Unreported deviations of genotype distributions from Hardy-Weinberg equilibrium in articles published in Critical Care Medicine between 1999 and 2003 [2]

Critical Care Medicine

Volumn 32, Issue 6, 2004, Pages 1431-1433

  Németh, Éva ^a   Vásárhelyi, Barna ^a   Györffy, Balázs ^a   Kocsis, István ^a  

^a SEMMELWEIS UNIVERSITY   (Hungary)

Author keywords

[No Author keywords available]

Indexed keywords

ALLELE; BLOOD DONOR; CALCULATION; COMPUTER PROGRAM; CYTOKINE RESPONSIVE ELEMENT; EQUILIBRIUM CONSTANT; GENE MUTATION; GENETIC POLYMORPHISM; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOTYPE; HETEROZYGOSITY; HUMAN; INTENSIVE CARE; INTENSIVE CARE UNIT; LETTER; MEDICAL EXAMINATION; MEDICAL INFORMATION; PRIORITY JOURNAL; PUBLISHING;

EID: 2942554993     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.CCM.0000129023.46634.F8     Document Type: Letter

References (18)

1. Hardy GH: Mendelian proportions in a mixed population. Science 1908; 28:49-50
2. Weinberg W: Über den Nachweis der Vererbung beim Menchen. Jahresh Verein f Vaterl Naturk in Wüttemberg 1908; 64:368-382
3. Schroeder S, Reck M, Hoeft A, et al: Analysis of two human leukocyte antigen-linked polymorphic heat shock protein 70 genes in patients with severe sepsis. Crit Care Med 1999; 27:1265-1270
4. Fang XM, Schroder S, Hoeft A, et al: Comparison of two polymorphisms of the interleukin-1 gene family: Interleukin-1 receptor antagonist polymorphism contributes to susceptibility to severe sepsis. Crit Care Med 1999; 27:1330-1334
5. Schindler K, Zauner C, Buchmayer H et al: High prevalence of hyperhomocysteinemia in critically ill patients. Crit Care Med 2000; 28:991-995
6. Buchmayer H, Sunder-Plassmann G, Hirschl MM, et al: G-protein beta3 subunit gene (GNB3) polymorphism 825C->T in patients with hypertensive crisis. Crit Care Med 2000; 28:3203-3206
7. Hubacek JA, Stuber F, Frohlich D, et al: Gene variants of the bactericidal/permeability increasing protein and lipopolysaccharide binding protein in sepsis patients: Gender-specific genetic predisposition to sepsis. Crit Care Med 2001; 29:557-561
8. Schluter B, Raufhake C, Erren M, et al: Effect of the interleukin-6 promoter polymorphism (-174 G/C) on the incidence and outcome of sepsis. Crit Care Med 2002; 30:32-37
9. Heesen M, Bloemeke B, Heussen N, et al: Can the interleukin-6 response to endotoxin be predicted? Studies of the influence of a promoter polymorphism of the interleukin-6 gene, gender, the density of the endotoxin receptor CD14, and inflammatory cytokines. Crit Care Med 2002; 30:664-669
10. Gibot S, Cariou A, Drouet L, et al: Association between a genomic polymorphism within the CD14 locus and septic shock susceptibility and mortality rate. Crit Care Med 2002; 30:969-973
11. Reid CL, Perrey C, Pravica V, et al: Genetic variation in proinflammatory and anti-inflammatory cytokine production in multiple organ dysfunction syndrome. Crit Care Med 2002; 30:2216-2221
12. Sunder-Plassmann G, Kittler H, Eberle C, et al: Angiotensin converting enzyme DD genotype is associated with hypertensive crisis. Crit Care Med 2002; 30:2236-2241
13. Lowe PR, Galley HF, Abdel-Fattah A, et al: Influence of interleukin-10 polymorphisms on interleukin-10 expression and survival in critically ill patients. Crit Care Med 2003; 31:34-38
14. Heesen M, Kunz D, Bachmann-Mennenga B, et al: Linkage disequilibrium between tumor necrosis factor (TNF)-alpha-308 G/A promoter and TNF-beta NcoI polymorphisms: Association with TNF-alpha response of granulocytes to endotoxin stimulation. Crit Care Med 2003; 31:211-214
15. Schneider S, Roessli D, Excoffier L: Arlequin ver. 2.000: A Software for Population Genetics Data Analysis. Genetics and Biometry Laboratory, University of Geneva, Switzerland. 2000. Available online at: http://lgb.unige.ch/arlequin/
16. Guo SW, Thompson EA: Performing the exact test of Hardy-Weinberg proportion for multiple alleles. Biometrics 1992; 48:361-372
17. Kramer J, Fülöp T, Rajczy K, et al: A marked drop in the incidence of the null allele of the B gene of the fourth component of complement (C4B*Q0) in elderly subjects: C4B*Q0 as a probable negative selection factor for survival. Hum Genet 1991; 86:595-598
18. Randolph AG: Mining for the genetic determinants of septic shock: When is it really gold? Crit Care Med 2002; 30:1161-1163