Lack of association between vitamin D receptor FokI polymorphism and alopecia areata

European Journal of Dermatology

Volumn 14, Issue 3, 2004, Pages 156-158

  Akar, Ahmet ^a   Orkunoglu, Funda Elif ^a   Ozata, Metin ^a   Sengul, Ali ^a   Gur, Ali Riza ^a  

^a GULHANE SCHOOL OF MEDICINE   (Turkey)

Author keywords

Alopecia areata; FokI restriction polymorphism; VDR; Vitamin D receptor gene

Indexed keywords

VITAMIN D RECEPTOR;

ADULT; ALLELE; ALOPECIA AREATA; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; CORRELATION COEFFICIENT; DISEASE ASSOCIATION; DNA FLANKING REGION; DNA POLYMORPHISM; FEMALE; GENOTYPE; HUMAN; MALE; POLYMERASE CHAIN REACTION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; STATISTICAL SIGNIFICANCE;

ADULT; ALOPECIA AREATA; CASE-CONTROL STUDIES; DEOXYRIBONUCLEASES, TYPE II SITE-SPECIFIC; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENOTYPE; HUMANS; MALE; POLYMORPHISM, GENETIC; RECEPTORS, CALCITRIOL; TURKEY;

EID: 2942567946     PISSN: 11671122     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. Stumpf WE, Koike N, Hayakawa N, Tokudo K, Nishimiyo K, Hirote J, Okozaki A, Kumaki K. Distribution of 1,25-dihydroxyvitamin D3[22-oxa] in vivo receptor binding in adult and developing skin. Arch Dermatol Res 1995; 287: 294-303.
2. Reichrath J, Collins ED, Epple S, Kerber A, Norman AW, Bahmer FA. Immunohistochemical detection of 1,25-dihydroxyvitamin D3 receptors (VDR) in human skin. A comparison of five antibodies. Pathol Res Pract 1996; 192: 281-9.
3. Reichrath J, Schilli M, Kerber A, Bahmer FA, Czarnetzki BM, Paus R. Hair follicle expression of 1,25-dihydroxyvitamin D3 receptors during the murine hair cycle. Br J Dermatol 1994; 131: 477-82.
4. Chen CH, Sakoi Y, Demay MB. Targeting expression of the humon vitamin D receptor to the kerotinocytes of vitamin D receptor null mice prevents alopecia. Endocrinology 2001; 142: 5386-9.
5. Xie Z, Komuves L, Yu QC, Elalieh H, Ng DC, Leory C, Chong S, Crumrine D, Yoshizawa T, Kato S, Bikle DD. Lack of the vitamin D receptor is associated with reduced epidermal differentiation and hair follicle growth. J Invest Dermatol 2002; 118: 11-6.
6. Reichrath J. Vitamin D and the Hair Follicle. In the Vitamin D in Dermatology. Edited by K Kragballe. Marcel Dekker, Inc, New York, 2000, pp. 111-21.
7. Li YC, Pirro AE, Amling M, Delling G, Baron R, Bronson R, Demay MB. Targeted ablation of the vitamin D receptor: an animal model of vitamin D-dependent rickets type II with alopecia. Proc Natl Acad Sci 1997; 94: 9831-5.
8. Sakai Y, Kishimoto J, Demay MB. Metabolic and cellular analysis of alopecia in vitamin D receptor knockout mice. J Clin Invest 2001; 107: 961-6.
9. Kalish RS, Gilhar A. The immunology of alopecia areata and potential application to novel therapies. Dermatol Ther 2001; 14: 322-8.
10. Ban Y, Taniyama M, Ban Y. Vitamin D receptor gene polymorphism is associated with Graves' disease in the Japanese population. J Clin Endocrinol Metab 2000; 85: 4639-43.
11. Saeki H, Asano N, Tsunemi Y, Takekoshi T, Kishimoto M, Mitsui H, Tada Y, Torii H, Komine M, Asahina A, Tamaki K. Polymorphisms of vitamin D receptor gene in Japanese patients with psoriasis vulgoris. J Dermatol Sci 2002; 30: 167-71.
12. Kaya TI, Erdol ME, Tursen U, Camdeviren H, Gunduz O, Soylemez F, Ikizoglu G. Association between vitamin D receptor gene polymorphism and psoriasis among the Turkish population. Arch Dermatol Res 2002; 294: 286-9.
13. Olsen E, Hordinsky M, McDonald-Hull S, Price V, Roberts J, Shapira J, Stenn K. Alopecia areata investigational assessment guidelines. J Am Acad Dermatol 1999; 40: 242-6.
14. Chiu KC, Chuang LM, Yoon C. The vitamin D receptor polymorphism in the translation initiation codon is a risk factor for insulin resistance in glucose tolerant Caucasians. BMC Med Genet 2001; 2: 2.
15. Kanan RM, Voranasi SS, Francis RM, Parker L, Datto HK. Vitamin D receptor gene start codon polymorphism (FokI) and bone mineral density in healthy male subjects. Clin Endocrinol 2000; 53: 93-8.
16. Park BS, Pork JS, Lee DY, Youn JI, Kim IG. Vitamin D receptor polymorphism is associated with psoriasis. J Invest Dermatol 1999; 112: 113-6.