Macrolide resistance phenotypes of commensal viridans group streptococci and Gemella spp. and PCR detection of resistance genes

International Journal of Antimicrobial Agents

Volumn 23, Issue 6, 2004, Pages 582-589

  Zolezzi, P Cerdá ^a   Calvo, M C Rubio ^a   Millan L ^a   Goni P ^a   Canales, M ^a   Capilla, S ^a   Duran E ^a   Gomez Lus R ^a  

^a HOSPITAL CLÍNICO UNIVERSITARIO LOZANO BLESA   (Spain)

Author keywords

Antibiotic susceptibilities; Gemella spp.; Macrolides; Resistance genes; Viridans group streptococci

Indexed keywords

AZITHROMYCIN; CHLORAMPHENICOL; CLINDAMYCIN; DALFOPRISTIN PLUS QUINUPRISTIN; ERYTHROMYCIN; GENTAMICIN; KANAMYCIN; LINEZOLID; MACROLIDE; MINOCYCLINE; MIOKAMYCIN; SPECTINOMYCIN; STREPTOMYCIN; TELITHROMYCIN; TETRACYCLINE;

ALPHA HEMOLYTIC STREPTOCOCCUS; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL STRAIN; BACTERIUM ISOLATE; CONTROLLED STUDY; GEMELLA; GENE IDENTIFICATION; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PHENOTYPE; PREVALENCE; PRIORITY JOURNAL;

ACETAMIDES; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; DRUG RESISTANCE; ERYTHROMYCIN; GENES, BACTERIAL; HUMANS; KETOLIDES; MACROLIDES; MEMBRANE PROTEINS; METHYLTRANSFERASES; MICROBIAL SENSITIVITY TESTS; OXAZOLIDINONES; STAPHYLOCOCCACEAE; STREPTOGRAMIN B; TETRACYCLINE RESISTANCE; VIRGINIAMYCIN; VIRIDANS STREPTOCOCCI;

EID: 2942541558     PISSN: 09248579     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijantimicag.2003.10.014     Document Type: Article

References (50)

1. Kennedy H.F., Gemmell C.G., Bagg J., Gibson B.E.S., Michie J.R. Antimicrobial susceptibility of blood cultures isolates of viridans group streptococci: relationship to a change in empirical antibiotic therapy in febrile neutropenia. J. Antimicrob. Chemother. 47:2001;693-696
2. Douglas C.W.I., Heath J., Hampton K., Preston F.E. Identity of viridans streptococci isolated from cases of infective endocarditis. J. Med. Microbiol. 39:1993;179-182
3. Fresard A., Michel V.P., Rueda X., Aubert G., Dorche G., Lucht F. Gemella haemolysans endocarditis. Clin. Infect. Dis. 16:1993;586-587
4. Omran Y., Wood C.A. Endovascular infection and septic arthritis caused by Gemella morbillorum. Diagn. Microbiol. Infect. Dis. 16:1993;131-134
5. La Scola B., Didier R. Molecular identification of Gemella species from three patients with endocarditis. J. Clin. Microbiol. 36:1998;866-871
6. Alcaide F., Catarrala J., Linares J., Gudiol F., Martin R. In vitro activities of eight macrolide antibiotics and RP-59500 (quinupristin/ dalfopristin) against viridans group streptococci isolated from blood of neutropenic cancer patients. Antimicrob. Agents. Chemother. 40:1996;2117-2120
7. Akiyama K., Taniyasu N., Hirota J., Iba Y., Maisawa K. Recurrent aortic valve endocarditis caused by Gemella morbillorum. Report of a case and review of the literature. Jpn. Circ. J. 65:2001;997-1000
8. Goldstein F.W., Acar J.F. the Alexander Project Collaborative Group Antimicrobial resistance among lower respiratory tract isolates of Streptococcus pneumoniae: results of a 1992-93 western Europe and USA collaborative surveillance study. The Alexander Project Collaborative Group. J. Antimicrob. Chemother. 38:1996;71-84
9. Ono T., Shiota S., Hirota K., Nemoto K., Tsuchiya T., Miyake Y. Susceptibilities of oral and nasal isolates of Streptococcus mitis and Streptococcus oralis to macrolides and PCR detection of resistance genes. Antimicrob. Agents Chemother. 44:2000;1078-1080
10. Leclerq R., Courvalin P. Bacterial resistance to macrolides, lincosamide and streptogramin antibiotics by target modification. Antimicrob. Agents Chemother. 35:1991;1267-1272
11. Leclercq R. Mechanisms of resistance to macrolides and lincosamides: nature of the resistance elements and their clinical implications. Clin. Infect. Dis. 34:2002;482-492
12. Clancy J., Petitpas J., Did-Hajj F., et al. Molecular cloning and functional analysis of a novel macrolide-resistance determinant, mefA, from Streptococcus pyogenes. Mol. Microbiol. 22:1996;867-879
13. Tait-Kamradt A., Clancy J., Cronan M., et al. mefE is necessary for the erythromycin-resistance M phenotype in Streptococcus pneumoniae. Antimicrob. Agents Chemother. 41:1997;2251-2255
14. Sutcliffe J., Tait-Kamradt A., Wondrack L. Streptococcus pneumoniae and Streptococcus pyogenes resistant to macrolides but sensitive to clindamycin: a common resistance pattern mediated by an efflux system. Antimicrob. Agents Chemother. 40:1996;1817-1824
15. Del Grosso M., Iannelli F., Messina C., et al. Macrolide efflux genes mef(A) and mef(E) are carried by different genetic elements in Streptococcus pneumoniae. J. Clin. Microbiol. 40:2002;774-778
16. Doern G.V., Ferraro M.J., Brueggemann A.B., Ruolff K.L. Emergence of high rates of antimicrobial resistance among viridans group streptococci in US. Antimicrob. Agents Chemother. 40:1996;891-894
17. Teng L.J., Hsueh P.R., Chen Y.C., Ho S.W., Luh K.T. Antimicrobial susceptibility of viridans group streptococci in Taiwan with an emphasis on the high rates of resistance to penicillin and macrolides in Streptococcus oralis. J. Antimicrob. Chemother. 41:1998;621-627
18. Ioannidou S., Tassios P.T., Kotsovili-Tseleni A., Foustoukou M., Legakis N.J., Vatopoulus A. Antibiotic resistance rates and macrolide resistance phenotypes of viridans group streptococci from the oropharynx of healthy Greek children. Int. J. Antimicrob. Agents. 17:2001;195-201
19. Aracil B., Miñambres M., Oteo J., Torres C., Gómez- Garcés J.L., Alós J.I. High prevalence of erythromycin-resistant and clindamycin-susceptible (M phenotype) viridans group streptococci from pharyngeal samples: a reservoir of mef genes in commensal bacteria. J. Antimicrob. Chemother. 48:2001;592-594
20. pc194 and the integrase gene of Tn1545 in clinical Streptococcus pneumoniae harbouring erm(B) and mef(A) genes in Spain. J. Antimicrob. Chemother. 47:2001;863-866
21. Facklam R. What happened to the streptococci: overview of taxonomic and nomenclature changes. Clin. Microbiol. Rev. 15:2002;613-630
22. Seppälä H., Nissinen A., Yu Q., Huovinen P. Three different phenotypes of erithromycin-resistant Streptococcus pyogenes in Finland. J. Antimicrob. Chemother. 32:1993;885-891
23. Malke H. Zonal-pattern resistance to lincomycin in Streptococcus pyogenes: genetic and physical studies. In: Schlessinger D, editor. Microbiology. Washington, DC: American Society for Microbiology; 1982. p. 142-5.
24. National Committee for Clinical Laboratory Standards. Performance standards for antimicrobial disk susceptibility test. 6th ed. Approved standard M2-A6. Wayne, PA: National Committee for Clinical Laboratory Standards; 1997.
25. National Committee for Clinical Laboratory Standards. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically. 5th ed. Approved standard M7-A5. Wayne, PA: National Committee for Clinical Laboratory Standards; 2000.
26. National Committee for Clinical Laboratory Standards. Performance standards for susceptibility testing (1982): tenth informational supplement M100-S10 (M7). Wayne, PA: National Committee for Clinical Laboratory Standards; 2000.
27. Comité de l'Antibiogramme de la Societé Française de Microbiologie. Communiqué 1999. París: Societé Francaise de Microbiologie; 1999.
28. Ausubel FM, Brent R, Kingstron E, Moore DD, Seidman JG, Smith JA. In: Struhl K, editor. Currents protocols in molecular biology. New York: John Wiley & Sons Inc.; 1987.
29. Sutcliffe J., Grebe T., Tait-Kamradt A., Wondrack L. Detection of erythromycin-resistant determinants by PCR. Antimicrob. Agents Chemother. 40:1996;2562-2566
30. Seppälä H., Skurnik M., Soini H., Roberts M.C., Huovinen P. A novel erythromycin resistance methylase gene (ermTR) in Streptococcus pyogenes. Antimicrob. Agents Chemother. 42:1998;257-262
31. De Azavedo J.C.S., Trpeski L., Pong-Porter S., Matsumura S. The Canadian Bacterial Surveillance Network, Low D.E. In vitro activities of fluoroquinolones against antibiotic-resistant blood culture isolates of viridans group streptococci from across Canada. Antimicrob. Agents. Chemother. 43:1999;2299-2301
32. Rodriguez-Avial I., Rodriguez-Avial C., Culebras E., Benítez A., Picazo J.J. Distribution of mef(A) and erm(B) genes in macrolide-resistant blood isolates of viridans group streptococci. J. Antimicrob. Chemother. 47:2001;727-728
33. Rodriguez-Avial C., García M.M., Rodriguez-Avial I., Picazo J.J. Fenotipos de resistencia a macrólidos, lincosamidas y estreptograminas en Streptococcus del grupo viridans aislados de hemocultivos. Rev. Esp. Quimioter. 12:1999;346-351
34. Arpin C., Canron M.H., Maugein J., Quentin C. Incidence of mefA and mefE genes in viridans group streptococci. Antimicrob. Agents Chemother. 43:1999;2335-2336
35. Gordon K.A., Beach M.L., Biedenbach D.J., Jones R.N., Rhomberg P.R., Mutnick A.H. Antimicrobial susceptibility patterns of β-hemolytic and viridans group streptococci: report from the SENTRY Antimicrobial Surveillance Program (1997-2000). Diagn. Microbiol. Infect. Dis. 43:2002;157-162
36. Poutanen SM, De Azavedo J, Willey B, Low DE, MacDonald KS. Molecular characterization of multidrug resistance in Streptococcus mitis. Antimicrob Agents Chemother; 1999. p. 1505-7.
37. Jacobs J.A., van Barr G.J., London N.H.H.J., et al. Prevalence of macrolide resistance genes in clinical isolates of the Streptococcus anginosus ('S. milleri') group. Antimicrob. Agents Chemother. 45:2001;2375-2377
38. Luna V.A., Coates P., Eady E.A., Cove J.H., Nguyen T.T., Roberts M.C. A variety of Gram-positive bacteria carry mobile mef genes. J. Antimicrob. Chemother. 44:1999;19-25
39. Johnston N.J., De Azavedo C., Kellner J.D., Low D.E. Prevalence and characterization of the mechanisms of macrolide, lincosamide, and streptogramin in resistance isolates of Streptococcus pneumoniae. Antimicrob. Agents Chemother. 42:1998;2425-2426
40. Betriu C., Redondo M., Palau M.L., et al. Comparative in vitro activities of linezolid, quinupristin-dalfopristin, moxifloxacin, and trovafloxacin against erythromycin-susceptible and -resistant streptococci. Antimicrob. Agents Chemother. 44:2000;1838-1841
41. Alcaide F., Benítez M.A., Catarrala J., Gudiol F., Liñares J., Martín R. In vitro activities of the new ketolide HMR 3647 (telithromycin) in comparison with those of eight other antibiotics against viridans group streptococci isolated from blood of neutropenic patients with cancer. Antimicrob. Agents Chemother. 45:2001;624-626
42. Casellas J.M., Visser M., Mac Dougall N. Estudio multicéntrico en el cono sur americano de la actividad comparativa in vitro de telitromicina en cepas con fenotipos definidos de resistencia asociadas a infecciones respiratorias adquiridas en la comunidad. Rev. Esp. Quimioter. 14:2001;269-274
43. Rice L. Tn916 family conjugative transposons and dissemination of antimicrobial resistance determinants. Antimicrob. Agents Chemother. 42:1998;1871-1877
44. Clermont D., Horaud T. Identification of chromosomal antibiotic resistance genes in Streptococcus anginosus ('S. milleri'). Antimicrob. Agents Chemother. 34:1990;1685-1690
45. Ounissi H., Derlot E., Carlier C., Courvalin P. Gene homogeneity for aminoglycoside-modifying enzymes in Gram-positive cocci. Antimicrob. Agents Chemother. 34:1990;2164-2168
46. Horodniceanu T., Buu-Hoï A., Delbos F., Bieth G. High-level aminoglycoside resistance in group A, B, G, D (Streptococcus bovis), and viridans group streptococci. Antimicrob. Agents Chemother. 21:1982;176-179
47. Farber B.F., Yee Y. High-level aminoglycoside resistance mediated by aminoglycoside-modifying enzymes among viridans streptococci. J. Infect. Dis. 155:1987;948-953
48. Kaufhold A., Potgieter E. Chromosomally mediated high-level gentamicin resistance in Streptococcus mitis. Antimicrob. Agents Chemother. 37:1993;2740-2742
49. Mutnick A.H., Biedenbach D.J., Turnidge J.D., Jones R.N. Spectrum and potency evaluation of a new oxazolidinone, linezolid: report from the SENTRY Antimicrobial Surveillance Program, 1998-2000. Diagn. Microbiol. Infect. Dis. 43:2002;65-73
50. Buu-Hoï A., Sapoetra A., Branger C., Acar J.F. Antimicrobial susceptibility of Gemella haemolysans isolated from patients with subacute endocarditis. Eur. J. Clin. Microbiol. 1:1982;102-106