Porcine FAD-containing monooxygenase metabolizes lidocaine, bupivacaine and propranolol in vitro

Life Sciences

Volumn 75, Issue 8, 2004, Pages 1011-1019

  Wu, Ru Feng ^a   Liao, Cheng Xu ^a   Tomita, Shuhei ^b   Ichikawa, Yoshiyuki ^b   Terada, Lance S ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b KAGAWA UNIVERSITY   (Japan)

Author keywords

adrenergic blocking reagent; Bupivacaine; FAD containing monooxygenase; Lidocaine; Propranolol

Indexed keywords

BUPIVACAINE; DIMETHYLANILINE MONOOXYGENASE; HYDROXYLAMINE; LIDOCAINE; LOCAL ANESTHETIC AGENT; OXIDE; PROPRANOLOL;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG METABOLISM; FEMALE; GAS CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; LIPOPHILICITY; MASS SPECTROMETRY; NONHUMAN; PHASE SEPARATION;

ANIMALS; BUPIVACAINE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FEMALE; LIDOCAINE; MICROSOMES, LIVER; OXYGENASES; PROPRANOLOL; SOLUBILITY; SWINE;

SUIDAE;

EID: 2942585606     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2004.02.018     Document Type: Article

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