Sedation in children undergoing CT scan or MRI: Effect of time-course and tolerance of rectal chloral hydrate

Fundamental and Clinical Pharmacology

Volumn 18, Issue 3, 2004, Pages 347-350

  Treluyer, Jean Marc ^a   Andre, Christine ^b   Carp, Pierre François Ceccaldi ^a   Chalumeau, Martin ^a   Tonnelier, Sylvie ^a   Cuq, Cédric ^a   Kalifa, Gabriel ^b   Pons, Gérard ^a   Adamsbaum, Catherine ^b  

^a UNIVERSITÉ PARIS DESCARTES   (France)

^b Service de Radiologie   (France)

Author keywords

Children; Chloral hydrate; Computerized tomography scan; Magnetic resonance imaging; Rectal route; Sedation

Indexed keywords

CHLORAL HYDRATE; OXYGEN;

APNEA; ARTICLE; BREATHING RATE; CLINICAL ARTICLE; CLINICAL TRIAL; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIARRHEA; DIASTOLIC BLOOD PRESSURE; DRUG EFFECT; DRUG FORMULATION; DRUG SAFETY; DRUG TOLERANCE; FEMALE; HEART RATE; HUMAN; HYPERSALIVATION; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; OXYGEN SATURATION; PRESCHOOL CHILD; PRIORITY JOURNAL; RADIOLOGIST; SCORING SYSTEM; SEDATION; SIDE EFFECT; SYSTOLIC BLOOD PRESSURE; X RAY;

ADMINISTRATION, RECTAL; CHILD, PRESCHOOL; CHLORAL HYDRATE; FEMALE; HUMANS; HYPNOTICS AND SEDATIVES; INFANT; MAGNETIC RESONANCE IMAGING; MALE; TOMOGRAPHY, X-RAY COMPUTED;

EID: 2942552231     PISSN: 07673981     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1472-8206.2004.00232.x     Document Type: Article

References (16)

1. Frush D.P., Bisset G.S. III, Hall S.C. Pediatric sedation in radiology: the practice of safe sleep. Am. J. Roentgenol. (1996) 167 1381-1387.
2. Ronchera-Oms C.L., Casillas C., Marti-Bonmati L. et al. Oral chloral hydrate provides effective and safe sedation in paediatric magnetic resonance imaging. J. Clin. Pharm. Ther. (1994) 19 239-243.
3. Napoli K.L., Ingall G.C., Martin G.R. Safety and efficacy of chloral hydrate sedation in children undergoing echocardiography. J. Pediatr. (1996) 129 287-291.
4. Hubbard A.M., Markowitz R.I., Kimmel B., Kroger M., Bartko M.B. Sedation for pediatric patients undergoing CT and MRI. J. Comput. Assist. Tomogr. (1992) 16 3-6.
5. Pereira J.K., Burrows P.E., Richards H.M., Chuang S.H., Babyn P.S. Comparison of sedation regimens for pediatric outpatient CT. Pediatr. Radiol. (1993) 23 341-344.
6. Beebe D.S., Tran P., Bragg M., Stillman A., Truwitt C., Belani K.G. Trained nurses can provide safe and effective sedation for MRI in pediatric patients. Can. J. Anaesth. (2000) 47 205-210.
7. Chung T., Hoffer F.A., Connor L., Zurakowski D., Burrows P.E. The use of oral pentobarbital sodium (Nembutal) versus oral chloral hydrate in infants undergoing CT and MR imaging - a pilot study. Pediatr. Radiol. (2000) 30 332-335.
8. Dacher J.N., Neuenschwander S., Monroc M., Vanier A., Eurin D., Le Dosseur P. Sedation with oral hydroxyzine and rectal chloral hydrate in pediatric MRI and CT. J. Radiol. (1996) 77 1189-1192.
9. Saint-Maurice C., Meistelman C., Rey E., Esteve C., de Lauture D., Olive G. The pharmacokinetics of rectal midazolam for premedication in children. Anesthesiology (1986) 65 536-538.
10. Huault G., Labrune B. Pédatrie d'Urgences, Médecine- Sciences Flammarion, 1993.
11. Kao S.C., Adamson S.D., Tatman L.H., Berbaum K.S. A survey of post-discharge side effects of conscious sedation using chloral hydrate in pediatric CT and MR imaging. Pediatr. Radiol. (1999) 29 287-290.
12. Marti-Bonmati L., Ronchera-Oms C.L., Casillas C., Poyatos C., Torrijo C., Jimenez N.V. Randomised double blind clinical trial of intermediate versus high dose chloral hydrate for neuroimaging of children. Neuroradiology (1995) 37 687-691.
13. Malviya S., Voepel-Lewis T., Prochaska G., Tait A.R. Prolonged recovery and delayed side effects of sedation for diagnostic imaging studies in children. Pediatrics (2000) 105 E42.
14. Daniel F.B., DeAngelo A.B., Stober J.A., Olson G.R., Page N.P. Hepatocarcinogenicity of chloral hydrate, 2-chloroacetaldehyde, and dichloroacetic acid in the male B6C3F1 mouse. Fundam. Appl. Toxicol. (1992) 19 159-168.
15. Rijhsinghani K.S., Abrahams C., Swerdlow M.A., Rao K.V., Ghose T. Induction of neoplastic lesions in the livers of C57BL x C3HF1 mice by chloral hydrate. Cancer Detect. Prev. (1986) 9 279-288.
16. Mueller L., Kasper P., Kersten B., Kaufman G. Induction of micronuclei by chloral hydrate (CH) in CYP2E1 competent cells and in rat hepatocytes. Environ. Mol. Mutagen. (1999) 35 46.