Lack of effect of antineutrophil cytoplasmic antibodies associated with ulcerative colitis on superoxide anion production from neutrophils

Gut

Volumn 40, Issue 1, 1997, Pages 102-104

  Gionchetti, P ^a,d   Vecchi, M ^b   Rizzello, F ^a   Ferretti, M ^a   Calabresi, C ^b   Venturi, A ^a   Bianchi, M B ^b   Brignola, C ^a   Sinico, R A ^c   De Franchis, R ^b   Miglioli, M ^a   Campieri, M ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

^c SAN CARLO BORROMEO HOSPITAL   (Italy)

^d UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

Antineutrophil cytoplasmic antibodies; Respiratory burst; Superoxide anion; Ulcerative colitis

Indexed keywords

NEUTROPHIL CYTOPLASMIC ANTIBODY; OXYGEN RADICAL;

ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; NEUTROPHIL; PATHOGENESIS; PRIORITY JOURNAL; RESPIRATORY SYSTEM; ULCERATIVE COLITIS;

EID: 2942578786     PISSN: 00175749     EISSN: None     Source Type: Journal    
DOI: 10.1136/gut.40.1.102     Document Type: Article

References (24)

1. Davies DJ, Moran JE, Niall JF, Ryan GB. Segmental necrotizing glomerulonephritis with antineutrophil antibody: possible arbovirus aetiology? BMJ 1982; 258: 606.
2. Hall JB, Waldham B McN, Wood CJ, Ashton V, Adam WR. Vasculitis and glomerulonephritis: a subgroup with an antineutrophil cytoplasmic antibody. Aust N Z J Med 1984; 14: 277-8.
3. van der Woude FJ, Lobatto S, Permin H, van der Giessen M, Rasmussen N, Wiik A, et al. Autoantibodies against neutrophils and monocytes; tool for diagnosis and marker of disease activity in Wegener's granulomatosis. Lancet 1985; i: 425-9.
4. Falk RJ, Terrel RS, Charles LA, Jennette JC. Antineutrophil cytoplasmic autoantibodies induce neutrophils to degranulate and produce oxygen radicals in vitro. Proc Natl Acad Sci USA 1990; 87: 4115-9.
5. Charles LA, Caldas MLR, Falk RJ, Terrell RS, Jennette JC. Antibodies againist granule proteins activate neutrophils in vitro. Journal Leukoc Biol. 1991; 50: 539-46.
6. Ewert BH, Jennette JC, Falk RJ. Anti-myeloperoxidase antibodies stimulate neutrophils to damage human endothelial cells. Kidney Int 1992; 41: 375-83.
7. Savage COS, Pottinger BE, Gaskin U, Pusey CD, Pearson JD. Autoantibodies developing to myeloperoxidase and proteinase 3 in systemic vasculitis stimulate neutrophil cytotoxicity towards cultured endothelial cells. Am J Pathol 1992; 141: 335-42.
8. Hardarson S, La Brecque DR, Mitros FA, Neil GA, Goeken JA. Anti-neutrophil cytoplasmic antibody (ANCA) in inflammatory bowel and hepatobiliary diseases: high prevalence in ulcerative colitis, primary sclerosing cholangitis and autoimmune hepatitis. Am J Clin Pathol 1993; 99: 277-81.
9. Saxon A, Shanahan F, Landers C, Ganz T, Targan S. A distinct subset of antineutrophil cytoplasmic antibodies is associated with inflammatory bowel disease. J Allergy Clin Immunol 1990; 86: 202-10.
10. Rump JA, Scholmerich J, Gross V, Roth M, Helfesrieder R, Rautmann A, et al. A new type of perinuclear antineutrophil cytoplasmic antibody (p-ANCA) in active ulcerative colitis but not in Crohn's disease. Immunology 1990; 181: 406-13.
11. Jennette JC, Hogan S, Wilkman AS, Tuttle R, Jones D, Falk RJ. Anti-neutrophil cytoplasmic autoantibody disease associations. Am J Kidney Dis 1991; 18: 206-7.
12. Duerr RH, Targan SR, Landers CJ, Sutherland LR, Shanahan F. Antineutrophil cytoplasmic antibodies in ulcerative colitis. Gastroenterology 1991; 100: 1590-6.
13. Jennette JC, Falk RJ. Antineutrophil cytoplasmic autoantibodies in inflammatory bowel disease. Am J Clin Pathol 1993; 99: 221-3.
14. Gross WL, Schmitt WH, Csernok E. ANCA and associated diseases: immunodiagnostic and pathogenetic aspects. Clin Exp Immunol 1993; 91: 1-12.
15. Shanahan F. Neutrophil autoantibodies in inflammatory bowel disease: are they important? Gastroenterology 1994; 107: 586-9.
16. Bradford MA. A rapid and sensitive method of the quantitation of microgram of quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976; 72: 248-54.
17. Kallenberg CGM, Mulder AHL, Cohen Tervaert JW. Antineutrophil cytoplasmic antibodies: a still-growing class of autoantibodies in inflammatory disorders. Am J Med 1992; 92: 675-82.
18. Niles JL, McCluskey RT, Ahmad MF, Amaout MA. Wegener's granulomatosis autoantigen is a novel neutrophil serine proteinase. Blood 1989; 74: 1888-93.
19. Lüdemann J, Utecht B, Gross WL. Anti-neutrophil cytoplasmic antibodies in Wegener's granulomatosis recognize an elastinolytic enzyme. J Exp Med 1990; 171: 357-62.
20. Falk RJ, Jennette JC. Anti-neutrophil cytoplasmic autoantibodies with specificity for myeloperoxidase in patients with systemic vasculitis and idiopathic necrotizing and crescentic glomerulonephritis. N Engl J Med 1988; 318: 1651-7.
21. Duerr RH, Targan SR, Landers CJ, La Russo NF, Linsday KL, Wiesner RH, Shanahan F. Neutrophil cytoplasmic autoantibodies: a link between primary sclerosing cholangitis and ulcerative colitis. Gastroenterology 1991; 100: 1385-91.
22. Shanahan F, Duerr RH, Rotter JI, Yang H, Sutherland LR, McElree C, et al. Neutrophil autoantibodies in ulcerative colitis: familial aggregation and genetic heterogeneity. Gastroenterology 1992; 103: 456-61.
23. Seibold F, Slametschka D, Gregor M, Weber P. Neutrophil autoantibodies: a genetic marker in primary sclerosing cholangitis and ulcerative colitis. Gastroenterology 1994; 107: 532-6.
24. Targan SR, Landers CJ, MacDermott RP, Vidrich A. Gut mucosa is the site of antigenic B-cell priming and production of perinuclear antineutrophil cytoplasmic antibodies (p-ANCA) in patients with ulcerative colitis (UC). Gastroenterology 1995; 108: A926.