Pharmacological characterization of canine bradykinin receptors in prostatic culture and in isolated prostate

British Journal of Pharmacology

Volumn 142, Issue 2, 2004, Pages 297-304

  Srinivasan, Dinesh ^a   Burbach, Leah R ^a   Daniels, Donald V ^a   Ford, Anthony P D W ^a   Bhattacharya, Anindya ^a  

^a ROCHE BIOSCIENCE   (United States)

Author keywords

Benign prostate hyperplasia; Bradykinin; Bradykinin receptor 2; Dog; Fluorometric imaging plate reader; Immunohistochemistry; Isolated prostate; Prostate epithelial cells; Prostate stromal cells

Indexed keywords

ACTIN; ANTIBODY; BRADYKININ B1 RECEPTOR AGONIST; BRADYKININ B1 RECEPTOR ANTAGONIST; BRADYKININ B2 RECEPTOR AGONIST; BRADYKININ B2 RECEPTOR ANTAGONIST; BRADYKININ RECEPTOR; BRADYKININ[1-8]; CALCIUM ION; CYTOKERATIN; ICATIBANT; VIMENTIN;

ANIMAL CELL; ANIMAL TISSUE; ANTIBODY SPECIFICITY; ARTICLE; CALCIUM CELL LEVEL; CALCIUM MOBILIZATION; CELL CULTURE; CELL SPECIFICITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOG; EPITHELIUM CELL; FLUOROMETRY; IMAGING SYSTEM; ISOLATED ORGAN; MALE; MUSCLE ISOMETRIC CONTRACTION; NONHUMAN; ORGAN CULTURE; PRIORITY JOURNAL; PROSTATE; PROTEIN ANALYSIS; PROTEIN FUNCTION; STATISTICAL SIGNIFICANCE;

AMINO ACID SEQUENCE; ANIMALS; BRADYKININ; CALCIUM; CELLS, CULTURED; CHO CELLS; CRICETINAE; DOGS; DOSE-RESPONSE RELATIONSHIP, DRUG; MALE; ORGAN CULTURE TECHNIQUES; PROSTATE; RECEPTOR, BRADYKININ B2;

EID: 2942515947     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0705757     Document Type: Article

References (30)

1. ALTAMURA, M., MEINI, S., QUARTARA, L. & MAGGI, C.A. (1999). Nonpeptide antagonists for kinin receptors. Regul. Peptides, 80, 13-26.
2. ANDRAWISS, M., OPOLON, P., BENIHOUD, K., DEVAUCHELLE, P., DI FALCO, N., VILLETTE, J-M., KREMER, E., SAULNIER, P., BERTHON, P., PERRICAUDET, M. & CUSSENOT, O. (1999). Adenovirus-mediated gene transfer in dog prostate: a preclinical study of a relevant model system for gene therapy of human prostatic cancer. Prostate Cancer Prostatic Dis., 2, 25-35.
3. BARKI-HARRINGTON, L. & DAAKA, Y. (2001). Bradykinin induced mitogenesis of androgen independent prostate cancer cells. J. Urol., 165, 2121-2125.
4. BLAUKAT, A. (2003). Structure and signaling pathways of kinin receptors. Andrologia, 35, 17-23.
5. CAMPBELL, D.J. (2001). The kallikrein-kinin system in humans. Clin. Exp. Pharmacol. Physiol., 28, 1060-1065.
6. CHARLESWORTH, C.M., YOUNG, C.Y., MILLER, V.A. & TINDALL, D.J. (1999). Kininogenase activity of prostate-derived human glandular kallikrein (hK2) purified from seminal fluid. J. Androl., 20, 220-229.
7. 50) of an enzymatic reaction. Biochem. Pharmacol., 22, 3099-3108.
8. FICHTNER, J., GRAVES, H.C., THATCHER, K., YEMOTO, C. & SHORTLIFFE, L.M. (1996). Prostate specific antigen releases a kinin-like substance on proteolysis of seminal vesicle fluid that stimulates smooth muscle contraction. J. Urol., 155, 738-742.
9. HECQUET, C., TAN, F., MARCIC, B.M. & ERDOS, E.G. (2000). Human bradykinin B(2) receptor is activated by kallikrein and other serine proteases. Mol. Pharmacol., 58, 828-836.
10. HESS, J.F., BORKOWSKI, J.A., YOUNG, G.S., STRADER, C.D. & RANSOM, R.W. (1992). Cloning and pharmacological characterization of a human bradykinin (BK-2) receptor. Biochem. Biophys. Res. Commun., 184, 260-268.
11. HESS, J.F., HEY, P.J., CHEN, T-B., O'BRIEN, J., OMALLEY, S.S., PETTIBONE, D.J. & CHANG, R.S.L. (2001). Molecular cloning and pharmacological characterization of the canine B1 and B2 bradykinin receptors. Biol. Chem., 382, 123-129.
12. HOULE, S., MOLINARO, G., ADAM, A. & MARCEAU, F. (2003). Tissue kallikrein actions at the rabbit natural or recombinant kinin B2 receptors. Hypertension, 41, 611-617.
13. HOWL, J. & PAYNE, S.J. (2003). Bradykinin receptors as a therapeutic target. Expert Opin. Ther. Targets, 7, 277-285.
14. HUANG, S.C.M., HSIAO, L., CHIEN, C., WANG, C., CHIU, C., TSAI, R.J.F. & YANG, C. (2002). Characterization of bradykinin receptors in canine cultured corneal epithelial cells: pharmacological and functional studies. J. Biomed. Sci., 9, 213-222.
15. JARNAGIN, K., BHAKTA, S., ZUPPAN, P., YEE, C., HO, T., PHAN, T., TAHILRAMANI, R., PEASE, J.H.B., MILLER, A. & FREEDMAN, R. (1996). Mutations in the B2 bradykinin receptor reveal a different pattern of contacts for peptide agonists and peptide antagonists. J. Biol. Chem., 271, 28277-28286.
16. KOOISTRA, A., ELISSEN, N.M., KONIG, J.J., VERMEY, M., VAN DER KWAST, T.H., ROMIJN, J.C. & SCHRODER, F.H. (1995). Immunocytochemical characterization of explant cultures of human prostatic stromal cells. Prostate, 27, 42-49.
17. 2+ mobilization in canine cultured tracheal epithelial cells. Br. J. Pharmacol., 126, 1341-1350.
18. MEINI, S., PATACCHINI, R., GIULIANI, S., LAZZERI, M., TURINI, D., MAGGI, C.A. & LECCI, A. (2000). Characterization of bradykinin B(2) receptor antagonists in human and rat urinary bladder. Eur. J. Pharmacol., 388, 177-182.
19. MONSEES, T.K., BLOCHER, S., LODDO, C., STEGER, K. & SCHILL, W.B. (2003). Tissue kallikrein and bradykinin B2 receptors in the reproductive tract of the male rat. Andrologia, 35, 24-31.
20. NORMANDIN, D.E. & LODGE, N.J. (1996). Pharmacological characterization of the isolated canine prostate. J. Urol., 155, 1758-1761.
21. PEEHL, D.M. & SELLERS, R.G. (2000). Cultured stromal cells: an in vitro model of prostate mesenchymal biology. Prostate, 45, 115-123.
22. SCHILL, W.B. & MISKA, W. (1992). Possible effects of the kallikrein-kinin system on male reproductive functions. Andrologia, 24, 69-75.
23. SCORILAS, A., PLEBANI, M., MAZZA, S., BASSO, D., SOOSAIPILLAI, A.R., KATSAROS, N., PAGANO, F. & DIAMANDIS, E.P. (2003). Serum human glandular kallikrein (hK2) and insulin-like growth factor 1 (IGF-1) improve the discrimination between prostate cancer and benign prostatic hyperplasia in combination with total and %free PSA. Prostate, 54, 220-229.
24. SIMPSON, P.B., WOOLLACOTT, A.J., HILL, R.G. & SEABROOK, G.R. (2000). Functional characterization of bradykinin analogues on recombinant human bradykinin B1 and B2 receptors. Eur. J. Pharmacol., 392, 1-9.
25. STEIDLE, C.P., COHEN, M.L. & NEUBAUER, B.L. (1990). Bradykinin-induced contractions of canine prostate and bladder: effect of angiotensin-converting enzyme inhibition. J. Urol., 144, 390-392.
26. 2+] using the fluorometric imaging plate reader (FLIPR). Methods Mol. Biol., 114, 125-133.
27. WALDEN, P.D., LEFKOWITZ, G.K., ITTMANN, M., LEPOR, H. & MONACO, M.E. (1999). Mitogenic activation of human prostate-derived fibromuscular stromal cells by bradykinin. Br. J. Pharmacol., 127, 220-226.
28. WATERS, D.J., SAKR, W.A., HAYDEN, D.W., LANG, C.M., MCKINNEY, L., MURPHY, G.P., RADINSKY, R., RAMONER, R., RICHARDSON, R.C. & TINDALL, D.J. (1998). Workgroup 4: spontaneous prostate carcinoma in dogs and nonhuman primates. Prostate, 36, 64-67.
29. WATTS, S.W. & COHEN, M.L. (1991). Effect of bombesin, bradykinin, substance P and CGRP in prostate, bladder body and neck. Peptides, 12, 1057-1062.
30. WOOD, M.R., KIM, J.J., HAN, W., DORSEY, B.D., HOMNICK, C.F., DIPARDO, T.M., MURPHY, K.L., LIS, E.V., RANSOM, R.W., STUMP, G.L., LYNCH, J.J., O'MALLEY, S.S., MILLER, P.J., CHEN, T.-B., HARRELL, C.M., CHANG, R.S.L., SANDHU, P., ELLIS, J.D., BONDISKEY, P.J. & BOCK, M.G. (2003). Benzodiazepines as potent and selective bradykinin B1 antagonists. J. Med. Chem., 46, 1803-1806.