Changes in body temperature and sleep-wakefulness after intrapreoptic injection of methoxamine in rats

Neural Plasticity

Volumn 10, Issue 4, 2003, Pages 267-278

  Vetrivelan, Ra ^a   Mallick, Hruda Nanda ^a   Kumar, Velayudhan Mohan ^a  

^a ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

Dose response; Hypothermia; Medial preoptic area; Norepinephrine; Telemetry

Indexed keywords

METHOXAMINE; ALPHA 1 ADRENERGIC RECEPTOR; ALPHA ADRENERGIC RECEPTOR STIMULATING AGENT;

ANIMAL TISSUE; ARTICLE; BODY TEMPERATURE; CEREBROSPINAL FLUID; CONTROLLED STUDY; DRUG DOSE REGIMEN; ELECTROENCEPHALOGRAPHY; ELECTROMYOGRAPHY; ELECTROOCULOGRAPHY; MALE; NONHUMAN; RANK SUM TEST; RAT; REM SLEEP; SLEEP WAKING CYCLE; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; TELEMETRY; THERMOREGULATION; WAKEFULNESS; ANIMAL; AROUSAL; DOSE RESPONSE; DRUG EFFECT; MICROINJECTION; PHYSIOLOGY; PREOPTIC AREA; SLEEP; WISTAR RAT;

ADRENERGIC ALPHA-AGONISTS; ANIMALS; AROUSAL; BODY TEMPERATURE; DOSE-RESPONSE RELATIONSHIP, DRUG; MALE; METHOXAMINE; MICROINJECTIONS; PREOPTIC AREA; RATS; RATS, WISTAR; RECEPTORS, ADRENERGIC, ALPHA-1; SLEEP; TELEMETRY; WAKEFULNESS;

EID: 2942585604     PISSN: 20905904     EISSN: None     Source Type: Journal    
DOI: 10.1155/NP.2003.267     Document Type: Article

References (55)

1. Anden NE, Dahlstrom A, Fuxe K, Olson L, Ungerstedt U. 1966. Ascending noradrenaline neurons from the pons and the medulla oblongata. Experientia 22: 44-45.
2. Andersson B, Gale CC, Hokfelt B, Larsson B. 1965. Acute and chronic effects of preoptic lesions. Acta Physiol Scand 65: 45-60.
3. Asala SA, Okano Y, Hondo K, Inoue S. 1990. Effects of medial preoptic area lesion on sleep and wakefulness in unrestrained rats. Neurosci Lett 114: 300-304.
4. Bagga N, Chhina GS, Kumar VM, Singh B. 1981. Mechanism of participation of medial preoptic area in the hippocampal inhibition of ovulation. Brain Res 216: 444-448.
5. Blechova R, Pivodova D. 2001. Limulus amoebocyte lysate (LAL) test - an alternative method for detection of bacterial endotoxins. Acta Vet Brno 70: 291-296.
6. Boulant JA. 1980. Hypothalamic control of thermoregulation: Neurophysiological Basis. In: Morgane PJ, Panksepp J, eds, Handbook of Hypothalamus, Vol. 3. New York, NY, USA: Marcel Dekker Inc; 1-82.
7. Datta S, Kumar VM, Chhina GS, Singh B. 1987. Effect of application of serotonin in medial preoptic area on body temperature and sleep-wakefulness. Ind J Exp Biol 25:681-685.
8. Datta S, Kumar VM, Chhina GS, Singh B. 1988. Interrelationship of thermal and sleep-wakefulness changes elicited from the medial preoptic area in rats. Exp Neurol 100: 40-50.
9. Datta S, Mohan Kumar V, Chhina GS, Singh B. 1985. Tonic activity of medial preoptic norepinephrine mechanism for body temperature maintenance in sleeping and awake rats. Brain Res Bull 15: 447-451.
10. De Groot J. 1959. The rat forebrain in stereotaxic coordinates. Trans R Neth Acad Sci 52: 1-40.
11. Feldberg W, Myers RD. 1965. Changes in temperature produced by micro-injections of amines into the anterior hypothalamus of cats. J Physiol 177: 239-245.
12. Hayashi O. 1988. Sleep-wake regulation by prostaglandins D2 and E2. J Biol Chem 263: 14593-96.
13. Hernendez-Peon R, Chavez-Ibarra CG. 1963. Sleep induced by electrical or chemical stimulation of the forebrain. Electroenceph Clin Neurophysiol 24: 188-198.
14. Hori T, Kiyohara T, Nakashima T, Shibata M. 1982. Responses of preoptic thermosenstitive neurons to medial forebrain bundle stimulation. Brain Res Bull 8: 667-675.
15. Hori T, Nakayama T. 1973. Effects of biogenic amines on central thermoresponsive neurons in the rabbit. J Physiol 232: 71-85.
16. John J, Kumar VM, Gopinath G, Ramesh V, Mallick HN. 1994. Changes in sleep-wakefulness after kainic acid lesion of the preoptic area in rats. Jap J Physiol 41: 1-22.
17. John J, Kumar VM. 1998. Effect of NMDA lesion of the medial preoptic neurons on sleep and other functions. Sleep 21: 585-595.
18. Kent S, Satinoff E. 1990. Influence of ambient temperature on sleep and body temperature after phentolamine in rats. Brain Res 511: 227-233.
19. Krueger JM, Takahashi S. 1997. Thermoregulation and sleep: closely linked but separable. Ann NY Acad Sci 813: 281-286.
20. Kumar VM, Khan NA. 1998. Role of the preoptic neurons in thermoregulation in rats. Arch Clin Exp Med 7: 24-27.
21. Kumar VM, Sharma R, Wadhwa S, Manchanda SK. 1993. Sleep inducing function of the noradrenergic fibres in the medial preoptic area. Brain Res Bull 32: 153-158.
22. Kumar VM. 2003a. Interrelation between thermoregulation and sleep regulation. Proc Indian Natl Sci Acad B69: 418-435.
23. Kumar VM. 2003b. Role of noradrenergic fibers of the preoptic area in regulating sleep. J Chem Neuroanat 26: 87-93.
24. Kumar VM. 1999. Role of preoptic area in the interrelationship between thermoregulatory and sleep regulatory mechanisms. Sleep Hypn 1: 1-9.
25. Langer SZ. 1974. Presynaptic regulation of catecholamine release. Biochem Pharmacol 23: 1793-1800.
26. Magoun HW, Harrison F, Brobeck JR, Ranson SW. 1938. Activation of heat loss mechanisms by local heating of the brain. J Neurophysiol 1: 101-114.
27. Mallick BN, Alam MN. 1992. Different types of norepinephrine receptors are involved in preoptic area rhediated independent modulation of sleep-wakefulness and body temperature. Brain Res 591: 8-19.
28. Mallick HN, Mohan Kumar V, Singh B. 1988. Thermal changes produced by norepinephrine application in the preoptic area of monkeys. Ind J Physiol Pharmacol 32: 265-270.
29. McGinty D, Sterman MB. 1968. Sleep suppression after basal forebrain lesions in the cat. Science 160: 1253-1255.
30. Mohan Kumar V, Datta S, Chhina GS, Gandhi N, Singh B. 1984. Sleep-wake responses elicited from the medial preoptic area on application of norepinephrine and phenoxybenzamine in free moving rats. Brain Res 322: 322-325.
31. 2 receptors in hypothalamus of cat. Pharmacol Biochem Behav 26: 373-379.
32. Nauta WJH. 1946. Hypothalamic regulation of sleep in rats: An experimental study. J Neurophysiol 9: 285-316.
33. Nicholas AP, Peiribone VA, Hokfelt T. 1993. Cellular localization of messenger RNA for beta-1 and beta-2 adrenergic receptors in rat brain: an in situ hybridization study. Neuroscience 56: 1023-1039.
34. 2 receptors in the rat. Neurosci Res 21: 323-330.
35. Osaka T, Matsumura H. 1994. Noradrenergic inputs to sleep-related neurons in the preoptic area from the locus coeruleus and ventrolateral medulla in the rat. Neurosci Res 19: 39-50.
36. Palacios JM, Wamsley JK. 1983. Microscopic localization of adrenoceptors. In: G.Kunos, ed, Adrenoceptors and Chatecholamine Action. Part B, New York, NY, USA: John Wiley; 295-313.
37. Palkovits M, Brownstein M, Saavendra JM, Axelrod J. 1974. Norepinephrine and dopamine content of hypothalamic nuclei of the rat. Brain Res 77: 137-149.
38. Panskepp J, Jalowiec JE, Morgane PJ, Zolovick AJ, Stern WC. 1973. Noradrenergic pathways and sleep-waking states in cats. Exp Neurol 41: 233-245.
39. Poole S, Stephenson JD. 1979. Effects of noradrenaline and carbachol on temperature regulation of rats. Br J Pharmacol 65: 43-51.
40. Quan N, Van Huysse J, Howell RD, Ungar A, Blatteis CM. 1988. Hyperthermia evoked by intrapreoptic administration of pyrogen-free saline (PFS): abolition by microdialysis. FASEB J 2: A1531.
41. Quan N, Xin L, Ungar AL, Blatteis CM. 1992. Preoptic norepinephrine-induced hypothermia is mediated by alpha-2 adrenoceptors. Am J Physiol 262: R407-R411.
42. Ramesh V, Kumar VM. 1998. The role of alpha-2 receptors in the medial preoptic area in the regulation of sleep-wakefulness and body temperature. Neuroscience 85: 807-817.
43. Ramesh V, Kumar VM, John J Mallick HN. 1995. Medial preoptic alpha-2 receptors in the regulation of sleep-wakefulness. Physiol Behav 57: 171-175.
44. Ramesh V, Kumar VM. 2000. Changes in sleep-wakefulness after 6-hydroxy dopamine lesion of the preoptic area. Neuroscience 98: 549-553.
45. Romanovsky AA, Shido O, Ungar AL, Blatteis CM. 1993. Genesis of biphasic thermal response to intrapreoptically mincroinjected clonidine. Brain Res Bull 31: 509-513.
46. Rudy TA, Williams JA, Yaksh TL. 1977. Antagonism by indomethacin of neurogenic hyperthermia produced by unilateral puncture of the anterior hypothalamic/preoptic region. J Physiol (Lond) 272: 721-736.
47. Rudy TA, Wolf HH. 1971. The effect of intrahypothalamically injected sympathomimetic amines on temperature regulation in the cat. J Pharmacol Exp Ther 179: 218-235.
48. 2 adrenergic receptor subtype gene expression in rat brain. Mol Brain Res 21: 133-149.
49. Sun JR, Ma YC, Xu ZH, Zhao WJ, Cai YP. 1997. Effect of norepinephrine on the thermosensitive neurons in the preoptic area of hypothalamus tissue slices in cold acclimatized rats. J Physiol 49: 666-670.
50. Swanson LW, Hartman BK. 1975. The central adrenergic system: An immunofluorescence study of the location of cell bodies and their efferent connections in the rat utilizing dopamine-β-hydroxylase as a marker. J Comp Neurol 163: 467-506.
51. Ticho SR, Radulovacki M. 1991. Role of adenosine in sleep and temperature regulation in the preoptic area of rats. Pharmacol Biochem Behav 40: 33-40.
52. 2 agonist binding sites in the rat and human central nervous system; analysis of some functional, anatomic correlates of the pharmacologic effects of clonidine and related adrenergic agents. Brain Res Rev 7: 69-101.
53. Walter JS, Meyers P, Krueger JM. 1989. Microinjection of interleukin-1 into brain: separation of sleep and fever responses. Physiol Behav 45: 169-176.
54. Woodroofe MN, Sarna GS, Wadhwa M, Hayes GM, Loughlin AJ, Tinker A, et al. 1991. Detection of interleukin-1 and interleukin-6 in adult rat brain, following mechanical injury, by in vivo microdialysis: evidence for a role for microglia in cytokine production. J Neuroimmunol 33: 227-236.
55. Zhang J, Ferenc Obal Jr, Zheng T, Fang J, Taishi P, Krueger JM. 1999. Intrapreoptic microinjection of GHRH or its antagonist alters sleep in rats. J Neurosci 19: 2187-2194.