Water and electrolyte absorption from hypotonic oral rehydration solution in rat small intestine and colon

Pediatrics International

Volumn 46, Issue 3, 2004, Pages 315-321

  Nishinaka, Daisuke ^a,b   Kishino, Fumiharu ^a   Matsuura, Akihiro ^a  

^a Shimizu Pharmaceutical Co Ltd   (Japan)

^b AJINOMOTO CO INC   (Japan)

Author keywords

Colon; Oral rehydration solutions; Osmolality; Small intestine; Sodium absorption

Indexed keywords

ELECTROLYTE; ORAL REHYDRATION SOLUTION; SODIUM; WATER;

ANESTHESIA; ANIMAL EXPERIMENT; ARTICLE; COLON; COLON ABSORPTION; CONTROLLED STUDY; INTESTINE ABSORPTION; MALE; NONHUMAN; OSMOLALITY; PERFUSION; PRIORITY JOURNAL; RAT; SMALL INTESTINE; SODIUM EXCRETION; WATER ABSORPTION;

ANIMALS; CHLORIDES; COLON; FLUID THERAPY; HYPOTONIC SOLUTIONS; INTESTINAL ABSORPTION; INTESTINE, SMALL; ISOTONIC SOLUTIONS; MALE; OSMOLAR CONCENTRATION; RATS; RATS, WISTAR; SODIUM; WATER-ELECTROLYTE BALANCE;

EID: 2942536760     PISSN: 13288067     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1442-200x.2004.01887.x     Document Type: Article

References (26)

1. Mahalanabis D, Choudhuri AB, Bagchi NG, Bhattacharya AK, Simpson TW. Oral fluid therapy of cholera among Bangladesh refugees. Bull. WHO 2001; 79: 473-9.
2. Zhou Y, Li L, Kim B et al. Rotavirus infection in children in Japan. Pediatr. Int. 2000; 42: 428-39.
3. Guarino A, Albano F, Guandalini S. Working Group on Acute Gastroenteritis. Oral rehydration: toward a real solution. J. Pediatr. Gastroenterol. Nutr. 2001; 33: S2-12.
4. Fuchs GJ. A better oral rehydration solution? BMJ 2001; 323: 59-60.
5. Farthing MJG. Oral rehydration: an evolving solution. J. Pediatr. Gastroenterol. Nutr. 2002; 34: S64-7.
6. Sandhu BK, Christobal FL, Brueton MJ. Optimising oral rehydration solution composition in model systems: studies in normal mammalian small intestine. Acta. Paediatr. Scand. Suppl. 1989; 364: 17-22.
7. Farthing MJG. Studies of oral rehydration solutions in animal models. Clin. Therap. 1990; 12: 51-62.
8. Cunha Ferreira RMC, Elliott EJ, Watson AJM, Brennan E, Walker-Smith JA, Farthing MJG. Dominant role for osmolality in the efficacy of glucose and glycine-containing oral rehydration solutions: studies in a rat model of secretory diarrhoea. Acta. Paediatr. 1992; 81: 46-50.
9. Lifshitz F, Wapnir RA. Oral hydration solutions: experimental optimization of water and sodium absorption. J. Pediatr. 1985; 106: 383-9.
10. Hunt JB, Carnaby S, Farthing MJG. Assessment of water and solute absorption from experimental hypotonic and established oral rehydration solutions in secreting rat intestine. Aliment. Pharmacol. Therap. 1991; 5: 273-81.
11. Hunt JB, Thillainayagam AV, Salim AFM, Canaby S, Elliott EJ, Farthing MJG. Water and solute absorption from a new hypotonic oral rehydration solution: evaluation in human and animal perfusion models. Gut 1992; 33: 1652-9.
12. Pillai GV, Brueton MJ, Burston D, Sandhu BK. Evaluation of effects of varying solute content on the efficacy of oral rehydration solutions in a rat model of secretory diarrhoea. J. Pediatr. Gastroenterol. Nutr. 1994; 18: 457-60.
13. Elliott EJ, Watson AJM, Walker-Smith JA, Farthing MJG. Search for the ideal oral rehydration solution: studies in a model of secretory diarrhoea. Gut 1991; 32: 1314-20.
14. Thillainayagam AV, Carnaby S, Dias JA, Clark ML, Farthing MJG. Evidence of a dominant role for low osmolality in the efficacy of cereal based oral rehydration solutions: studies in a model of secretory diarrhoea. Gut 1993; 34: 920-5.
15. Schedl HP. Use of polyethylene glycol and phenol red as unabsorped indicators for intestinal absorption studies in man. Gut 1966; 7: 159-63.
16. Go JT, Harper RG, Sia CG, Teichberg S, Wapnir RA. Oral rehydration solutions: increased water and sodium absorption by addition of a viscosity-enhancing agent in a rat model of chronic osmotic diarrhea. J. Pediatr. Gastroenterol. Nutr. 1994; 19: 410-6.
17. Hunt JB, Elliott EJ, Farthing MJG. Comparison of rat and human intestinal perfusion models for assessing efficacy of oral rehydration solutions. Aliment. Pharmacol. Therap. 1991; 5: 49-59.
18. Spring KR. Routes and mechanism of fluid transport by epithelia. Annu. Rev. Physiol. 1998; 60: 105-19.
19. Curran PF. Na, Cl and water transport by rat ileum in vitro. J. General Physiol. 1960; 43: 1137-48.
20. +-glucose cotransporter is a molecular water pump. J. Physiol. 1998; 508: 15-21.
21. Koyama Y, Yamamoto T, Tani T et al. Expression and localization of aquaporins in rat gastrointestinal tract. Am. J. Physiol. 1999; 276: C621-7.
22. Wang KS, Ma T, Filiz F et al. Colon water transport in transgenic mice lacking aquaporin-4 water channels. Am. J. Physiol. Gastrointest. Liver. Physiol. 2000; 279: G463-70.
23. Duc C, Farman N, Canessa CM, Bonvalet JP, Rossier BC. Cell-specific expression of epithelial sodium channel α, β, and γ subunits in aldosterone-responsive epithelia from the rat. localization by in situ hybridization and immunocytochemistry. J. Cell. Biol. 1994; 127: 1907-21.
24. Leichus LS, Goldhill JM, Long LD et al. Effects of rotavirus on epithelial transport in rabbit small intestine. Dig. Dis. Sci. 1994; 39: 2202-8.
25. +-solute cotransport activities in young rabbits. Am. J. Physiol. Gastrointest. Liver Physiol. 2000; 279: G587-96.
26. Field M. Intestinal ion transport and the pathophysiology of diarrhea. J. Clin. Invest. 2003; 111: 931-43.