Recombinant fibronectin polypeptide antagonizes hepatic failure induced by endotoxin in mice

Acta Pharmacologica Sinica

Volumn 25, Issue 6, 2004, Pages 783-788

  Wu, Yong ^a   Chen, Yuan Zhong ^a   Huang, Hui Fang ^a   Chen, Ping ^a  

^a FUJIAN MEDICAL UNIVERSITY   (China)

Author keywords

Acetylgalactosamine; Fibronectins; Lipopolysaccharides; Recombinant fusion proteins

Indexed keywords

BACTERIUM LYSATE; BIOTIN; COMPLEMENTARY DNA; DNA FRAGMENT; FIBRONECTIN; GALACTOSAMINE; ISOLEUCINE; PLASMID VECTOR; POLYPEPTIDE; RECOMBINANT HUMAN FIBRONECTIN; RECOMBINANT PROTEIN; TYROSINE; UNCLASSIFIED DRUG;

AFFINITY CHROMATOGRAPHY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ADHESION; CELL STRAIN BHK; CELL ULTRASTRUCTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISEASE MODEL; DRUG EFFECT; DRUG EFFICACY; HISTOLOGY; HISTOPATHOLOGY; LIVER CELL; LIVER FAILURE; LIVER INJURY; MALE; MOUSE; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PREVENTION; PROTEIN EXPRESSION; SUPERNATANT; SURVIVAL RATE;

ANIMALS; APOPTOSIS; CELL ADHESION; CELLS, CULTURED; CRICETINAE; ENDOTOXEMIA; FIBRONECTINS; GALACTOSAMINE; HUMANS; KIDNEY; LIPOPOLYSACCHARIDES; LIVER; LIVER FAILURE; MALE; MICE; MICE, INBRED BALB C; PEPTIDE FRAGMENTS; RECOMBINANT PROTEINS;

EID: 2942539579     PISSN: 16714083     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. Giancotti FG, Ruoslahti E. Integrin signaling. Science 1999; 285: 1028-32.
2. Yamada KM. Fibronectin peptides in cell migration and wound repair. J Clin Invest 2000; 105: 1507-9.
3. Potts JR, Campbell ID. Struture and function of fibronectin modules. Matrix Biol 1996; 15: 313-20.
4. Xia P, Culp LA. Adhesion activity in fibronectin's alternatively spliced domain EDa (EIIIA): complementarity to plasma fibronectin functions. Exp Cell Res 1995; 217: 517-27.
5. Aota S, Nomizu M, Yamada KM. The short amino acid sequence Pro-His-Ser-Arg-Asn in human fibronectin enhances cell-adhesive function. J Biol Chem 1994; 269: 24756-61.
6. Mas A, Rodes J. Fulminant hepatic failure. Lancet 1997; 349: 1081-5.
7. Wu Y, Chen YZ, Lu LH. Fibronectin supports endotoxemia mice survival. Chin J Pathol 2003; 19: 799-802.
8. Saiki I, Matsumoto Y, Murata J, Makabe T, Yoneda J, Okuyama H, et al. Recombinant fusion polypeptide with cell- and heparin-binding domains of fibronectin inhibits liver metastasis of L5178Y-ML25 lymphoma cells. Jpn J Cancer Res 1991; 82: 1120-9.
9. Fan Q, Feng ZH, Zhang GM, Zhang H, Cao HQ. Effect of recombinant human fibronectin polypeptide CH50 on growth and metastasis of melanoma. Acta Pharmacol Sin 1999; 20: 175-8.
10. Ausuble FM, Brent R, Kingston RE, Moore DD, Seidman JJ, Smith JA, et al. Short protocols in molecular biology. 2nd ed. Beijing: Science Publishers; 1998. p 72-107.
11. Kimizuka F, Ohdate Y, Kawase Y, Shimojo J, Taguchi Y, Hashino K, et al. Role of type III homology repeats in cell adhesive function within the cell-binding domain of fibronectin. J Biol Chem 1991; 266: 3045-51.
12. Leist M, Gantner F, Bohlinger I, Tiegs G, Germann PG, Wendel A. Tumor necrosis factor-induced hepatocyte apoptosis precedes liver failure in experimental murine shock models. Am J Pathol 1995; 146: 1220-34.
13. Lotem J, Cragoe EJ Jr, Sachs L. Rescue from programmed cell death in leukemic and normal myeloid cells. Blood 1991; 78: 953-60.
14. Cronan JE Jr. Biotination of proteins in vivo. A post-translational modification to label, purify, and study proteins. J Biol Chem 1990; 265: 10327-33.
15. Thompson C, Blumenstock FA, Saba TM, Feustel PJ, Kaplan JE, Fortune JB, et al. Plasma fibronectin synthesis in normal and injured human as determined by stable isotope incorporation. J Clin Invest 1989; 84: 1226-35.
16. Hishinuma I, Nagakawa J, Hirota K, Miyamoto K, Tsukidate K, Yamanaka T, et al. Involvement of tumor necrosis factor-alpha in development of hepatic injury in galactosamine-sensitized mice. Hepatology 1990; 12: 1187-91.
17. Bohlinger I, Leist M, Gantner F, Angermuller S, Tiegs G, Wendel A. DNA fragmentation in mouse organs during endotoxin shock. Am J Pathol 1996; 149: 1381-93.
18. Kondo T, Suda T, Fukuyama H, Adachi M, Nagata S. Essential roles of the Fas ligand in the development of hepatitis. Nat Med 1997; 3: 409-13.
19. Zhou BR, Gumenscheimer M, Freudenberg M, Galanos C. A striking correlation between lethal activity and apoptotic DNA fragmentation of liver in response of D-galactosamine-sensitized mice to a non-lethal amount of lipopolysaccharide. Acta Pharmacol Sin 2003; 24: 193-8.