Wilcox G.L. Eur. J. Pharmacol. 67:1980;313
- (1980) Eur. J. Pharmacol. , vol.67 , pp. 313
- Hyldon, J.L.¹ Wilcox, G.L.²

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.