Genotype and allele frequency of PAI-1 promoter polymorphism in healthy subjects from the west of Mexico. Association with biochemical and hematological parameters

Annales de Genetique

Volumn 47, Issue 2, 2004, Pages 155-162

  Ruiz Quezada, Sandra ^a   Vázquez Del Mercado, Mónica ^a   Parra Rojas, Isela ^b   Rangel Villalobos, Héctor ^a   Best Aguilera, Carlos ^c   Sánchez Orozco, Laura Verónica ^b   Muñoz Valle, José Francisco ^a  

^a UNIVERSITY OF GUADALAJARA   (Mexico)

^b HOSPITAL CIVIL DE GUADALAJARA FRAY ANTONIO ALCALDE   (Mexico)

^c HOSPITAL GENERAL DE OCCIDENTE   (Mexico)

Author keywords

Healthy subjects; Mexican population; PAI 1; Polymorphism; TG; VLDL

Indexed keywords

FIBRINOGEN; GENOMIC DNA; GLUCOSE; PLASMINOGEN ACTIVATOR INHIBITOR 1;

ADULT; AGED; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DEMOGRAPHY; DNA ISOLATION; DNA POLYMORPHISM; FEMALE; GENE DELETION; GENE FREQUENCY; GENE INSERTION; GENETIC SCREENING; GENOTYPE; HEMATOLOGICAL PARAMETERS; HUMAN; LEUKOCYTE; LIPID ANALYSIS; MALE; MEXICO; NORMAL HUMAN; PARAMETER; POLYMERASE CHAIN REACTION; POPULATION GENETICS; PROMOTER REGION; RESTRICTION MAPPING; STATISTICAL SIGNIFICANCE;

ADULT; FEMALE; GENE FREQUENCY; GENOTYPE; HEMATOLOGIC TESTS; HUMANS; LIPIDS; MALE; MEXICO; PLASMINOGEN ACTIVATOR INHIBITOR 1; POLYMORPHISM, GENETIC; PROMOTER REGIONS (GENETICS); REFERENCE VALUES;

INSERTION SEQUENCES;

EID: 2942566208     PISSN: 00033995     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.anngen.2003.12.001     Document Type: Article

References (25)

1. Henry M., Chomiki N., Scarabin P.Y., Alessi M.C., Peiretti F., Arveiler D., Ferrieres J., Evans A., Amouyel P., Poirier O., Cambien F., Juhan-Vague I. Five frequent polymorphism of the PAI-1 gene: lack of association between genotypes, PAI activity, and triglycerides levels in a healthy population. Arterioscler. Thromb. Biol. 17:1997;851-858
2. Kohler H.P., Grant P.J. Mechanisms of disease: plasminogen-activator inhibitor type 1 and coronary artery disease. N. Engl. J. Med. 342:2000;1801-1972
3. Loskutoff D.J., Samad F. The adipocyte and hemostatic balance in obesity: studies of PAI-1. Arterioscler. Thromb. Vasc. Biol. 18:1998;1-6
4. Hoylaerts M., Rijken D.C., Lijnen H.R., Collen D. Kinetics of the activation of plasminogen by human tissue plasminogen activator: role of fibrin. J. Biol. Chem. 257:1982;2912-2919
5. Higgins D.L., Vehar G.A. Interaction of one-chain and two-chain tissue plasminogen activator with intact and plasmin-degraded fibrin. Biochemistry. 26:1987;7786-7791
6. Eriksson P., Kallin B., van't Hooft F.M., Bavenholm P., Hamsten A. Allele-specific increase in basal transcription of the plasminogen-activator inhibitor 1 gene is associated with myocardial infarction. Proc. Natl. Acad. Sci. USA. 92:1995;1851-1855
7. Dawson S.J., Wiman B., Hamsten A., Green F., Humphries S., Henney A.M. The two allele sequences of a common polymorphism in the promoter of the plasminogen activator-1 (PAI-1) gene respond differently to interleukin-1 in HepG2 cells. J. Biol. Chem. 268:1993;10739-10745
8. Wong T.Y., Poon P., Szeto C.C., Chan J.C., Li P.K. Association of plasminogen activator inhibitor-1 4G/4G genotype and type 2 diabetic nephropathy in Chinese patients. Kidney Int. 57:2000;632-638
9. Margaglione M., Cappucci G., Colaizzo D., Giuliani N., Vecchione G., Grandone E., Pennelli O., Di Minno G. The PAI-1 Gene Locus 4G/5G polymorphism is associated with a family History of coronary artery disease. Arterioscler. Thromb. Vasc. Biol. 18:1998;152-156
10. Margaglione M., Cappucci G., d'Addedda M., Colaizzo D., Giuliani N., Vecchione G., Mascolo G., Grandone E., Di Minno G. PAI-1 plasma levels in a general population without clinical evidence of atherosclerosis: relation to environmental and genetic determinants. Arterioscler. Thromb. Biol. 18:1998;562-567
11. Morange P.E., Henry M., Tregouët D., Granel B., Aillaud M.F., Alessi M.C., Juhan-Vague I. The A -844 G polymorphism in the PAI-1 gene is associated with a higher risk of venous thrombosis in factor V Leiden Carriers. Arterioscler. Thromb. Vasc. Biol. 20:2000;1387-1391
12. van der Laan W.H., Slagboom P.E., MeulenbeltI I., Verheijen J.H., Breedveld F.C., Huizinga T.W.J. A functional polymorphism in the promotor of plasminogen activator inhibitor-1 is associated with join destruction in RA. Arthritis Rheum. 41:1998;S60
13. Tàssies D., Espinosa G., Muñoz-Rodríguez F.J., Freire C., Cervera R., Monteagudo J., Maragall S., Escolar G., Ingelmo M., Ordinas A., Font J., Reverter J.C. The 4G/5G polymorphism of the type 1 plasminogen activators inhibitor gene and thrombosis in patients with antiphospholipid syndrome. Arthritis Rheum. 43:2000;2349-2358
14. McCormack L.J., Nagi D.K., Stickland M.H., Mansfield M.W., Mohamed-Ali V., Yudkin J.S., Knowler W.C., Grant P.J. Promoter (4G/5G) plasminogen activator inhibitor-1 genotype in Pima Indians: relationship to plasminogen activator inhibitor-1 levels and features of the insulin resistance syndrome. Diabetologia. 39:1996;1512-1518
15. Nilsson L., Banfi C., Diczfalusy U., Tremoli E., Hamsten A., Eriksson P. Unsaturated fatty acids increase plasminogen activator inhibitor-1 expression in endothelial cells. Arterioscler. Thromb. Vasc. Biol. 18:1998;1679-1685
16. Lisker R. Estructura genética de la población mexicana. 1981;Salvat, México
17. Miller S.A., Dykes D.D., Polesky H.F. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res. 16:1988;1215
18. Margalione M., Grandone E., Cappucci G., Colaizzo D., Giuliani N., Vecchione G., dÁddedda M., Di Minno G. An alternative method for PAI-1 promoter polymorphism (4G/5G) typing. Tromb. Haemost. 77:1997;605-606
19. Ridker P.M., Hennekens C.H., Lindpaintner K., Stampfer M.J., Miletich J.P. Arterial and venous thrombosis is not associated with the 4G/5G polymorphism in the promoter of the plasminogen activator inhibitor gene in a large cohort of US men. Circulation. 95:1997;59-62
20. Wang A.Y., Poon P., Lai F.M., Yu L., Choi P.C., Lui S.F., Li P.K. Plasminogen activator inhibitor-1 gene polymorphism 4G/4G genotype and lupus nephritis in Chinese patients. Kidney Int. 59:2001;1520-1528
21. Nowak-Gottl U., Strater R., Kosch A., von Echkardstein A., Schobess R., Luigs P., Nabel P., Vielhaber H., Kurnik K., Junker R. The plasminogen activator inhibitor (PAI)-1 promoter 4G/4G genotype is not associated with ischemic stroke in a population of German children. Eur. J. Haematol. 66:2001;57-62
22. Hermans P.W.M., Hibberd M.L., Booy R., Daramola O., Hazelzet J.A., de Groot R., Levin M. 4G/5G promoter polymorphism in the plasminogen-activator- inhibitor-1 gene and outcome of meningococcal disease. Lancet. 354:1999;556-560
23. Westendorp R.G.J., Hottenga J.J., Slagboom P.E. Variation in plasminogen-activator-inhibitor-1 gene and risk of meningococcal septic shock. Lancet. 354:1999;561-563
24. Gorodezky C., Alaez C., Vázquez-García M.N., De la Rosa G., Infante E., Balladares S., Toribio R., Pérez-Luque E., Muñoz L. The genetic structure of Mexican Mestizos of different locations: tracking back their origins through MHC genes, blood group systems, and microsatellites. Human Immunol. 62:2001;979-991
25. INEGI, Instituto Nacional de Estadística Geografía e Informática. Tabulados Básico de los Estados Unidos Mexicanos. XII Censo general de población y vivienda:2000