No association between two MLH3 variants (S845G and P844L)and colorectal cancer risk

Cancer Genetics and Cytogenetics

Volumn 152, Issue 1, 2004, Pages 70-71

  De Jong, Mirjam M ^a   Hofstra, Robert M W ^a   Kooi, Krista A ^a   Westra, Jantine L ^a   Berends, Maran J W ^a   Wu, Ying ^a   Hollema, Harry ^a   Van Der Sluis, Tineke ^a   Van Der Graaf, Winette T A ^a   De Vries, Elisabeth G E ^a   Schaapveld, Michael ^b   Sijmons, Rolf H ^a   Te Meerman, Gerard J ^a   Kleibeuker, Jan H ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^b Integraal Kankercentrum Noord Nederland   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CANCER CLASSIFICATION; CANCER RISK; COLORECTAL CANCER; CONTROLLED STUDY; DISEASE ASSOCIATION; EXON; GENE; GENE MUTATION; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GERM LINE; HUMAN; MAJOR CLINICAL STUDY; MISSENSE MUTATION; MLH3 GENE; PRIORITY JOURNAL;

CARRIER PROTEINS; CASE-CONTROL STUDIES; COLORECTAL NEOPLASMS, HEREDITARY NONPOLYPOSIS; GENETIC PREDISPOSITION TO DISEASE; GENETIC SCREENING; HUMANS; MUTATION; RISK FACTORS; VARIATION (GENETICS);

EID: 2942556714     PISSN: 01654608     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cancergencyto.2003.10.008     Document Type: Article

References (4)

1. Wu Y., Berends M.J., Sijmons R.H., Mensink R.G., Verlind E., Kooi K.A., van der Sluis T., Kempinga C., van der Zee A.G., Hollema H., Buys C.H., Kleibeuker J.H., Hofstra R.M. A role for MLH3 in hereditary nonpolyposis colorectal cancer. Nat Genet. 29:2001;137-138
2. Vasen H.F., Watson P., Mecklin J.P., Lynch H.T. New clinical criteria for hereditary nonpolyposis colorectal cancer (HNPCC, Lynch syndrome) proposed by the International Collaborative Group on HNPCC. Gastroenterology. 116:1999;1453-1456
3. Berends M.J., Wu Y., Sijmons R.H., Mensink R.G., van der Sluis T., Hordijk-Hos J.M., de Vries E.G., Hollema H., Karrenbeld A., Buys C.H., van der Zee A.G., Hofstra R.M., Kleibeuker J.H. Molecular and clinical characteristics of MSH6 variants: an analysis of 25 index carriers of a germline variant. Am J Hum Genet. 70:2002;26-37
4. de Jong M.M., Nolte I.M., te Meerman G.J., van der Graaf W.T., de Vries E.G., Sijmons R.H., Hofstra R.M., Kleibeuker J.H. Low-penetrance genes and their involvement in colorectal cancer susceptibility. Cancer Epidemiol Biomarkers Prev. 11:2002;1332-1352