Synthesis of glycosyl-isoindigo derivatives

Tetrahedron Letters

Volumn 45, Issue 25, 2004, Pages 4827-4830

  Sassatelli, Mathieu ^a   Saab, Elias ^a   Anizon, Fabrice ^a   Prudhomme, Michelle ^a   Moreau, Pascale ^a  

^a UNIVERSITÉ CLERMONT AUVERGNE   (France)

Author keywords

Indigo ds; Isoindigos; Kinases inhibitors

Indexed keywords

1 (BETA DEXTRO GLUCOPYRANOSYL)ISOINDIGO; INDOLE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; DRUG STRUCTURE; DRUG SYNTHESIS;

EID: 2942541689     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2004.04.167     Document Type: Article

References (15)

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10. 4, and concentrated under vacuum to give a residue, which was purified by flash chromatography (eluent cyclohexane/EtOAc 80:20). Compound 16 was obtained as red crystals (mp = 205°C) with 40% yield
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12. 4, and concentrated under vacuum to give a residue, which was purified by chromatography (eluent EtOAc/MeOH from 95:5 to 85:15). The glycosyl isoindigo 19 was obtained as a red solid (mp > 300°C) in 60% yield
13. ′a), 167.0, 168.7 (C=O)
14. quat. arom.), 166.6, 168.7 (C=O)
15. quat. arom.), 167.1, 168.7 (C=O)